Open Science is better science. Research benefits from sharing data and scientific knowledge which is publicly available, making open science essential. The Open and Reproducible Research Group (ORRG) uses evidence-based and computational approaches to make research cultures more open, transparent and participatory through new practices and technologies. In our interdisciplinary team we combine competences in philosophy, sociology, and information science with computer science and life science. We research services, policies, and tools to investigate and foster the uptake and evaluation of Open Science practices.