At the IBioSys Institute, we indulge in both fundamental and applied research in bioorganic chemistry, materials science and engineering. By blending curiosity with creativity, we host an interdisciplinary hub for innovation, bridging molecular design and advanced processing technologies to develop bio-inspired solutions for pressing medical, industrial and environmental challenges. Based at Graz University of Technology, we work at the intersection of Advanced Materials Science and Human Biotechnology Fields of Expertise (FoE) and are proud partners in the regional academic cooperations with NAWI Graz (University Graz) and BioTechMed (Medical University of Graz). As a researcher-driven institute with a strong commitment to education we strive to immerse students in the exciting and ever-evolving field of biobased systems technologies. With a strong emphasis on -indepth theoretical knowledge and hands-on practical experience, we help our students to develop the necesseary skills and confidence to address real-world challenges directly within our research labs. Our amalgamation of active research, teaching, as well as numerous collaborations with academic and industrial partners fosters an engineeing environment for perpetual knowledge and technology transfer on a local and international level.
The research activities of IBioSys implement two main research fields with a common interest "Biobased Systems" – bioactive carbohydrate based bioconjugates.
Chemistry of Biobased Systems | Our research focuses on the development of efficient and cost-effective synthetic methods for bioactive glycoconugates, glycomimetics, and molecular analogues derived from renewable resources. These compounds serve as valuable tools for profiling glycoprocessing enzymes, conducting structure-activity relationship studies, and exploring therapeutic applications for deseases related to carbohydrate metabolism.
In parallel, we design, synthsize, modify, and characterize biobased systems such as oligo- and polysaccharides for use in a range of material technologies. These include 3D printing, coating, and serface-active technologies, as well as biomedical applications and auxiliary materials for the paper and pulp industry.
Technology of Biobased Systems | We focus on the development of complex materials and conjugates based on biomolecules derived from living organism, as well as their synthetic analogues. This includes the design, synthesis, analysis, and application of both purely organic structures and organic-inorganic hybrid systems.
A key area of research is the development of advanced biomaterials, with particular emphasis on surface-specific processes such as surface functionalization. We also work on the fabrication of 3D-structured materials using cutting-edge technologies such as 3D printing and laser lithography. This involves the formulation of bio-inks, and the creation of cross-linked and self-assembling systems, with applications in tissue engineering and drug delivery.
In addition, we investigate the use of mono-, oligo- and polymers, along with their derivatives, for a variety of technical applications. These range from packaging and paper conservation to process technology in the paper- and textile industries, as well as coatings and cosmetics.
Glycogroup has been established in 1989. Over the years, we have been interested and engaged in a variety of projects involving the synthesis and biological evaluation of glycomimetics including iminosugars, carbasugars, C-glycosyl type glycoconjugates as well as various types of diagnostic compounds and probes.
Since 2005, we have successfully fostered and managed Glycogroup as a joined venture taking advantage of the synergism of our individual scientific interests and our passion for glycoscience.
Glycogroup is dedicated to high quality research in timely areas of glycosciences. Target-oriented synthetic approaches are driven by our curiosity for the biochemical activities of our glycomimetics. Nonetheless, several projects have also contributed to organic and carbohydrate methodology and mechanistic considerations.
In 2020, Glycogroup has joined the new institute for Chemistry and Technology of Biobased Systems and a newly established chair for ‘Glycochemistry’ was implemented to intensify and foster research and teaching in this significant and fast-growing field of science.
Our international collaborations include a long list of preeminent scientists in their areas who have kindly been adding their expertise to our projects.
Contact
Institut für Chemie und Technologie Biobasierter Systeme
Stremayrgasse 9
8010 Graz
- +43 (316) 873 - 32071
- ibiosys@tugraz.at