ORGC - Publications

2021

Journal Article

Rolf Breinbauer and Rita Fürst Activity‐Based Protein Profiling (ABPP) of Oxidoreductases ChemBioChem 22, 630–638, 2021 Show publication in PURE

Rolf Breinbauer Festphasen- und Flowsynthese (Trendbericht, Organische Chemie 2020) Nachrichten aus der Chemie 69, 45-47, 2021 Show publication in PURE

Rolf Breinbauer and Christian Lembacher-Fadum Simultaneous quantification of enterotoxins tilimycin and tilivalline in biological matrices using HPLC high resolution ESMS² based on isotopically ¹⁵N-labeled internal standards Talanta 222, 2021 Show publication in PURE

Rolf Breinbauer Inhibition of ATGL in adipose tissue ameliorates isoproterenol-induced cardiac remodeling by reducing adipose tissue inflammation American Journal of Physiology / Heart and Circulatory Physiology 320, H432-H446, 2021 Show publication in PURE

Rolf Breinbauer and Thomas Schlatzer Synthesis of Hydrophilic Phosphorus Ligands and Their Application in Aqueous‐Phase Metal‐Catalyzed Reactions Advanced Synthesis & Catalysis 363, 668 – 687, 2021 Show publication in PURE

2020

Journal Article

Hansjörg Weber and Rolf Breinbauer Synthesis of a Bcl9 Alpha-Helix Mimetic for Inhibition of PPIs by a Combination of Electrooxidative Phenol Coupling and Pd-Catalyzed Cross Coupling Catalysts 10, 2020 Show publication in PURE

Rolf Breinbauer, Hansjörg Weber and Michael Frieß Stereoselective synthesis of chiral thiol-containing 1,2-aminoalcohols via SmI₂-mediated coupling Tetrahedron 76, 2020 Show publication in PURE

Rolf Breinbauer Festphasen- und Flowsynthese (Trendbericht, Organische Chemie 2019) Nachrichten aus der Chemie 68, 48-49, 2020 Show publication in PURE

Rolf Breinbauer Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL) Bioorganic and Medicinal Chemistry 28, 2020 Show publication in PURE

Hansjörg Weber, Rolf Breinbauer, Christian Lembacher-Fadum and Thomas Schlatzer Pd/BIPHEPHOS is an Efficient Catalyst for the Pd‐Catalyzed S‐Allylation of Thiols with High n‐Selectivity Advanced Synthesis & Catalysis 362, 331-336, 2020 Show publication in PURE

Other Article

Rolf Breinbauer and Thomas Schlatzer Site-Selective Bioconjugation via Palladium-Mediated Allylation of Cysteine Show publication in PURE

2019

Journal Article

Rolf Breinbauer and Thomas Schlatzer Synthesis of 2-Pyrrolidinones by Palladium-Catalyzed [3+2] Cycloaddition of Isocyanates Synlett 30, 581-585, 2019 Show publication in PURE

Rolf Breinbauer Selective Formation of 4,4′-Biphenols by Anodic Dehydrogenative Cross- and Homo-Coupling Reaction Chemistry - a European Journal 25, 2713-2716, 2019 Show publication in PURE

Rolf Breinbauer Festphasen- und Flowsynthese (Trendbericht, Organische Chemie 2018) Nachrichten aus der Chemie 67, 53-54, 2019 Show publication in PURE

Rolf Breinbauer, Wolfgang Kroutil and Christian Lembacher-Fadum Klebsiella oxytoca enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities Proceedings of the National Academy of Sciences of the United States of America 116, 3774-3783, 2019 Show publication in PURE

Rolf Breinbauer Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans Journal of Lipid Research 60, 1020-1031, 2019 Show publication in PURE

Rolf Breinbauer, Christian Lembacher-Fadum and Thomas Schlatzer Labeling and Natural Post-Translational Modification of Peptides and Proteins via Chemoselective Pd-Catalyzed Prenylation of Cysteine Journal of the American Chemical Society 141, 14931-14937, 2019 Show publication in PURE

Other Article

Rolf Breinbauer Capsaicin Metabolite Synthesis by Fungal Cytochrome P450 Show publication in PURE

Rolf Breinbauer Iodonium-based Probes for the Activity-based Protein Profiling of Oxidoreductases Show publication in PURE

Rolf Breinbauer and Thomas Schlatzer Chemoselective Cysteine Bioconjugation via Palladium-Mediated Allylation Show publication in PURE

Rolf Breinbauer Iodonium-based Probes for the Activity-based Protein Profiling of Oxidoreductases Show publication in PURE

Rolf Breinbauer and Thomas Schlatzer Site-Selective Bioconjugation via Palladium-Mediated Allylation of Cysteine Show publication in PURE

Rolf Breinbauer Development of Small-molecule inhibitors of Adipose Triglyceride Lipase (ATGL) Show publication in PURE

2018

Journal Article

Rolf Breinbauer and Thomas Schlatzer Synthesis of novel ligands targeting phenazine biosynthesis proteins as a strategy for antibiotic intervention Monatshefte für Chemie - Chemical Monthly 149, 847-856, 2018 Show publication in PURE

Rolf Breinbauer Festphasen- und Flowsynthese (Trendbericht, Organische Chemie 2017) Nachrichten aus der Chemie 66, 256-257, 2018 Show publication in PURE

Rolf Breinbauer Asymmetric Reductive Carbocyclization Using Engineered Ene Reductases Angewandte Chemie / International Edition 57, 7240 –7244, 2018 Show publication in PURE

Rolf Breinbauer Asymmetrische reduktive Carbocyclisierung durch modifizierte En‐Reduktasen Angewandte Chemie 130, 7360-7364, 2018 Show publication in PURE

Rolf Breinbauer The crystal structure of monoacylglycerol lipase from M. tuberculosis reveals the basis for specific inhibition Scientific Reports 8, 2018 Show publication in PURE

Rolf Breinbauer Aliphatic hydroxylation and epoxidation of capsaicin by Cytochrome P450 CYP505X Tetrahedron 74, 6199-6204, 2018 Show publication in PURE

Rolf Breinbauer Atglistatin ameliorates functional decline in heart failure via adipocyte-specific inhibition of adipose triglyceride lipase American Journal of Physiology / Heart and Circulatory Physiology 315, H879-H884, 2018 Show publication in PURE

Rolf Breinbauer Application of Threonine Aldolases for the Asymmetric Synthesis of α-Quaternary α-Amino Acids ChemCatChem 10, 3453-3458, 2018 Show publication in PURE

Other Article

Rolf Breinbauer and Thomas Schlatzer Palladium-Mediated Allylation of Cysteine for Site-Selective Bioconjugation of Peptides and Proteins Show publication in PURE

Rolf Breinbauer, Christian Lembacher-Fadum and Thomas Schlatzer Pd-Mediated Allylation of Cysteine for Site-Selective Bioconjugation of Peptides and Proteins Show publication in PURE

Rolf Breinbauer and Thomas Schlatzer Palladium-Mediated Allylation of Cysteine for Site-Selective Bioconjugation Show publication in PURE

Rolf Breinbauer and Christian Lembacher-Fadum Total Syntheses of Tilivalline and Tilimycin, Cytotoxic Secondary Metabolites of <i>Klebsiella Oxytoca</i> Show publication in PURE

Rolf Breinbauer Development of Small-Molecule Inhibitors of Adipose Triglyceride Lipase (ATGL) Show publication in PURE

Rolf Breinbauer Synthesis and Biological Characterization of Teraryl-based alpha-Helix-Mimetics Show publication in PURE

Rolf Breinbauer and Thomas Schlatzer Palladium-Mediated Allylation of Cysteine for Site-Selective Bioconjugation Show publication in PURE

2017

Book Chapter

Rolf Breinbauer Comparative Activity-Based Flavin-Dependent Oxidase ProfilingMethods in Molecular Biology87-99 Show publication in PURE

Journal Article

Rolf Breinbauer Sequential and iterative Pd-catalyzed cross-coupling reactions in organic synthesis Monatshefte für Chemie - Chemical Monthly 148, 3-35, 2017 Show publication in PURE

Hansjörg Weber and Rolf Breinbauer Additive-Free Pd-Catalyzed α-Allylation of Imine-Containing Heterocycles Organic letters 19, 126-129, 2017 Show publication in PURE

Rolf Breinbauer Recent developments in the isolation, biological function, biosynthesis, and synthesis of phenazine natural products Bioorganic & Medicinal Chemistry 25, 6149-6166, 2017 Show publication in PURE

Rolf Breinbauer Synthesis of α,β-unsaturated aldehydes as potential substrates for bacterial luciferases Bioorganic & Medicinal Chemistry 25, 1487-1495, 2017 Show publication in PURE

Rolf Breinbauer Festphasen- und Flowsynthese (Trendbericht Organische Chemie 2016) Nachrichten aus der Chemie 65, 274-275, 2017 Show publication in PURE

Rolf Breinbauer Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice Nature Communications 8, 2017 Show publication in PURE

Hansjörg Weber and Rolf Breinbauer Mechanisms and Specificity of Phenazine Biosynthesis Protein PhzF Scientific Reports 7, 2017 Show publication in PURE

Rolf Breinbauer and Christian Lembacher-Fadum Biosynthesis of the Enterotoxic Pyrrolobenzodiazepine Natural Product Tilivalline Angewandte Chemie / International Edition 56, 14753–14757, 2017 Show publication in PURE

Rolf Breinbauer and Christian Lembacher-Fadum Biosynthese des enterotoxischen Pyrrolobenzodiazepin-Naturstoffs Tilivallin Angewandte Chemie 129, 14948–14952, 2017 Show publication in PURE

Rolf Breinbauer C-H and C-C bond insertion reactions of diazo compounds into aldehydes Tetrahedron 73, 6815-6829, 2017 Show publication in PURE

Other Article

Rolf Breinbauer, Christian Lembacher-Fadum and Thomas Schlatzer Post-Translational Pd-Catalyzed S-Prenylation of Peptides and Proteins Show publication in PURE

Hansjörg Weber, Rolf Breinbauer and Christian Lembacher-Fadum Investigation of an Unexpected Cyclization During a Horner-Wadsworth-Emmons Reaction Show publication in PURE

Rolf Breinbauer New Palladium Catalyzed Approach towards 5-membered Nitrogen-containing Heterocycles Show publication in PURE

Rolf Breinbauer A General and Direct Reductive Amination of Aldehydes and Ketones with Electron-Deficient Anilines Show publication in PURE

Rolf Breinbauer Kinetic studies of inhibition of hDPP3 by hydroxyethylene transition state peptidomimetics Show publication in PURE

Rolf Breinbauer Peptidomimetic transition state inhibitors as chemical probes to explore in-vivo role of dipeptidyl peptidase 3 Show publication in PURE

Rolf Breinbauer Stabilization of a cancer associated variant of human NQO1 by the use of small-molecular chaperones Show publication in PURE

Rolf Breinbauer Rescuing the stability and activity of a cancer associated variant of human NQO1 by small molecular chaperones Show publication in PURE

Rolf Breinbauer Pharmacological inhibition of ATGL (Adipose Triglyceride Lipase) corrects high-fat diet-induced hepatosteatosis in mice Show publication in PURE

Rolf Breinbauer Substrate specificity of CYP505X from Aspergillus fumigatus Show publication in PURE

Rolf Breinbauer Pharmacological Inhibition of Adipose Triglyceride Lipase corrects High-Fat Diet-Induced Insulin Resistance and Hepatosteatosis in mice Show publication in PURE

Rolf Breinbauer Synthesis of an Amphiphilic Oligoaryl-based ApoA1 Mimetic Show publication in PURE

Rolf Breinbauer New “old yellow enzyme”: a reductive C-C bond formation using engineered enoate reductase Show publication in PURE

Rolf Breinbauer Chemoenzymatic Synthesis of α-Quaternary Stereogenic α-Amino Acids Show publication in PURE

Rolf Breinbauer Development of small-molecule inhibitors of Adipose Triglyceride Lipase (ATGL) Show publication in PURE

Rolf Breinbauer Chemoenzymatic Synthesis of α-Quaternary Stereogenic α-Amino Acids Show publication in PURE

2016

Book Chapter

Rolf Breinbauer Reductions of Carboxylic Acids and DerivativesOrganic Electrochemistry1249-1265 Show publication in PURE

Rolf Breinbauer Future Directions of Modern Organic SynthesisFrom Biosynthesis to Total Synthesis: Strategies and Tactics for Natural Products519 Show publication in PURE

Journal Article

Rolf Breinbauer Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p Biochimica et Biophysica Acta 1861, 462, 2016 Show publication in PURE

Rolf Breinbauer and Wolfgang Kroutil Characterization of the monolignol oxidoreductase AtBBE-like protein 15 L182V for biocatalytic applications Journal of molecular catalysis / B 133, S6-S14, 2016 Show publication in PURE

Rolf Breinbauer Aus zwei mach eins: die Biosynthese der Phenazine Biospektrum 22, 137-139, 2016 Show publication in PURE

Rolf Breinbauer Festphasen- und Flowsynthese (Trendbericht, Organische Chemie 2015) Nachrichten aus der Chemie 64, 262-263, 2016 Show publication in PURE

Rolf Breinbauer Chemical Genetic Approaches for the Investigation of Neutral Lipid Metabolism ChemBioChem 17, 358 – 377, 2016 Show publication in PURE

Rolf Breinbauer Improved and Scalable Synthesis of Building Blocks for the Modular Synthesis of Teraryl-based alpha-Helix Mimetics Monatshefte für Chemie - Chemical Monthly 147, 509-521, 2016 Show publication in PURE

Rolf Breinbauer Enzymatic hydrolysis of poly(ethylene furanoate) Journal of Biotechnology 235, 47-53, 2016 Show publication in PURE

Rolf Breinbauer A General and Direct Reductive Amination of Aldehydes and Ketones with Electron-Deficient Anilines Synthesis 48, 1301-1307, 2016 Show publication in PURE

Rolf Breinbauer Tracking protein S-fatty acylation with proteomics ChemBioChem 17, 1488-1490, 2016 Show publication in PURE

Rolf Breinbauer Target identification of small molecule drugs and chemical probes Bioorganic & Medicinal Chemistry 24, 3231-3231, 2016 Show publication in PURE

Rolf Breinbauer Target identification of covalently binding drugs by activity-based protein profiling (ABPP) Bioorganic & Medicinal Chemistry 24, 3291-3303, 2016 Show publication in PURE

Other Article

Rolf Breinbauer Development of small-molecule inhibitors targeting adipose triglyceride lipase (ATGL) Show publication in PURE

Rolf Breinbauer A General and Direct Reductive Amination of Aldehydes and Ketones with Electron-Deficient Anilines Show publication in PURE

Rolf Breinbauer New “old yellow enzyme”: Reductive C-C bond formation using an engineered enoate reductase Show publication in PURE

Rolf Breinbauer A Modular Synthesis of an Amphiphilic Oligoaryl-based ApoA1 Mimetic as a Potential Drug Carrier Show publication in PURE

Rolf Breinbauer Modular Synthesis of Teraryl-based alpha-Helix-Mimetics for the Inhibition of Protein-Protein-Interactions Show publication in PURE

Rolf Breinbauer Modular Synthesis of Teraryl-based alpha-Helix-Mimetics Show publication in PURE

Rolf Breinbauer Novel insights into structural destabilization of a cancer associated variant of human NQO1 Show publication in PURE

Rolf Breinbauer Expression of fungal cytochrome P450 variants in E. coli and their validation for API metabolite synthesis Show publication in PURE

Rolf Breinbauer Role of enzymes involved in Bacterial Bioluminescence Show publication in PURE

Rolf Breinbauer Towards API Metabolite Synthesis by Fungal Cytochrome P450 variants Show publication in PURE

Rolf Breinbauer Characterization and therapeutic exploitation of human dipeptidyl peptidase III (hDPPIII): an enzyme with multifaceted functionality Show publication in PURE

Rolf Breinbauer Targeting human dipeptidyl peptidase III (hDPPIII): a therapeutic potential for safer pain management Show publication in PURE

Rolf Breinbauer Towards understanding the structural destabilization of a cancer associated variant of human NQO1 Show publication in PURE

Rolf Breinbauer On the way to rescue the stability and activity of a cancer associated variant of human NQO1 Show publication in PURE

Rolf Breinbauer An Additive-Free Approach for the Alpha-Allylation of Nitrogen Heterocycles Show publication in PURE

2015

Journal Article

Rolf Breinbauer Adiose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of the hepatic stellate cells Biochimica et Biophysica Acta 1851, 937-945, 2015 Show publication in PURE

Rolf Breinbauer Structure-activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL) Bioorganic & Medicinal Chemistry 23, 2904-2916, 2015 Show publication in PURE

Rolf Breinbauer and Christian Lembacher-Fadum A rapid and efficient one-pot method for the reduction of N-protected alpha-amino acids to chiral alpha-amino aldehydes using CDI/DIBAL-H Organic & biomolecular chemistry 13, 10456-10460, 2015 Show publication in PURE

Rolf Breinbauer Weighing the Proteasome for Covalent Modifications Chemistry & Biology 22, 315-316, 2015 Show publication in PURE

Rolf Breinbauer and Carina Illaszewicz-Trattner A robust and simple protocol for the synthesis of arylfluorophosphonates Tetrahedron letters 56, 5619-5622, 2015 Show publication in PURE

Rolf Breinbauer Expanding the threonine aldolase toolbox for the asymmetric synthesis of tertiary α-amino acids Applied Microbiology and Biotechnology 99, 9651-9661, 2015 Show publication in PURE

Rolf Breinbauer Festphasen- und Flowsynthese (Trendberichte Organische Chemie 2014) Nachrichten aus der Chemie 63, 273-273, 2015 Show publication in PURE

Hansjörg Weber and Rolf Breinbauer Biocatalyzed approach for the surface functionalization of poly(L-lactic acid) films using hydrolytic enzymes Biotechnology Journal 10, 1739-1749, 2015 Show publication in PURE

Hansjörg Weber and Rolf Breinbauer Diversity-Oriented Synthesis of a Library of Star-Shaped 2H-Imidazolines ACS Combinatorial Science 17, 682-690, 2015 Show publication in PURE

Rolf Breinbauer Fatty acid-binding proteins interact with comparative gene identification-58 linking lipolysis with lipid ligand shuttling The Journal of Biological Chemistry 290, 18438-18453, 2015 Show publication in PURE

Other Article

Rolf Breinbauer A modular synthesis of teraryl-based α-helix mimetics for inhibition of protein-protein interactions Show publication in PURE

Rolf Breinbauer Development of Inhibitors of PhzE - A New Target for Antibiotic Intervention Show publication in PURE

Rolf Breinbauer Design and Synthesis of Inhibitors of DPP3 Show publication in PURE

Rolf Breinbauer The mystery of myrFMN production by bioluminescent bacteria Show publication in PURE

Rolf Breinbauer The role of luciferase in myrFMN formation Show publication in PURE

Rolf Breinbauer A Base- and Additive-Free Approach of the Tsuji-Trost Reaction for the Synthesis of N-Heterocycles Show publication in PURE

Rolf Breinbauer Design and Synthesis of Inhibitors of Dipeptidyl Peptidase-III Show publication in PURE

Rolf Breinbauer Iterative Suzuki-Coupling for the Synthesis of an Amphiphilic Oligoaryl-based ApoA1 Mimetic as a Potential Drug Carrier Show publication in PURE

Rolf Breinbauer Characterization and therapeutic potential of DPP III knockout mice Show publication in PURE

Rolf Breinbauer NAD( P)H:quinone oxidoreductase 1 as a crucial enzyme in human cancer development and treatment Show publication in PURE

Rolf Breinbauer and Christian Lembacher-Fadum Design and Synthesis of Inhibitors of Dipeptidyl Peptidase-III Show publication in PURE

Rolf Breinbauer Synthesis of chemical probes to investigate the Mechanism of PhzA/B Show publication in PURE

Rolf Breinbauer Structure-Based Design and Synthesis of Inhibitors of Dipeptidylpeptidase III (DPP3) Show publication in PURE

Rolf Breinbauer The mystery of myrFMN production by bioluminescent bacteria Show publication in PURE

Rolf Breinbauer NAD(P)H:quinone oxidoreductase 1 as a crucial enzyme in human cancer development and treatment Show publication in PURE

Rolf Breinbauer Discovery and Characterization of Atglistatin – The First Inhibitor of ATGL (Adipose Triglyzeride Lipase) Show publication in PURE

Rolf Breinbauer Synthesis of chemical probes to investigate the Mechanism of PhzA/B Show publication in PURE

Rolf Breinbauer A luciferous surprise: A new natural aldehyde substrate for bacterial bioluminescence Show publication in PURE

Rolf Breinbauer NAD(P)H:quinone oxidoreductase 1 as a crucial enzyme in human cancer development and treatment Show publication in PURE

Rolf Breinbauer A modular synthesis of teraryl-based alpha-helix mimetics for inhibition of protein-protein-interactions Show publication in PURE

Rolf Breinbauer Threonine Aldolases as Catalysts for the Synthesis of a-Quaternary a-Amino Acids Show publication in PURE

2014

Book Chapter

Rolf Breinbauer Enzymes in Organic SynthesisKirk-Othmer Encyclopedia1-43 Show publication in PURE

Journal Article

Rolf Breinbauer Stereochemistry and Mechanism of Enzymatic and Non-Enzymatic Hydrolysis of Benzylic sec-Sulfate Esters European Journal of Organic Chemistry 2014, 3930-3934, 2014 Show publication in PURE

Rolf Breinbauer Festphasensynthese (Trendberichte Organische Chemie 2013) Nachrichten aus der Chemie 62, 273-274, 2014 Show publication in PURE

Rolf Breinbauer More than just a halogenase: modification of fatty acyl moieties by a trifunctional metal enzyme ChemBioChem 15, 567-574, 2014 Show publication in PURE

Hansjörg Weber and Rolf Breinbauer Towards the synthesis of glycosylated dihydrochalcone natural products using glycosyltransferase-catalysed cascade reactions Green Chemistry 16, 4417-4425, 2014 Show publication in PURE

Rolf Breinbauer Recent advances and applications of reductive desulfurization in organic synthesis Tetrahedron 70, 8983-9027, 2014 Show publication in PURE

Hansjörg Weber and Rolf Breinbauer Enterotoxicity of a nonribosomal peptide causes antibiotic-associated colitis Proceedings of the National Academy of Sciences of the United States of America 111, 13181-13186, 2014 Show publication in PURE

Rolf Breinbauer The Development of a Modular Synthesis of Teraryl-based alpha-Helix Mimetics as Potential Inhibitors of Protein-Protein Interactions Synlett 25, 1202-1214, 2014 Show publication in PURE

Rolf Breinbauer Biosynthese der Phenazine Nachrichten aus der Chemie 62, 975-980, 2014 Show publication in PURE

Rolf Breinbauer Exploring the new threonine aldolases with broad donor specificity New Biotechnology 31, S87-S87, 2014 Show publication in PURE

Other Article

Rolf Breinbauer A Modular Approach for the Synthesis of Teraryls – a-Helix Mimetics for the Inhibition of Protein-Protein-Interactions Show publication in PURE

Rolf Breinbauer Synthesis of chemical probes to investigate the mechanism of PhzA/B Show publication in PURE

Rolf Breinbauer Racemization-Free Chemoenzymatic Peptide Synthesis Enabled via a Combination of Transition Metal and Enzyme Catalysis Show publication in PURE

Rolf Breinbauer A Modular Synthesis of Teraryl-based α-Helix Mimetics for the Inhibition of Protein-Protein-Interactions Show publication in PURE

Rolf Breinbauer A Modular Synthesis of an Amphiphilic Oligoaryl-based ApoA1 Mimetic as a Potential Drug Carrier Show publication in PURE

Rolf Breinbauer Diversity-Oriented Synthesis of a 2H-Imidazolidine Library Show publication in PURE

Rolf Breinbauer Exploring the new Threonine Aldolases with broad donor specificity Show publication in PURE

Rolf Breinbauer Synthesis of chemical probes to investigate the mechanism of PhzA/B Show publication in PURE

2013

Journal Article

Rolf Breinbauer Development of small molecule inhibitors for adipose triglyceride lipase Nature Chemical Biology 9, 785-787, 2013 Show publication in PURE

Rolf Breinbauer Investigation of one-enzyme systems in the ω-transaminase-catalyzed synthesis of chiral amines Journal of molecular catalysis / B 96, 103-110, 2013 Show publication in PURE

Rolf Breinbauer Development of small-molecule inhibitors targeting adipose triglyceride lipase Nature Chemical Biology 9, 785-787, 2013 Show publication in PURE

Rolf Breinbauer Chemical Synthesis of Hormones, Pheromones and Other Bioregulators (by K. Mori) Synthesis 45, 978-978, 2013 Show publication in PURE

Rolf Breinbauer It takes two to tango: Klebsiella oxytoca overgrowth and production of Tilivalline, a cytotoxin, are the key events causing Antibiotic-Associated Hemorrhagic Colitis Zeitschrift für Gastroenterologie 51, A50-A50, 2013 Show publication in PURE

Rolf Breinbauer A Modular Synthesis of Teraryl-Based α-Helix Mimetics, Part 2: Synthesis of 5-Pyridine Boronic Acid Pinacol Ester Building Blocks with Amino Acid Side Chains in 3-Position Chemistry - a European Journal 19, 2450-2456, 2013 Show publication in PURE

Rolf Breinbauer A Modular Synthesis of Teraryl based alpha-Helix Mimetics, Part 1: Synthesis of Core Fragments with two Electronically Differentiated Leaving Groups Chemistry - a European Journal 19, 2442-2449, 2013 Show publication in PURE

Rolf Breinbauer Festphasensynthese (Trendberichte Organische Chemie 2012) Nachrichten aus der Chemie 61, 280-281, 2013 Show publication in PURE

Rolf Breinbauer Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase The Journal of Biological Chemistry 288, 31093-31104, 2013 Show publication in PURE

Rolf Breinbauer Investigation of one-enzyme systems in the w-transaminase-catalyzed synthesis of chiral amines Journal of molecular catalysis / B 96, 103-110, 2013 Show publication in PURE

Rolf Breinbauer Racemization-Free Chemoenzymatic Peptide Synthesis Enabled by the Ruthenium-Catalyzed Synthesis of Peptide Enol Esters via Alkyne-Addition and Subsequent Conversion Using Alcalase-Cross-Linked Enzyme Aggregates Advanced Synthesis & Catalysis 355, 1799-1807, 2013 Show publication in PURE

Rolf Breinbauer Investigation of the origin and synthetic application of the pseudodilution effect for Pd-catalyzed macrocyclisations in concentrated solutions with immobilized catalysts Organic & biomolecular chemistry 11, 4750-4756, 2013 Show publication in PURE

Other Article

Rolf Breinbauer Phenazine Biosynthesis - Novel Enzyme Mechanism in Nature? Show publication in PURE

Rolf Breinbauer Design and synthesis of inhibitors of dipeptidyl peptidase-III Show publication in PURE

Rolf Breinbauer A Modular Synthesis of Teraryl-based α-Helix Mimetics for the Inhibition of Protein-Protein-Interactions Show publication in PURE

Rolf Breinbauer Discovery and Characterization of Atglistatin – The First Inhibitor of ATGL (Adipose Triglyzeride Lipase) Show publication in PURE

Rolf Breinbauer ACIB and CHEM21: Towards greener and more sustainable pharmaceutical manufacturing processes Show publication in PURE

Rolf Breinbauer Racemization-Free Chemoenzymatic Peptide Synthesis via a Combination of Transition Metal and Enzyme Catalysis Show publication in PURE

Rolf Breinbauer Development of Inhibitors of PhzE- A New Target for Antibiotic Intervention Show publication in PURE

Rolf Breinbauer A Modular Synthesis of Teraryl-based α-Helix Mimetics for the Inhibition of Protein-Protein-Interactions Show publication in PURE

Rolf Breinbauer Design and synthesis of inhibitors of dipeptidyl peptidase-III Show publication in PURE

Rolf Breinbauer Synthesis of chemical probes to investigate the mechanism of PhzA/B Show publication in PURE

Rolf Breinbauer Investigation of the palladium catalyzed C-allylation of phenols Show publication in PURE

Rolf Breinbauer Biocatalytic access to a,a-dialkyl-a-amino acids Show publication in PURE

Rolf Breinbauer Pd-Catalyzed Allylation – a Powerful Tool for Post-Translational Modification of Proteins Show publication in PURE

Rolf Breinbauer Diversity-Oriented Synthesis of a 2H-Imidazolidine Library Show publication in PURE

2012

Book Chapter

Rolf Breinbauer Activity-Based Protein Profiling for Natural Product Target DiscoveryTopics Current Chemistry43-84 Show publication in PURE

Journal Article

Rolf Breinbauer An efficient labelling strategy of drug like molecules with functionalized alkyl linkers using CH-activation Chemical Communications 48, 10343-10345, 2012 Show publication in PURE

Rolf Breinbauer Festphasensynthese (Trendberichte Organische Chemie 2011) Nachrichten aus der Chemie 60, 286-286, 2012 Show publication in PURE

Rolf Breinbauer Activity-Based Probes for Studying the Activity of Flavin-Dependent Oxidases and for the Protein Target Profiling of Monoamine Oxidase Inhibitors Angewandte Chemie / International Edition 51, 7035-7040, 2012 Show publication in PURE

Rolf Breinbauer Aktivitätsbasierte Sondenmoleküle zur Untersuchung der Aktivität Flavin-abhängiger Oxidasen und zum Zielprotein-Profiling von Monoaminooxidase-Inhibitoren Angewandte Chemie 124, 7142-7147, 2012 Show publication in PURE

Other Article

Rolf Breinbauer Novel activity-based probes for studying the activity of flavin-dependent oxidases and for the protein target profiling of MAO-inhibitors Show publication in PURE

Rolf Breinbauer A Modular Approach for the Synthesis of Teraryls: a-Helix Mimetics for the Inhibition of Protein-Protein-Interaction Show publication in PURE

Rolf Breinbauer Novel activity-based probes for studying the activity of flavin-dependent oxidases and for the protein target profiling of MAO-inhibitors Show publication in PURE

2011

Journal Article

Rolf Breinbauer Festphasensynthese (Trendberichte Organische Chemie 2010) Nachrichten aus der Chemie 59, 275-275, 2011 Show publication in PURE

Rolf Breinbauer The Witkop–Winterfeldt oxidation converts tetrahydropyridoindoles into pyrroloquinolones and cinnolines by an unprecedented scaffold rearrangement Tetrahedron 67, 965-970, 2011 Show publication in PURE

Other Article

Rolf Breinbauer A Modular Approach for the Synthesis of Teraryl alpha-Helix Mimetics Show publication in PURE

Rolf Breinbauer Innovative Synthetic Approaches for Covalent Drug Immobilization Show publication in PURE

Rolf Breinbauer Synthetic stategies for the covalent immobilization of drug molecules Show publication in PURE

Rolf Breinbauer Novel pargyline-derived probes as effective proteomic tools for the active-site labelling of flavin-dependent oxidases Show publication in PURE

2010

Book Chapter

Rolf Breinbauer Combinatorial Chemistry and the Synthesis of Compound LibrariesLigand-Macromolecular Interactions in Drug Discovery: Methods and Protocols, Methods in Molecular Biology, Vol. 57273-80 Show publication in PURE

Journal Article

Rolf Breinbauer Preparation of Biomolecule Microstructures and Microarrays by Thiol-ene Photoimmobilization ChemBioChem 11, 235-247, 2010 Show publication in PURE

Rolf Breinbauer Festphasensynthese (Trendberichte Organische Chemie 2009) Nachrichten aus der Chemie 58, 282-282, 2010 Show publication in PURE

Rolf Breinbauer A simple synthesis of functionalized 3-methyl-1-pyridinyl-1H-imidazolium salts as bidentate N-heterocyclic-carbene precursors and their application in Ir-catalyzed arene borylation Tetrahedron letters 51, 6622-6625, 2010 Show publication in PURE

Other Article

Rolf Breinbauer Metalle verknüpfen Kohlenstoff - Chemienobelpreis 2010 Show publication in PURE

Rolf Breinbauer Towards an extension of chemical biology toolbox – design and synthesis of novel activity-based probes targeting flavin-dependent oxidases Show publication in PURE

Rolf Breinbauer Novel pargyline-derived probes as effective proteomic tools for the active-site labeling of monoamine oxidases Show publication in PURE

2009

Book Chapter

Rolf Breinbauer Solid-Phase Synthesis of BiomoleculesPost-translational modifications to regulate protein function to Xenobiotic metabolism354-361 Show publication in PURE

Rolf Breinbauer The Use of Photoaffinity Labeling for the Identification of the Binding Site of the Antibiotic LinezolidChemical Biology – Learning through Case Studies79-88 Show publication in PURE

Rolf Breinbauer The Introduction of Chemical Reporter Groups by Bioorthogonal Ligation Reactions for the Imaging of Cell-Surface GlycansChemical Biology – Learning through Case Studies221-232 Show publication in PURE

Journal Article

Rolf Breinbauer Of Two Make One: The Biosynthesis of Phenazines ChemBioChem 10, 2295-2304, 2009 Show publication in PURE

Rolf Breinbauer Gleichzeitige Bindung beider Enantiomere eines racemischen Wirkstoffs durch das aktive Zentrum eines Enzyms Angewandte Chemie 121, 9248-9251, 2009 Show publication in PURE

Rolf Breinbauer Polystyrolsulfonylchlorid – ein hochorthogonales Linkerharz für die Synthese von Stickstoffheterocyclen Angewandte Chemie 121, 5955-5958, 2009 Show publication in PURE

Rolf Breinbauer Polystyrene Sulfonyl Chloride: A Highly Orthogonal Linker Resin for the Synthesis of Nitrogen-Containing Heterocycles Angewandte Chemie / International Edition 48, 5841-5844, 2009 Show publication in PURE

Rolf Breinbauer An Environmentally Benign Electrochemical Process for the Reduction of Carboxylic Acid Hydrazides to Amides Synthesis 2009, 1463-1468, 2009 Show publication in PURE

Rolf Breinbauer The Power of Functional Resins (Eds.J. Tulla-Puche, F. Albericio) Angewandte Chemie / International Edition 48, 3560-3561, 2009 Show publication in PURE

Rolf Breinbauer Classics in Stereoselective Synthesis (By E. M. Carreira, L. Kvaerno) Synthesis 2009, 1760-1760, 2009 Show publication in PURE

Rolf Breinbauer The Active Site of an Enzyme Can Host Both Enantiomers of a Racemic Ligand Simultaneously Angewandte Chemie / International Edition 48, 9084-9087, 2009 Show publication in PURE

Rolf Breinbauer Festphasensynthese (Trendberichte Organische Chemie 2008) Nachrichten aus der Chemie 57, 266-266, 2009 Show publication in PURE

2008

Book

Rolf Breinbauer Neuberufungen - Rolf Breinbauer978-3-902465-96-2 Show publication in PURE

Journal Article

Rolf Breinbauer The Synthetic Organic Chemist’s Companion (by M.C. Pirrung) Synthesis 2008, 1486-1486, 2008 Show publication in PURE

Rolf Breinbauer Angewandte homogene Katalyse (by A. Behr) Synthesis 2008, 3012-3012, 2008 Show publication in PURE

Rolf Breinbauer The Way of Synthesis: Evolution of Design and Methods for Natural Products Synthesis 2008, 330-330, 2008 Show publication in PURE

Rolf Breinbauer PhzA/B Catalyzes the Formation of the Tricycle in Phenazine Biosynthesis Journal of the American Chemical Society 130, 17053-17061, 2008 Show publication in PURE

Rolf Breinbauer Festphasensynthese (Trendberichte Organische Chemie 2007) Nachrichten aus der Chemie 56, 286-287, 2008 Show publication in PURE

Rolf Breinbauer Photochemical Surface Patterning by Thiol-Ene Reaction Angewandte Chemie / International Edition 120, 4493-4496, 2008 Show publication in PURE

2007

Book Chapter

Rolf Breinbauer Reverse Chemical Genetics – An Important Strategy for the Study of Protein Function in Chemical Biology and Drug DiscoveryChemical Biology355-384 Show publication in PURE

Rolf Breinbauer Combinatorial Solid Phase Natural Product ChemistryTopics Current Chemistry209-241 Show publication in PURE

Journal Article

Rolf Breinbauer The Investigation of Organic Reactions and their Mechanisms Synthesis 2007, 1438-1438, 2007 Show publication in PURE

Rolf Breinbauer A Microarray Strategy for Mapping the Substrate Specificity of Protein Tyrosine Phosphatase Angewandte Chemie / International Edition 46, 7700-7703, 2007 Show publication in PURE

Rolf Breinbauer Organic Reactions in Water. Principles, Strategies, and Applications Synthesis 2007, 3094-3094, 2007 Show publication in PURE

Rolf Breinbauer The Witkop-Winterfeldt-Oxidation of Indoles Current organic chemistry 11, 159-176, 2007 Show publication in PURE

Rolf Breinbauer Domino Reactions in Organic Synthesis Synthesis 2007, 794-794, 2007 Show publication in PURE

Rolf Breinbauer Electrons as a Reagent in Solid-Phase Organic Synthesis European Journal of Organic Chemistry 2007, 4283-4292, 2007 Show publication in PURE

Rolf Breinbauer Festphasensynthesen (Trendbericht, Organische Chemie 2006) Nachrichten aus der Chemie 55, 266-267, 2007 Show publication in PURE

Other Article

Rolf Breinbauer Recent Research Highlights Show publication in PURE

2006

Journal Article

Rolf Breinbauer Electrolysis as an Efficient Key Step in the Homogeneous Polymer-Supported Synthesis of N-Substituted Pyrroles Organic letters 8, 403-406, 2006 Show publication in PURE

Rolf Breinbauer Festphasensynthesen (Trendbericht, Organische Chemie 2005) Nachrichten aus der Chemie 54, 245-245, 2006 Show publication in PURE

Rolf Breinbauer Site Selective Protein Immobilization by Staudinger-Ligation Angewandte Chemie / International Edition 45, 1408-1412, 2006 Show publication in PURE

Rolf Breinbauer A generic building block for C- and N-terminal protein-labeling and protein immobilization Bioorganic & Medicinal Chemistry 14, 6288-6306, 2006 Show publication in PURE

2005

Journal Article

Rolf Breinbauer Electroorganic Synthesis of 2,5-Dialkoxydihydrofurans and Pyridazines on Solid Phase using Polymer Beads as Supports Synthesis 2005, 3654-3665, 2005 Show publication in PURE

Rolf Breinbauer Solid-supported Reagents and Catalysts for the Preparation of Large Ring Compounds Molecular diversity 9, 51-62, 2005 Show publication in PURE

2004

Book Chapter

Rolf Breinbauer Small molecule arraysHighlights in Bioorganic Chemistry485-500 Show publication in PURE

Rolf Breinbauer Introduction: Chemical Biology – A New Science at the Crossroads of Chemistry and BiologyChemical Biology - A Practical Course1-15 Show publication in PURE

Journal Article

Rolf Breinbauer An efficient and inexpensive scavenger resin for Grubbs' catalyst Tetrahedron letters 45, 3141-3142, 2004 Show publication in PURE

Rolf Breinbauer The Staudinger Ligation - A Gift to Chemical Biology Angewandte Chemie / International Edition 43, 3106-3116, 2004 Show publication in PURE

Rolf Breinbauer Electroorganic Synthesis on Solid Phase using Polymer Beads as Supports Angewandte Chemie / International Edition 43, 2297-2299, 2004 Show publication in PURE

2003

Book Chapter

Rolf Breinbauer From Protein Domains to Drug Candidates – Natural Products as Guiding Principles in Compound Library Design and SynthesisSmall Molecule – Protein Interactions (Ernst Schering Research Foundation, Workshop 42167-188 Show publication in PURE

Journal Article

Rolf Breinbauer Protein Structure Similarity as Guiding Principle for Combinatorial Library Design Biological Chemistry 384, 1265-1272, 2003 Show publication in PURE

Rolf Breinbauer Chemical Genetics Goes (Zebra) Fishing Angewandte Chemie / International Edition 42, 1116-1118, 2003 Show publication in PURE

Rolf Breinbauer An easily accessible resin-supported palladium catalyst for Sonogashira coupling Synlett 2003, 1049-1051, 2003 Show publication in PURE

Rolf Breinbauer Azide-alkyne Coupling - A Powerful Reaction for Bioconjugate Chemistry ChemBioChem 4, 1147-1149, 2003 Show publication in PURE

Rolf Breinbauer Staudinger-Ligation: A new Immobilization Strategy for the Preparation of Small Molecule Arrays Angewandte Chemie / International Edition 42, 5830-5834, 2003 Show publication in PURE

2002

Book Chapter

Rolf Breinbauer Polymer-supported synthesis of non-oligomeric natural productsOrganic Synthesis Highlights V395-408 Show publication in PURE

Journal Article

Rolf Breinbauer From protein domains to drug candidates – natural products as guiding principles in Angewandte Chemie / International Edition 41, 2878-2890, 2002 Show publication in PURE

Rolf Breinbauer Natural Product Guided Compound Library Development Current Medicinal Chemistry 9, 2129-2145, 2002 Show publication in PURE

2001

Journal Article

Rolf Breinbauer Size-selective electrochemical preparation of surfactant-stabilized Pd- Ni- and Pt/Pd Chemistry - a European Journal 7, 1084-1094, 2001 Show publication in PURE

2000

Journal Article

Rolf Breinbauer Cooperative asymmetric catalysis with dendrimer bound [Co(salen)] catalysts Angewandte Chemie / International Edition 39, 3604-3607, 2000 Show publication in PURE

Rolf Breinbauer Nickel comes full cycle Science 287, 437-438, 2000 Show publication in PURE

1998

Journal Article

Rolf Breinbauer Nanostructured nickel-clusters as catalysts in [3+2]-cycloaddition reactions Tetrahedron 54, 1233-1240, 1998 Show publication in PURE

1996

Journal Article

Rolf Breinbauer Suzuki and Heck reactions catalyzed by preformed palladium clusters and palladium/ Tetrahedron letters 37, 4499-4502, 1996 Show publication in PURE

1995

Journal Article

Rolf Breinbauer A new strategy in heterogenous catalysis: the design of cortex-catalysts Angewandte Chemie / International Edition 34, 2728-2730, 1995 Show publication in PURE