The recent trend in developing safety-critical cyber-physical systems (CPS) is to move from local standalone solutions to solutions based on a distributed architecture where, e.g., safety and mission-critical operations are distributed in the device-edge-cloud continuum. A critical factor in such systems is the communication between the different components. Wireless communication provides a high level of flexibility, however, its dependability (i.e., reliability, timeliness, and availability) is heavily depending on different environmental conditions: for example, interference and multipath effects can negatively impact the communication reliability. To guarantee proper and safe operation for such wirelessly connected safety-critical CPS, meeting given end-to-end (E2E) dependability requirements is highly important. Therefore, we want to evaluate different solutions that try to tackle the problem of ensuring E2E dependability in deviceedge- cloud based architectures.