IBioSys Team Building took place in September.

We had a lot of fun climbing the Schockl and spending time together at the inn.

Congratulations! |We proudly congratulate Wilhelm Festl and Alexander Luttenberger for the accomplished defense of their excellent master's thesis:

• Synthesis of Alkyne-Functionalized D-manno-C-Glycosides
• Development of Glycomimetics as Potential Galactosidase Inhibitors

Visit at University of Maribor

We are very grateful to Prof. Željko Knez, MSc Gal Slaček, and their team for the opportunity to visit their facilities at the University of Maribor and conduct experiments involving CO₂. 

We are happy to announce that our iMOOXs Introduction into Green Process Engineering is online.

The MOOXs is part of the English taught Master program Green Process Engineering and is thought as an introductory lesson.

The MOOC covers four thematic areas: definitions and terminology, subsystems of the bioeconomy, transformation pathways and technologies, and practical examples from industrial practice. For each of the four thematic areas, between four and six videos are available, explaining the respective topic in more detail and providing additional information. The aim of the course is to provide an overview of the terms used in connection with "green process engineering," bioeconomy, the circular economy, and industrial ecosystems. The subsystems of the bioeconomy, such as the wood-based, water-based, and plant-based bioeconomy, are described. The transformation pathways defined by the European Commission and the relevant measures for achieving zero emissions by 2050 are then summarized, before some relevant examples from industry are presented.

Prof. Karin Stana-Kleinschek and Prof. Marlene Kienberger

Please find also enclosed the link to our MOOXS

https://imoox.at/course/InGPE

Seaweed meets Papaya!

Happy to share that our recent publication in BioconjugateChemistry was featured on the cover! https://pubs.acs.org/toc/bcches/36/9 Looking forward to extending the concept to other peptides and polysaccharides — and to exploring new ways to control the enzyme during cross-linking. Thanks to all co-authors from IBIOSYS and PTC at TUGraz and LCPP at UM

[Philipp Loibner, David Bučak-Gasser, Katharina Schober, Tobias Steindorfer, Monika Brandtner,Tobias Dorn, Tanja Wrodnigg, Dmytro Neshchadin, Georg Gescheidt-Demner, Matej Bračič, Florian Lackner, Tamilselvan Mohan, Rupert Kargl, Karin Stana Kleinschek]

As part of the PMWS Workshop https://www.tugraz.at/projekte/pmws/home we were pleased to host Dr. Marjan Bele from the National Institute of Chemistry.

The 9th EPNOE International Polysaccharide Conference was from August 25th to 28th, 2025

IBioSys was represented by:

• Enzyme-Driven Crosslinking of 3D-Printed Biosaccharide Hydrogels for Enhanced Tissue Engineering Scaffolds - Tamilselvan Mohan
• Covalent crosslinking of alginate by native chemical ligation - David Bučak Gasser
• Chemo-enzymatic synthesis of peptide Bridged glycan networks - Rupert Kargl
• Surface Modification of Polycaprolactone 3D Scaffolds Using Hyaluronic Acid-Glycine Peptide Conjugates to Enhance Endothelial Cell Adhesion - Karin Stana Kleinschek
• Epnoe Research Roadmap 2040 Innovation Potential - Karin Stana Kleinschek

 IBiosys say Goodbye to Prof Jennifer Rose Weiser Cooper Union Ney York City- USA and MSc Gal Slacek, University of Maribor- Slovenia

We are delighted to have been your host.

 22nd European Carbohydrate Symposium 6th - 10th July 2025, Gdansk Polen

 Congratulation | Outstanding Master Thesis Award

IBioSys proudly congratulates Lisa Schmedler on her Master's Thesis '3D Printing of Biocatalysts and Applications in Continous Flow', which was awarded with the 'Outstanding Master Thesis Award' at the Science Day 2025 of the Faculty 'Technical Chemistry, Chemical and Process Engineering and Biotechnology of Graz University of Technology.

Congratulations! | We are delighted and congratulate Herwig Prasch on the successful defence of his doctoral thesis Glycomimetics-Based Small Molecules as Tools for Ligand Directed Chemistry of Glycoside Hydrolases.

Congratulations! |We proudly congratulate Elena Spari and Daniel Pint  for the accomplished defense of their excellent master's thesis:

• Synthesis and biological evaluation of small molecule glycomimetic-based ligand directed chemistry probes: Improving labeling efficiency and selectivity of glycoside hydrolases
• Scale-Up of 3D-Printed Bioreactors for Continuous-Flow Biotransformations

Prof. Jennifer Weiser from New York reports on her stay at IBioSys in Graz

 Gedruckte Haut soll Tierversuche ersetzen 

TU Graz news Forschung

Ein Forschungsteam der TU Graz und des indischen Vellore Institute of Technology entwickelt ein mit lebenden Zellen ausgestattetes, 3D-gedrucktes Hautimitat, um Nanopartikel aus Kosmetika ohne Tierversuche testen zu können.

The 2025 AMS Poster day was on 04.02.2025

Our Institute was represented by:

• Biopolymeric Alginate Composites - Sustainable Approach for Advanced Material Applications- Cornelia Ott, Institute of Architecture and Media
• Scale-Up of 3D-Printed Bioreactors for Continuous-Flow Biotransformation- Daniel Pint, IPPT/IBioSys
• Master’s Thesis: Covalent Crosslinking of Alginate by Native Chemical Ligation (NCL)- David Bucak Gasser, IBioSys
• 3D-Printed Alginate-NFC Scaffolds functionalized with HP-beta-CD/CBD Complexes. A Novel Approach for Enhanced Solubility and Drug Delivery of CBD- Dennis A. Silva-Cullishpuma, Universidad Catolica San Antonio de Murcia
• Development of 3D-Printed Polysaccharide Biomaterials using a Dual-Enzyme Crosslinking System: Structural Stabilization, Mechanical Integrity and Swelling Behavior- Miriam Zeller, IBioSys
• Investigating the fibrillation process and the characteristics of nanocellulose obtained through high-pressure homogenization- Simon Brunner, IBioSys
• Chemical Modification of Chitosan: A Versatile Strategy for Developing Bioactive Thin Films and Bulk Materials- Tobias Dorn, IBioSys
• Flavin-based crown ethers with ion-sensing properties- Vojtech Krusbersky, Brno University of Technology; IBioSys

We at  IBioSys welcome Prof. Yottha Srithep from Mahasarakham University -Thailand.

He is going to work on "Development of solvent-free of polylactide stereocomplex blended with nanofibrillated cellulose (NFC) for tissue engineering scafolds" project with us.

Prof. Srithep will stay with us from March to August 2025.

At IBioSys we are very pleased about Prof. Jennifer Weiser staying at our Institute.  

Prof Weiser receives Fulbright U.S. Scholar Award for 2024-25. As a Fullbright Scholar, Dr. Weiser has joined the faculty of Graz University of Technology as a Visiting Professor at the Institute of Chemistry and Techology of Biobased Systems (IBioSys, Prof. Dr. Karin Stana-Kleinschek). Her experiance in innovative engineering education methods as well as in the newest research tools for the development of Drug Formulation, Delivery and Biomaterials will be ennoble our academic enviroment.

Prof. Weiser will stay with us from Febuary to July 2025.

More information

28th Austrian Carbohydrate Workshop 13.-14.2.2025 @BOKU, Vienna

IBioSys and Glycogroup proudly presented latest results in two oral presentations and  three posters! It was a scientifically inspiring and social happy event as every year!

Congratulations! |We proudly congratulate Philipp Loibner, Miriam Zeller and David Bucak Gasser for the accomplished defense of their excellent master's thesis:

• Covalent Crosslinking of Alginate using Amino Acid-derived Small-molecular Agents
• Development of 3D-Printed Scaffolds via Dual Enzyme Crosslinking of Chemically Modified Alginate and Nanofibrous Cellulose Based Hydrogels
• Covalent Crosslinking of Alginate by Native Chemical Ligation (NCL) – An Innovative Approach Towards Novel Hydrogels for Biomedicine

 Special Issue in Chemical Monthly 

We are pleased to share with you the special issue in Monatshefte für Chemie - Chemical Monthly: "Carbohydartes - A sweet Austrian Screenshot"

Issue Editors: Tanja M. Wrodnigg, Christian Stanetty, Markus Blaukopf

More Infomation

 Merry Christmas and a Happy and Healthy 2025!

 Chemietage 2024 article in Chemiereport.at

Have a look at the article in chemiereport 2024.7 about the Chemietage 2024.

Click here for the whole chemiereport

©Chemiereport 2024.07

 European patent EP4215340A1

We are excited to share the european patent of Florian Lackner, Karin Stana Kleinschek and Rupert Kargl:

Device for forming structures from a nanoconductive matrix material comprising fibers and method of aligning fibers in a nonconductive matrix material (EP4215340A1)

More Info

 India-Austria Bilateral Project

After our colleagues Tamilselvan Mohan and Florian Lackner visited our cooperation partners at the Vellore Institute of Technology (India).

We now had the pleasure of welcoming Prof. Amit Kumar Jaiswal to our institute, who gave a lecture on the research activities of his group. 

 20^th GÖCH Chemietage 2024 - Biobased Chemistry and Technology 

Chemietage 2024 have been held from 23^rd to 25^th  of September at TUGraz.

There were many fascianting oral and poster presentations, and it was a true honor to have Ben Feringa as keynote speaker. 

A big thank to everyone who helped to make this conference possible!

 31^st International Carbohydrate Symposium

IBioSys was well represented at the 31^st International Carbohydrate Symposium ICS 2024 in Shanghai, Juli 14-19 2024, with an invited talk and 4 posters on the hottest scientific newes from our lab. It has been an inspiring conference in the astonishing city Shanghai.

 Congress Award Graz

We are pleased to inform you that we have been awarded the Congress Award of the City of Graz for the organisation of the 8th International Polysaccharide Conference of the EPNOE.

Thanks to everyone who helped us and made the conference possible!

More Information

Pictures: © MCG/Wiesner

 Congratulation | Outstanding Master Thesis Award

IBioSys proudly congratulates André Culum on his Master's Thesis Synthesis of glycomimetics as probes for activity based protein profiling, which was awarded for the first time with the   'Outstanding Master Thesis Award' of the Faculty 'Technical Chemistry, Chemical and Process Engineering and Biotechnology of Graz University of Technology.

Congratulations! | We proudly congratulate Esther Ledl, Katharina Schober, and Michael Lamprecht for the accomplished defense of their excellent master's thesis:

• Development of a renewable, hydrophobic coating for textile fibers by Esther Ledl,
• Enzymatic Cross-Linking of Polysaccharide-Amino Acid Conjugates by Katharina Schober, and
• Investigation of in-situ aligment of dielectric fibers with an electic field in extrusion-based 3D printing by Michael Lamprecht.

Congratulations! | We are delighted and congratulate Florian Lackner on the successful defence of his doctoral thesis 3D Printing of Polysaccharides for Tailored Microstructures in Biomaterials

Campusausstellung: Frauen der TUGraz im Fokus

Vom 27. Mai bis 13. Juni 2024 zeigt die Ausstellung zum Gestaltungswettbewerb "Erinnerungen bauen: Pionierinnen der TU Graz" zehn architektonische Installationen, die Studierendenteams am Institut für Grundlagen der Konstruktion und des Entwerfens (KOEN) erarbeitet haben, um Pionierinnen der TU Graz räumlich zu vergegenwärtigen. Zu sehen sind die Arbeiten am Campus Neue Technik in der Kopernikusgasse 24 (Foyer bei Hörsaal H). Veranstalter*innen sind gemeinsam mit KOEN der Alumni-Verein alumniTUGraz 1887 und dessen WomenUniverse-Netzwerk.

Congratulation! Professor Jennifer Weiser Receives Fullbright U.S. Scholar Award for 2024-25| As a Fullbright Scholar, Dr. Weiser will join the faculty of Graz University of Technology as a Visiting Professor at the Institute of Chemistry and Techology of Biobased Systems (IBioSys, Prof. Dr. Karin Stana-Kleinschek). 

At IBioSys we are very pleased about Prof. Weiser staying at our Institute. Her experiance in innovative engineering education methods as well as in the newest research tools for the development of Drug Formulation, Delivery and Biomaterials will be ennoble our academic enviroment.

Prof. Weiser will stay with us from Febuary to July 2025.

More information

Congratulations! | We congratulate Rupert Kargl on his habilitaion (venia docendi) in the field of material sience of bioorganic substances!

 Announcement: First decive in our new IBioSys laboratories| We are pleased to announce that we finally installed the GEA Panther Homogenizer as the first device in our new IBioSys laboratories.

We are looking forward to the production of nanofibrillated cellulose (NFC) and to new collaborations

 Kraftfasern auf der Überholspur | A contribution about the Cellulose and Polysaccharide research in Austria, is just published in the GEO magazine.

Read the article (DE)

Open Professorship position for Biopolymers | at Friedrich Schiller University Jena, Germany 

More information 

Open Postdoc position | at Sao Carlos Chemistry Institute (University of Sao Paulo) 

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What is the potential of polysaccharides in biomaterial science? | Biopolymers and carbohydrates have a significant potential to be used as biomaterials due to their very large structural variability and biological origin to which living cells respond. Read more

EPNOE Research Roadmap 2040 Launch Event | A joint effort of more than 20 high-level scientists who aim to address the most relevant scientific questions around sustainable solutions based on biomass and polysaccharides. This launch event offers a platform for discussion, encouraging exchanges among different stakeholders with common goals. The Research Roadmap Chairs and Vice Chairs will present their chapters, covering five strategic areas: Materials & Engineering, Food & Nutrition, Biomedical Applications, Basic Sciences - Chemistry, Biology & Physics, and Skills.

• More details
• Save your spot now

What an experience at the #WebSummit 2022 in Lisbon!! | Our colleagues Florian Lackner and Rupert Johann Kargl presented our technology on 3D printed biomimetic aorta models at the AUSTRIA NIGHT – reveals BOLD.

We are grateful for this opportunity and invitation from the Austrian Federal Economic Chamber (WKO).

A big thank you to our collaboration partners from Ludwig-Maximilians-Universität München, Prof. Dr. Nikolaos Tsilimparis, Jan Stana, MD, PhD, and Maximilian Grab, MSc, for contributing state-of-the-art vascular 3D models and EVAR implants.

We had a blast with our teammates at the 5^th EPNOE Junior Scientist Meeting (Aveiro, Portugal)! | Were you there? We contributed:

• Session 3: Biorefinery and biomass-derived polysaccharides was organised by our team member Rupert Kargl & Andreea Scutaru as chairs.
• Award-winning talk: 3D printing and alignment of NFC-Alginate nanocomposites with highly tunable properties by Florian Lackner
• Poster: Synthesis of C-glycosidic entities for the modification of polysaccharide matrixes by Tobias Dorn
• Poster: In-situ alignment of dielectric fibers with electric fields in extrusion processes by Florian Lackner

Congratulations! | Our PhD student Florian Lackner was recognised for the Best Oral Communication Award at the 5^th EPNOE Junior Scientist Meeting in Aveiro, Portugal for his talk on 3D printing and alignment of NFC-alginate nanocomposites with highly tunable properties.

Open Postdoc position | Chemical Glycobiology at the CIC bioGUNE (Bilbao, Spain)

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the 25th Austrian Carbohydrate Workshop | was a success! A big THANK YOU to all our participants of the event, which took place from July 7^th-8^th, 2022, at TU Graz.

The overall enthusiasm and positive spirit made our time together both productive and fun.

THANK YOU

• To all for coming!
• To all the speakers and poster presenters!
• To all the IBioSys staff for all their work and help!
• To all the sponsors! None of this would have been possible without your support.

Gallery      Website

Congratulations! | We proudly congratulate Melanie Zündel, Stefan Schwaiger, und Maximilian Novak for the accomplished defense of their excellent master's thesis:

• Synthesis of Iminosugar-Based Glycomimetics for Glycosidase Profiling by Melanie Zündel,
• Synthesis of Alkyne Functionalized Carbohydrate Building Blocks in the D-manno Configuration for the Modification of Cellulose by Stefan Schwaiger, and
• 3D Printing, Stabilization, and Characterization of Nanofibrillated Cellulose-Alginate Scaffolds by Maximilian Novak.

Learning from nature and promoting young people | In the "Woche" interview, our professor Karin Stana Kleinschek talks about research, internationality, and what she would like to pass on to young scientists.

Read the interview on page 12 (DE)

Congratulations! | Our Master's student Ivan Knechtl was awarded the WKO Steiermark research grant for business-related Bachelor's and Master's Theses. A total of 20 scholarships were awarded this year after more than 100 submissions for the scholarship program (awards were made by a 10-person expert jury).

Ivan's Master's Thesis: 3D printed medical models used in aortic surgeries

See the video

Our colleague Rupert Johann Kargl on the exciting field we are working in @ Nanotexnology International Conferences & Exhibition on Nanotechnologies, Organic Electronics & Nanomedicine.

See the video

  Austrian Carbohydrate Network | the 25^th Austrian Carbohydrate Workshop (ACW) 2022 at TU Graz

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Grants Available! | Open Short Term Scientific Missions (STSM) grant.

• Documents & Guidelines

  Update: Austrian Carbohydrate Network | the 25^th Austrian Carbohydrate Workshop (ACW) 2022 at TU Graz

Open for registration - deadline June 20^th, 2022  More info

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New entrance hall to IBioSys | A new picture graces our entrance hall created by Ilse Leitgeb-Feichtenberger, "IBioSysLabs".

ADVANCED MATERIALS SCIENCE Poster Day 2022 | In the coming Poster Day of the interdisciplinary network at the TU Graz, prof. Karin Stana Kleinschek will give a lecture on Biopolymers in Biomedical Applications, and Florian Lackner a poster presentation on In-situ alignment of dielectric fibers with electric fields in extrusion processes. more info

Interational ZELLCHEMING Conference Invited Lecture | As part of the excellent scientific program, prof. Karin Stana Kleinschek from the IBioSys will give an invited lecture on Biopolymers and their potential application in medicine. The conference gathers researchers from science and industry who are interested into R&D in polysaccharides, paper-based materials, and bioeconomy. more info

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Technology Offer | In situ alignment of dielectric fibers using electric fields in extrusion processes

• Development status: Proof of concept
• Cooperation options: Licensing, Sale, Technical cooperation

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Our recent publication was highlighted as the supplementary cover on ACS Biomacromolecules (March 14, 2022 - Volume 23, Issue 3)

EPNOE Webinar  |  Registration

Heinzel Mondi Sappi Award | recognizes outstanding publications by early stage researchers

• Deadline: February 28th 2022

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5 ECTS Cellulose Wet Spinning course (2 days) | short virtual winter course organized by Aalto University and Technical University of Graz.

• Enrolment deadline: March 1st, 2022
• Course code: CHEM-LV02
• Lecturer: Prof. Herbert Sixta
• Course assignment examiner: Prof. Michael Hummels

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Grants Available! | Open ITC Conference Grants and Short Term Scientific Missions (STSM) grants for Young researchers & Innovators.

• User guide
• Documents & Guidelines

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Announced Lectures in Summer Semester 2022 | IBioSys offers the following elective subjects:

• 3-D-Print info
• Transformation and Shaping of Biobased Systems info
• Macromolecular Materials and Material Technologies III - Composite Materials info

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EPNOE Webinar  |  Registration

Congratulations! | We are proud to announce that our master student Ivan Knechtl received a research grant funded by the Austrian Economic Chamber-WKO Steiermark for his research on the master thesis titled 3D printed medical models used in aortic surgeries.

The scope of this master thesis is the development of 3D printed biomimetic models of the human aorta that have very similar biomechanical and pressure resistance properties when compared to the real organ. This will be achieved by combining biocomposite material and polymer science with the latest 3D manufacturing technologies.

Congratulations! | We proudly congratulate Melina Much and Tadeja Katan for the accomplished defense of their excellent master's thesis:

• Materials for Additive Manufacturing and Molding of Biomimetic Aorta Models by Melina Much and
• Chitosan and polyvinylidene fluoride thin films for solid phase peptide synthesis by Tadeja Katan.

Upcoming webinar on chitin and polysaccharide science | Brought to you in cooperation with the European Chitin Society. Join via ZOOM

Congratulations! | We proudly congratulate Tobias Dorn MSc BSc for the accomplished defense of his excellent Master's Thesis in Chemistry.

• Thesis title: "Synthesis of C-Glycosyl Type Sugar-Amino Acid Building Blocks for "on Surface" Glycopeptides Fabrication"

Congratulations! | To our new PhD Andreas Wolfsgruber MSc BSc for the accomplished defense of his excellent Doctoral Thesis.

Dissertation title: "Synthesis of Iminosugar Based Glycomimetics for Activity Based Protein Profiling of Carbohydrate Processing Enzymes"

We need to understand nature better. An interview about IBioSys with Karin Stana Kleinschek, published in the Spirit of Styria - the new business magazine for Styria. link

IBioSys at Polymer Meeting 14 (PM14) | Graz University of Technology, Aug. 30.-Sep. 2., 2021.

• Biomimetic models of the aortic arch for surgical planning
• 3D printing and stabilization of nanofibrillated cellulose-alginate scaffolds by different crosslinking methods
• Initiated chemical vapor deposition of a carbohydrate based polymer
• Synthesis of all sugar cellulose conjugates by click chemistry
• Is 3-O-Methyl-α,β-D-glucose a substrate for alginate producing Azotobacter vinelandii?
• Solid phase synthesis of various amino acid sequences on chitosan thin films

Book of abstracts

Webinar on chitin and polysaccharide science | Brought to you in cooperation with the European Chitin Society. When? August 31th at 11 AM (CET). More info

Medical application of the chitosan in special areas of use by Marcin H. Struszczyk (Institute of Security Technologies “MORATEX”).

Join via ZOOM

Webinar on chitin and polysaccharide science | Brought to you in cooperation with the European Chitin Society. When? July 27th at 11 AM (CET). More info

Chitosan-based nanomaterials for gene/drug delivery, and antibacterial control by Francisco Goycoolea (University of Leeds).

Dually crosslinked chitosan nanoparticles block quorum sensing and target bacterial growth at specific cell densities by Celina Vila (University of Santiago de Compostela).

Join via ZOOM

Preparation of the model films in our labs using new spin coater Spin200i (SPS Europe).