2022
Journal Article
Melanie Trobe, Martin Vareka, Till Schreiner, Patrick Simon Dobrounig, Carina Julia Doler, Ella Blessing Holzinger, Andreas Steinegger and Rolf Breinbauer A Modular Synthesis of Teraryl-Based α-Helix Mimetics, Part 3 European Journal of Organic Chemistry 2022, 2022 Show publication in PURE
Melanie Trobe, Julia Blesl, Martin Vareka, Till Schreiner and Rolf Breinbauer Modular Synthesis of Teraryl-based alpha-Helix Mimetics, Part 4: Core Fragments with two Halide Leaving Groups Featuring Side Chains of Proteinogenic Amino Acids European Journal of Organic Chemistry 2022, 2022 Show publication in PURE
Melanie Trobe, Till Schreiner, Martin Vareka, Sebastian Grimm, Bernhard Wölfl and Rolf Breinbauer A Modular Synthesis of Teraryl-based α-Helix Mimetics, Part 5: A Complete Set of Pyridine Boronic Acid Pinacol Esters Featuring Side Chains of Proteinogenic Amino Acids European Journal of Organic Chemistry 2022, 2022 Show publication in PURE
Gernot F Grabner, Nikolaus Guttenberger, Nicole Mayer, Anna K Migglautsch-Sulzer, Christian Lembacher-Fadum, Nermeen Fawzy, Dominik Bulfon, Peter Hofer, Thomas Züllig, Lennart Hartig, Natalia Kulminskaya, Gabriel Chalhoub, Margarita Schratter, Franz P W Radner, Karina Preiss-Landl, Sarah Masser, Achim Lass, Rudolf Zechner, Karl Gruber, Monika Oberer, Rolf Breinbauer and Robert Zimmermann Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes Journal of the American Chemical Society 144, 6237–6250, 2022 Show publication in PURE
Harald Podversnik, Shalinee Jha, Peter Macheroux and Rolf Breinbauer Design and synthesis of efficient fluororethylene-peptidomimetic inhibitors of dipeptidyl peptidase III (DPP3) Bioorganic and Medicinal Chemistry 67, 2022 Show publication in PURE
2021
Journal Article
Christoph Grininger, Mario Leypold, Philipp Aschauer, Tea Pavkov-Keller, Lina Riegler-Berket, Rolf Breinbauer and Monika Oberer Structural changes in the cap of rv0183/mtbmgl modulate the shape of the binding pocket Biomolecules 11, 2021 Show publication in PURE
Jakov Ivkovic, Shalinee Jha, Christian Lembacher-Fadum, Johannes Puschnig, Prashant Kumar, Viktoria Reithofer, Karl Gruber, Peter Macheroux and Rolf Breinbauer Efficient Entropy-Driven Inhibition of Dipeptidyl Peptidase III by Hydroxyethylene Transition-State Peptidomimetics Chemistry - a European Journal 27, 14108-14120, 2021 Show publication in PURE
Arne Thiele, Katja Luettges, Daniel Ritter, Niklas Beyhoff, Elia Smeir, Jana Grune, Julia S Steinhoff, Michael Schupp, Robert Klopfleisch, Michael Rothe, Nicola Wilck, Hendrik Bartolomaeus, Anna K Migglautsch, Rolf Breinbauer, Erin E Kershaw, Gernot F Grabner, Rudolf Zechner, Ulrich Kintscher and Anna Foryst-Ludwig Pharmacological inhibition of adipose tissue Adipose Triglyceride Lipase (ATGL) by Atglistatin prevents catecholamine-induced myocardial damage Cardiovascular Research , 2021 Show publication in PURE
Ronald A. Glabonjat, Maksym Kitsera, Katrin Unterhauser, Christian Lembacher-Fadum, Christoph Högenauer, Georg Raber, Rolf Breinbauer and Ellen L. Zechner Simultaneous quantification of enterotoxins tilimycin and tilivalline in biological matrices using HPLC high resolution ESMS2 based on isotopically 15N-labeled internal standards Talanta 222, 2021 Show publication in PURE
Shingo Takahara, Mourad Ferdaoussi, Nikola Srnic, Zaid H Maayah, Shubham Soni, Anna Katharina Migglautsch-Sulzer, Rolf Breinbauer, Erin E Kershaw and Jason R B Dyck Inhibition of ATGL in adipose tissue ameliorates isoproterenol-induced cardiac remodeling by reducing adipose tissue inflammation American Journal of Physiology - Heart and Circulatory Physiology 320, H432-H446, 2021 Show publication in PURE
Christian Lembacher-Fadum, Simon Gissing, Georg Pour and Rolf Breinbauer Total synthesis of the isoquinolinium metabolite ETM-204 of Trabectidin Monatshefte für Chemie - Chemical Monthly , 2021 Show publication in PURE
2020
Journal Article
Thomas Schlatzer, Hilmar Schröder, Melanie Trobe, Christian Lembacher-Fadum, Simon Stangl, Christoph Schlögl, Hansjörg Weber and Rolf Breinbauer Pd/BIPHEPHOS is an Efficient Catalyst for the Pd‐Catalyzed S‐Allylation of Thiols with High n‐Selectivity Advanced Synthesis & Catalysis 362, 331-336, 2020 Show publication in PURE
Martin Vareka, Benedikt Dahms, Mario Lang, Minh Hao Hoang, Melanie Trobe, Hansjörg Weber, Maximilian H. Hielscher, Siegfried R. Waldvogel and Rolf Breinbauer Synthesis of a Bcl9 Alpha-Helix Mimetic for Inhibition of PPIs by a Combination of Electrooxidative Phenol Coupling and Pd-Catalyzed Cross Coupling Catalysts 10, 2020 Show publication in PURE
Rolf Breinbauer Festphasen- und Flowsynthese (Trendbericht, Organische Chemie 2019) Nachrichten aus der Chemie 68, 48-49, 2020 Show publication in PURE
Carina Doler, Michael Friess, Florian Lackner, Hansjörg Weber, Roland C. Fischer and Rolf Breinbauer Stereoselective synthesis of chiral thiol-containing 1,2-aminoalcohols via SmI2-mediated coupling Tetrahedron 76, 2020 Show publication in PURE
Nicole Mayer, Martina Schweiger, Elisabeth Fuchs, Anna K. Migglautsch, Carina Doler, Gernot F. Grabner, Matthias Romauch,, Michaela Christina Melcher, Rudolf Zechner, Robert Zimmermann and Rolf Breinbauer Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL) Bioorganic and Medicinal Chemistry 28, 2020 Show publication in PURE
Other Article
Thomas Schlatzer, Julia Kriegesmann, Christian F. W. Becker and Rolf Breinbauer Site-Selective Bioconjugation via Palladium-Mediated Allylation of Cysteine Show publication in PURE
2019
Journal Article
Marko Kljajic, Thomas Schlatzer and Rolf Breinbauer Synthesis of 2-Pyrrolidinones by Palladium-Catalyzed [3+2] Cycloaddition of Isocyanates Synlett 30, 581-585, 2019 Show publication in PURE
Benedikt Dahms, Philipp J. Kohlpaintner, Anton Wiebe, Rolf Breinbauer, Dieter Schollmeyer and Siegfried R. Waldvogel Selective Formation of 4,4′-Biphenols by Anodic Dehydrogenative Cross- and Homo-Coupling Reaction Chemistry - a European Journal 25, 2713-2716, 2019 Show publication in PURE
Rolf Breinbauer Festphasen- und Flowsynthese (Trendbericht, Organische Chemie 2018) Nachrichten aus der Chemie 67, 53-54, 2019 Show publication in PURE
Katrin Unterhauser, Lisa Pöltl, Georg Schneditz, Sabine Kienesberger, Ronald A. Glabonjat, Maksym Kitsera, Jakob Pletz, Fernando Josa-Prado, Elisabeth Dornisch, Christian Lembacher-Fadum, Sandro Roier, Gregor Gorkiewicz, Daniel Lucena, Isabel Barasoain, Wolfgang Kroutil, Marc Wiedner, Joanna I. Loizou, Rolf Breinbauer, José Fernando Díaz, Stefan Schild, Christoph Högenauer and Ellen L. Zechner Klebsiella oxytoca enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities Proceedings of the National Academy of Sciences of the United States of America 116, 3774-3783, 2019 Show publication in PURE
Gernot F. Grabner, Nermeen Fawzy, Maria A. Pribasnig, Markus Trieb, Ulrike Taschler, Michael Holzer, Martina Schweiger, Heimo Wolinski, Dagmar Kolb, Angela Horvath, Rolf Breinbauer, Thomas Rülicke, Roland Rabl, Achim Lass, Vanessa Stadlbauer, Birgit Hutter-Paier, Rudolf E. Stauber, Peter Fickert, Rudolf Zechner, Gunther Marsche, Thomas O. Eichmann and Robert Zimmermann Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans Journal of Lipid Research 60, 1020-1031, 2019 Show publication in PURE
Thomas Schlatzer, Julia Kriegesmann, Hilmar Schröder, Melanie Trobe, Christian Lembacher-Fadum, Simone Santner, Alexander Kravchuk, Christian F. W. Becker and Rolf Breinbauer Labeling and Natural Post-Translational Modification of Peptides and Proteins via Chemoselective Pd-Catalyzed Prenylation of Cysteine Journal of the American Chemical Society 141, 14931-14937, 2019 Show publication in PURE
Other Article
Melissa Willim, Thorsten Bachler, Bettina Schweda, Anna Katharina Migglautsch, Anton Glieder, Rolf Breinbauer and Margit Winkler Capsaicin Metabolite Synthesis by Fungal Cytochrome P450 Show publication in PURE
Marko Kljajic, Barbara Darnhofer, Matthias Schittmayer, Alexander Kollau, Bernhard Mayer, Ruth Birner-Grünberger and Rolf Breinbauer Iodonium-based Probes for the Activity-based Protein Profiling of Oxidoreductases Show publication in PURE
Thomas Schlatzer, Julia Kriegesmann, Christian F. W. Becker and Rolf Breinbauer Chemoselective Cysteine Bioconjugation via Palladium-Mediated Allylation Show publication in PURE
Rolf Breinbauer, Marko Kljajic, Barbara Darnhofer, Matthias Schittmayer, Alexander Kollau, Bernhard Mayer and Ruth Birner-Grünberger Iodonium-based Probes for the Activity-based Protein Profiling of Oxidoreductases Show publication in PURE
Thomas Schlatzer, Julia Kriegesmann, Christian F. W. Becker and Rolf Breinbauer Site-Selective Bioconjugation via Palladium-Mediated Allylation of Cysteine Show publication in PURE
Anna Katharina Migglautsch, Nikolaus Guttenberger, Martina Schweiger, Gernot F. Grabner, Nicole Mayer, R. Zechner, Robert Zimmermann and Rolf Breinbauer Development of Small-molecule inhibitors of Adipose Triglyceride Lipase (ATGL) Show publication in PURE
2018
Journal Article
Nirmal Parajuli, Shingo Takahara, Nobutoshi Matsumura, Ty T Kim, Mourad Ferdaoussi, Anna K Migglautsch, Rudolf Zechner, Rolf Breinbauer, Erin E Kershaw and Jason R B Dyck Atglistatin ameliorates functional decline in heart failure via adipocyte-specific inhibition of adipose triglyceride lipase American Journal of Physiology - Heart and Circulatory Physiology 315, H879-H884, 2018 Show publication in PURE
Julia Blesl, Melanie Trobe, Felix Anderl, Rolf Breinbauer, Gernot A. Strohmeier and Kateryna Fesko Application of Threonine Aldolases for the Asymmetric Synthesis of α-Quaternary α-Amino Acids ChemCatChem 10, 3453-3458, 2018 Show publication in PURE
Nikolaus Guttenberger, Thomas Schlatzer, Mario Leypold, Sebastian Tassoti and Rolf Breinbauer Synthesis of novel ligands targeting phenazine biosynthesis proteins as a strategy for antibiotic intervention Monatshefte für Chemie - Chemical Monthly 149, 847-856, 2018 Show publication in PURE
Rolf Breinbauer Festphasen- und Flowsynthese (Trendbericht, Organische Chemie 2017) Nachrichten aus der Chemie 66, 256-257, 2018 Show publication in PURE
Kathrin Heckenbichler, Anna Katharina Schweiger, Lea Alexandra Brandner, Alexandra Binter, Marina Toplak, Peter Macheroux, Karl Gruber and Rolf Breinbauer Asymmetric Reductive Carbocyclization Using Engineered Ene Reductases Angewandte Chemie - International Edition 57, 7240 –7244, 2018 Show publication in PURE
Kathrin Heckenbichler, Anna Katharina Schweiger, Lea Alexandra Brandner, Alexandra Binter, Marina Toplak, Peter Macheroux, Karl Gruber and Rolf Breinbauer Asymmetrische reduktive Carbocyclisierung durch modifizierte En‐Reduktasen Angewandte Chemie 130, 7360-7364, 2018 Show publication in PURE
Philipp Aschauer, Robert Zimmermann, Rolf Breinbauer, Tea Pavkov-Keller and Monika Oberer The crystal structure of monoacylglycerol lipase from M. tuberculosis reveals the basis for specific inhibition Scientific Reports 8, 2018 Show publication in PURE
Anna Katharina Migglautsch, Melissa Willim, Bettina Schweda, Anton Glieder, Rolf Breinbauer and Margit Winkler Aliphatic hydroxylation and epoxidation of capsaicin by Cytochrome P450 CYP505X Tetrahedron 74, 6199-6204, 2018 Show publication in PURE
Other Article
Thomas Schlatzer, Julia Kriegesmann, Hilmar Schröder, Melanie Trobe, Christian Lembacher-Fadum, Christian F. W. Becker and Rolf Breinbauer Pd-Mediated Allylation of Cysteine for Site-Selective Bioconjugation of Peptides and Proteins Show publication in PURE
Thomas Schlatzer, Julia Kriegesmann, Christian F. W. Becker and Rolf Breinbauer Palladium-Mediated Allylation of Cysteine for Site-Selective Bioconjugation Show publication in PURE
Christian Lembacher-Fadum, Elisabeth Dornisch, Jakob Pletz, Ronald A. Glabonjat, Florian Martin, Margit Neger, Christoph Högenauer, Kevin A. Francesconi, Wolfgang Kroutil, Klaus Zangger, Ellen L. Zechner and Rolf Breinbauer Total Syntheses of Tilivalline and Tilimycin, Cytotoxic Secondary Metabolites of <i>Klebsiella Oxytoca</i> Show publication in PURE
Anna Katharina Migglautsch, Carina Julia Doler, Martina Schweiger, Nicole Mayer, Elisabeth Fuchs, Gernot Grabner, Matthias Romauch, Rudolf Zechner, Robert Zimmermann and Rolf Breinbauer Development of Small-Molecule Inhibitors of Adipose Triglyceride Lipase (ATGL) Show publication in PURE
Julia Blesl, Martin Vareka, Melanie Trobe and Rolf Breinbauer Synthesis and Biological Characterization of Teraryl-based alpha-Helix-Mimetics Show publication in PURE
Thomas Schlatzer, Julia Kriegesmann, Christian F. W. Becker and Rolf Breinbauer Palladium-Mediated Allylation of Cysteine for Site-Selective Bioconjugation Show publication in PURE
Thomas Schlatzer, Julia Kriegesmann, Hilmar Schröder, Melanie Trobe, Christian F. W. Becker and Rolf Breinbauer Palladium-Mediated Allylation of Cysteine for Site-Selective Bioconjugation of Peptides and Proteins Show publication in PURE
2017
Book Chapter
Joanna Maria Krysiak and Rolf Breinbauer Comparative Activity-Based Flavin-Dependent Oxidase ProfilingMethods in Molecular Biology87-99 Show publication in PURE
Journal Article
Patrick Simon Dobrounig, Melanie Trobe and Rolf Breinbauer Sequential and iterative Pd-catalyzed cross-coupling reactions in organic synthesis Monatshefte für Chemie - Chemical Monthly 148, 3-35, 2017 Show publication in PURE
Marko Kljajic, Johannes G. Puschnig, Hansjörg Weber and Rolf Breinbauer Additive-Free Pd-Catalyzed α-Allylation of Imine-Containing Heterocycles Organic letters 19, 126-129, 2017 Show publication in PURE
Nikolaus Guttenberger, Wulf Blankenfeldt and Rolf Breinbauer Recent developments in the isolation, biological function, biosynthesis, and synthesis of phenazine natural products Bioorganic & Medicinal Chemistry 25, 6149-6166, 2017 Show publication in PURE
Eveline Brodl, Jakov Ivkovic, Chaitanya Tabib, Rolf Breinbauer and Peter Macheroux Synthesis of α,β-unsaturated aldehydes as potential substrates for bacterial luciferases Bioorganic & Medicinal Chemistry 25, 1487-1495, 2017 Show publication in PURE
Rolf Breinbauer Festphasen- und Flowsynthese (Trendbericht Organische Chemie 2016) Nachrichten aus der Chemie 65, 274-275, 2017 Show publication in PURE
Martina Schweiger, Matthias Romauch,, Renate Schreiber, Gernot Grabner, Sabrina Hütter, Petra Kotzbeck, Pia Benedikt, Thomas O. Eichmann, Sohsuke Yamada, Oskar Knittelfelder, Clemens Diwoky, Carina Julia Doler, Nicole Mayer, Werner De Cocco, Rolf Breinbauer, Robert Zimmermann and Rudolf Zechner Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice Nature Communications 8, 2017 Show publication in PURE
Christina Diederich, Mario Leypold, Martin Culka, Hansjörg Weber, Rolf Breinbauer, G. Matthias Ullmann and Wulf Blankenfeldt Mechanisms and Specificity of Phenazine Biosynthesis Protein PhzF Scientific Reports 7, 2017 Show publication in PURE
Elisabeth Dornisch, Jakob Pletz, Ronald A. Glabonjat, Florian Martin, Christian Lembacher-Fadum, Margit Neger, Christoph Högenauer, Kevin A. Francesconi, Wolfgang Kroutil, Klaus Zangger, Rolf Breinbauer and Ellen L. Zechner Biosynthesis of the Enterotoxic Pyrrolobenzodiazepine Natural Product Tilivalline Angewandte Chemie - International Edition 56, 14753–14757, 2017 Show publication in PURE
Elisabeth Dornisch, Jakob Pletz, Ronald A. Glabonjat, Florian Martin, Christian Lembacher-Fadum, Margit Neger, Christoph Högenauer, Kevin A. Francesconi, Wolfgang Kroutil, Klaus Zangger, Rolf Breinbauer and Ellen L. Zechner Biosynthese des enterotoxischen Pyrrolobenzodiazepin-Naturstoffs Tilivallin Angewandte Chemie 129, 14948–14952, 2017 Show publication in PURE
Nikolaus Guttenberger and Rolf Breinbauer C-H and C-C bond insertion reactions of diazo compounds into aldehydes Tetrahedron 73, 6815-6829, 2017 Show publication in PURE
Other Article
Shalinee Jha, Jakov Ivkovic, Prashant Kumar, Ulrike Taschler, Robert Zimmermann, Karl Gruber, Rolf Breinbauer and Peter Macheroux Kinetic studies of inhibition of hDPP3 by hydroxyethylene transition state peptidomimetics Show publication in PURE
Shalinee Jha, Jakov Ivkovic, Prashant Kumar, Ulrike Taschler, Robert Zimmermann, Karl Gruber, Rolf Breinbauer and Peter Macheroux Peptidomimetic transition state inhibitors as chemical probes to explore in-vivo role of dipeptidyl peptidase 3 Show publication in PURE
Emilia Sofia Strandback, Wolf-Dieter Lienhart, Altijana Hromic-Jahjefendic, Anja Högler, Daniel Waltenstorfer, Andreas Winkler, Klaus Zangger, Nadia Dandachi, Ellen Heitzer, Benjamin Bourgeois, Tobias Madl, Rolf Breinbauer, Karl Gruber and Peter Macheroux Stabilization of a cancer associated variant of human NQO1 by the use of small-molecular chaperones Show publication in PURE
Emilia Sofia Strandback, Wolf-Dieter Lienhart, Altijana Hromic-Jahjefendic, Anja Högler, Andreas Winkler, Klaus Zangger, Nadia Dandachi, Ellen Heitzer, Benjamin Bourgeois, Tobias Madl, Rolf Breinbauer, Karl Gruber and Peter Macheroux Rescuing the stability and activity of a cancer associated variant of human NQO1 by small molecular chaperones Show publication in PURE
Emilia Sofia Strandback, Wolf-Dieter Lienhart, Altijana Hromic-Jahjefendic, Anja Högler, Andreas Winkler, Klaus Zangger, Nadia Dandachi, Ellen Heitzer, Benjamin Bourgeois, Tobias Madl, Rolf Breinbauer, Karl Gruber and Peter Macheroux Rescuing the stability and activity of a cancer associated variant of human NQO1 by small molecular chaperones Show publication in PURE
Martina Schweiger, Nicole Mayer, Matthias Romauch,, Gernot Grabner, Carina Julia Doler, Anna Katharina Migglautsch, Sabrina Hütter, Petra Kotzbeck, Thomas O. Eichmann, Sohsuke Yamada, Oskar Knittelfelder, Clemens Diwoky, Achim Lass, Rudolf Zechner, Robert Zimmermann and Rolf Breinbauer Pharmacological inhibition of ATGL (Adipose Triglyceride Lipase) corrects high-fat diet-induced hepatosteatosis in mice Show publication in PURE
Thorsten Bachler, Anna Alkofer, Patrycja Gralewska, Astrid Weninger, Anton Glieder, Rolf Breinbauer and Margit Winkler Substrate specificity of CYP505X from Aspergillus fumigatus Show publication in PURE
Rolf Breinbauer, Carina Julia Doler, Martina Schweiger, Anna Katharina Migglautsch, Nicole Mayer, Gernot Grabner, Rudi Zechner and Robert Zimmermann Pharmacological Inhibition of Adipose Triglyceride Lipase corrects High-Fat Diet-Induced Insulin Resistance and Hepatosteatosis in mice Show publication in PURE
Patrick Simon Dobrounig and Rolf Breinbauer Synthesis of an Amphiphilic Oligoaryl-based ApoA1 Mimetic Show publication in PURE
Kathrin Heckenbichler, Anna Katharina Schweiger, Karl Gruber, Peter Macheroux and Rolf Breinbauer New “old yellow enzyme”: a reductive C-C bond formation using engineered enoate reductase Show publication in PURE
Julia Blesl, Gernot Strohmeier, Kateryna Fesko and Rolf Breinbauer Chemoenzymatic Synthesis of α-Quaternary Stereogenic α-Amino Acids Show publication in PURE
Anna Katharina Migglautsch, Carina Julia Doler, Martina Schweiger, Nicole Mayer, Elisabeth Fuchs, Gernot Grabner, Matthias Romauch,, Rudi Zechner, Robert Zimmermann and Rolf Breinbauer Development of small-molecule inhibitors of Adipose Triglyceride Lipase (ATGL) Show publication in PURE
Julia Blesl, Gernot Strohmeier, Kateryna Fesko and Rolf Breinbauer Chemoenzymatic Synthesis of α-Quaternary Stereogenic α-Amino Acids Show publication in PURE
Thomas Schlatzer, Hilmar Schröder, Melanie Trobe, Christian Lembacher-Fadum, Christian Becker and Rolf Breinbauer Post-Translational Pd-Catalyzed S-Prenylation of Peptides and Proteins Show publication in PURE
Christian Lembacher-Fadum, Jakov Ivkovic, Jakob Pletz, Karin Ratzenböck, Markus Maringer, Hansjörg Weber, Roland Fischer and Rolf Breinbauer Investigation of an Unexpected Cyclization During a Horner-Wadsworth-Emmons Reaction Show publication in PURE
Marko Kljajic and Rolf Breinbauer New Palladium Catalyzed Approach towards 5-membered Nitrogen-containing Heterocycles Show publication in PURE
Bernhard Berg, Jakob Pletz and Rolf Breinbauer A General and Direct Reductive Amination of Aldehydes and Ketones with Electron-Deficient Anilines Show publication in PURE
2016
Book Chapter
Rolf Breinbauer and Martin Peters Reductions of Carboxylic Acids and DerivativesOrganic Electrochemistry1249-1265 Show publication in PURE
Jakob Pletz and Rolf Breinbauer Future Directions of Modern Organic SynthesisFrom Biosynthesis to Total Synthesis: Strategies and Tactics for Natural Products519 Show publication in PURE
Journal Article
Melanie Trobe and Rolf Breinbauer Improved and Scalable Synthesis of Building Blocks for the Modular Synthesis of Teraryl-based alpha-Helix Mimetics Monatshefte für Chemie - Chemical Monthly 147, 509-521, 2016 Show publication in PURE
Alessandro Pellis, Karolina Haernvall, Christian Marco Pichler, G Ghazaryan, Rolf Breinbauer and Georg Gübitz Enzymatic hydrolysis of poly(ethylene furanoate) Journal of Biotechnology 235, 47-53, 2016 Show publication in PURE
Jakob Pletz, Bernhard Berg and Rolf Breinbauer A General and Direct Reductive Amination of Aldehydes and Ketones with Electron-Deficient Anilines Synthesis 48, 1301-1307, 2016 Show publication in PURE
Ruth Birner-Gruenberger and Rolf Breinbauer Tracking protein S-fatty acylation with proteomics ChemBioChem 17, 1488-1490, 2016 Show publication in PURE
Rolf Breinbauer Target identification of small molecule drugs and chemical probes Bioorganic & Medicinal Chemistry 24, 3231-3231, 2016 Show publication in PURE
Christian Marco Pichler, Joanna Maria Krysiak and Rolf Breinbauer Target identification of covalently binding drugs by activity-based protein profiling (ABPP) Bioorganic & Medicinal Chemistry 24, 3291-3303, 2016 Show publication in PURE
Philipp Aschauer, Srinivasan Rengachari, Jörg Lichtenegger, Matthias Schittmayer, K. M. Das, Nicole Mayer, Rolf Breinbauer, Ruth Birner-Grünberger, Christian C. Gruber, Robert Zimmermann, Karl Gruber and Monika Oberer Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p Biochimica et Biophysica Acta 1861, 462-470, 2016 Show publication in PURE
Sabine Pils, Kordula Schnabl, Silvia Wallner, Marko Kljajic, Nina Kupresanin, Rolf Breinbauer, Jörg Schrittwieser, Michael Fuchs, Wolfgang Kroutil, Bastian Daniel and Peter Macheroux Characterization of the monolignol oxidoreductase AtBBE-like protein 15 L182V for biocatalytic applications Journal of Molecular Catalysis B 133, S6-S14, 2016 Show publication in PURE
Christina Diederich, Mario Leypold, Rolf Breinbauer and Wulf Blankenfeldt Aus zwei mach eins: die Biosynthese der Phenazine Biospektrum 22, 137-139, 2016 Show publication in PURE
Rolf Breinbauer Festphasen- und Flowsynthese (Trendbericht, Organische Chemie 2015) Nachrichten aus der Chemie 64, 262-263, 2016 Show publication in PURE
Carina Julia Doler, Martina Schweiger, Robert Zimmermann and Rolf Breinbauer Chemical Genetic Approaches for the Investigation of Neutral Lipid Metabolism ChemBioChem 17, 358 – 377, 2016 Show publication in PURE
Other Article
Thorsten Bachler, Jörg Patrick-Rene Eichmann, Astrid Weninger, Anton Glieder, Rolf Breinbauer and Margit Winkler Towards API Metabolite Synthesis by Fungal Cytochrome P450 variants Show publication in PURE
Shalinee Jha, Ulrike Taschler, Jakov Ivkovic, Rolf Breinbauer, Karl Gruber, Robert Zimmermann and Peter Macheroux Characterization and therapeutic exploitation of human dipeptidyl peptidase III (hDPPIII): an enzyme with multifaceted functionality Show publication in PURE
Shalinee Jha, Jakov Ivkovic, Ulrike Taschler, Prashant Kumar, Robert Zimmermann, Karl Gruber, Rolf Breinbauer and Peter Macheroux Targeting human dipeptidyl peptidase III (hDPPIII): a therapeutic potential for safer pain management Show publication in PURE
Emilia Sofia Strandback, Wolf-Dieter Lienhart, Christoph Köberl, Altijana Hromic, Jakob Pletz, Venugopal Gudipati, Karl Gruber, Rolf Breinbauer and Peter Macheroux Towards understanding the structural destabilization of a cancer associated variant of human NQO1 Show publication in PURE
Emilia Sofia Strandback, Wolf-Dieter Lienhart, Christoph Köberl, Altijana Hromic, Jakob Pletz, Venugopal Gudipati, Klaus Zangger, Karl Gruber, Rolf Breinbauer and Peter Macheroux On the way to rescue the stability and activity of a cancer associated variant of human NQO1 Show publication in PURE
Marko Kljajic and Rolf Breinbauer An Additive-Free Approach for the Alpha-Allylation of Nitrogen Heterocycles Show publication in PURE
Carina Julia Doler, Anna Migglautsch, Nicole Mayer, Elisabeth Fuchs, Martina Schweiger, Matthias Romauch,, Gernot Grabner, Rudolf Zechner, Robert Zimmermann and Rolf Breinbauer Development of small-molecule inhibitors targeting adipose triglyceride lipase (ATGL) Show publication in PURE
Jakob Pletz, Bernhard Berg and Rolf Breinbauer A General and Direct Reductive Amination of Aldehydes and Ketones with Electron-Deficient Anilines Show publication in PURE
Kathrin Heckenbichler, Anna Katharina Schweiger, Alexandra Binter, Peter Macheroux, Karl Gruber and Rolf Breinbauer New “old yellow enzyme”: Reductive C-C bond formation using an engineered enoate reductase Show publication in PURE
Patrick Simon Dobrounig and Rolf Breinbauer A Modular Synthesis of an Amphiphilic Oligoaryl-based ApoA1 Mimetic as a Potential Drug Carrier Show publication in PURE
Melanie Trobe, Martin Peters, Sebastian Grimm, Bernhard Wölfl and Rolf Breinbauer Modular Synthesis of Teraryl-based alpha-Helix-Mimetics for the Inhibition of Protein-Protein-Interactions Show publication in PURE
Rolf Breinbauer, Melanie Trobe, Martin Peters, Sebastian Grimm and Bernhard Wölfl Modular Synthesis of Teraryl-based alpha-Helix-Mimetics Show publication in PURE
Emilia Sofia Strandback, Wolf-Dieter Lienhart, Altijana Hromic, Jakob Pletz, Christoph Köberl, Venugopal Gudipati, Karl Gruber, Rolf Breinbauer and Peter Macheroux Novel insights into structural destabilization of a cancer associated variant of human NQO1 Show publication in PURE
Thorsten Bachler, Jörg Patrick-Rene Eichmann, Astrid Weninger, Kerstin Hammer, Sanja Tunjic, Anton Glieder, Rolf Breinbauer and Margit Winkler Expression of fungal cytochrome P450 variants in E. coli and their validation for API metabolite synthesis Show publication in PURE
Eveline Brodl, Chaitanya Tabib, Jakov Ivkovic, Rolf Breinbauer and Peter Macheroux Role of enzymes involved in Bacterial Bioluminescence Show publication in PURE
2015
Journal Article
Ruth Birner-Gruenberger and Rolf Breinbauer Weighing the Proteasome for Covalent Modifications Chemistry & Biology 22, 315-316, 2015 Show publication in PURE
Mario Leypold, Paal W. Wallace, Marko Kljajic, Matthias Schittmayer, Jakob Pletz, Carina Illaszewicz-Trattner, Georg Gübitz, Ruth Birner-Grünberger and Rolf Breinbauer A robust and simple protocol for the synthesis of arylfluorophosphonates Tetrahedron letters 56, 5619-5622, 2015 Show publication in PURE
Kateryna Lypetska (Fesko), Gernot Strohmeier and Rolf Breinbauer Expanding the threonine aldolase toolbox for the asymmetric synthesis of tertiary α-amino acids Applied Microbiology and Biotechnology 99, 9651-9661, 2015 Show publication in PURE
Rolf Breinbauer Festphasen- und Flowsynthese (Trendberichte Organische Chemie 2014) Nachrichten aus der Chemie 63, 273-273, 2015 Show publication in PURE
Xuepu Yu, Nikolaus Guttenberger, Elisabeth Fuchs, Martin Peters, Hansjörg Weber and Rolf Breinbauer Diversity-Oriented Synthesis of a Library of Star-Shaped 2H-Imidazolines ACS Combinatorial Science 17, 682-690, 2015 Show publication in PURE
Alessandro Pellis, Enrique Herrero Acero, Hansjörg Weber, Michael Obersriebnig, Rolf Breinbauer, Ewald Srebotnik and Georg Gübitz Biocatalyzed approach for the surface functionalization of poly(L-lactic acid) films using hydrolytic enzymes Biotechnology Journal 10, 1739-1749, 2015 Show publication in PURE
Peter Hofer, Andras Boeszoermenyi, Doris Jaeger, Ursula Feiler, Haribabu Arthanari, Nicole Mayer, Fabian Zehender, Gerald Rechberger, Monika Oberer, Robert Zimmermann, Achim Lass, Guenter Haemmerle, Rolf Breinbauer, Rudolf Zechner and Karina Preiss-Landl Fatty acid-binding proteins interact with comparative gene identification-58 linking lipolysis with lipid ligand shuttling The Journal of Biological Chemistry 290, 18438-18453, 2015 Show publication in PURE
Ulrike Taschler, Renate Schreiber, Chandramohan Chitraju, Gernot F. Grabner, Matthias Romauch, Heimo Wolinski, Guenter Haemmerle, Rolf Breinbauer, Rudolf Zechner, Achim Lass and Robert Zimmermann Adiose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of the hepatic stellate cells Biochimica et Biophysica Acta 1851, 937-945, 2015 Show publication in PURE
Nicole Mayer, Martina Schweiger, Michaela-Christina Melcher, Christian Fledelius, Rudolf Zechner, Robert Zimmermann and Rolf Breinbauer Structure-activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL) Bioorganic & Medicinal Chemistry 23, 2904-2916, 2015 Show publication in PURE
Jakov Ivkovic, Christian Lembacher-Fadum and Rolf Breinbauer A rapid and efficient one-pot method for the reduction of N-protected alpha-amino acids to chiral alpha-amino aldehydes using CDI/DIBAL-H Organic & biomolecular chemistry 13, 10456-10460, 2015 Show publication in PURE
Other Article
Eveline Brodl, Chaitanya Tabib, Jakov Ivkovic, Rolf Breinbauer and Peter Macheroux The mystery of myrFMN production by bioluminescent bacteria Show publication in PURE
Eveline Brodl, Chaitanya Tabib, Thomas Bergner, Jakov Ivkovic, Rolf Breinbauer and Peter Macheroux The role of luciferase in myrFMN formation Show publication in PURE
Marko Kljajic and Rolf Breinbauer A Base- and Additive-Free Approach of the Tsuji-Trost Reaction for the Synthesis of N-Heterocycles Show publication in PURE
Christian Lembacher-Fadum, Jakov Ivkovic, Shalinee Jha, Prashant Kumar, Karl Gruber, Peter Macheroux and Rolf Breinbauer Design and Synthesis of Inhibitors of Dipeptidyl Peptidase-III Show publication in PURE
Patrick Simon Dobrounig and Rolf Breinbauer Iterative Suzuki-Coupling for the Synthesis of an Amphiphilic Oligoaryl-based ApoA1 Mimetic as a Potential Drug Carrier Show publication in PURE
Shalinee Jha, Ulrike Taschler, Jakov Ivkovic, Rolf Breinbauer, Robert Zimmermann and Peter Macheroux Characterization and therapeutic potential of DPP III knockout mice Show publication in PURE
Wolf-Dieter Lienhart, Emilia Sofia Strandback, Klaus Zangger, Rolf Breinbauer, Karl Gruber and Peter Macheroux NAD( P)H:quinone oxidoreductase 1 as a crucial enzyme in human cancer development and treatment Show publication in PURE
Christian Lembacher-Fadum, Jakov Ivkovic, Shalinee Jha, Prashant Kumar, Karl Gruber, Peter Macheroux and Rolf Breinbauer Design and Synthesis of Inhibitors of Dipeptidyl Peptidase-III Show publication in PURE
Jakob Pletz, Matthias Mentel, Christina Diederich, Wulf Blankenfeldt and Rolf Breinbauer Synthesis of chemical probes to investigate the Mechanism of PhzA/B Show publication in PURE
Jakov Ivkovic, Prashant Kumar, Silvia Wallner, Peter Macheroux, Karl Gruber and Rolf Breinbauer Structure-Based Design and Synthesis of Inhibitors of Dipeptidylpeptidase III (DPP3) Show publication in PURE
Eveline Brodl, Chaitanya Tabib, Jakov Ivkovic, Rolf Breinbauer and Peter Macheroux The mystery of myrFMN production by bioluminescent bacteria Show publication in PURE
Wolf-Dieter Lienhart, Emilia Sofia Strandback, Venugopal Gudipati, Michael Karl Uhl, Alexandra Binter, Klaus Zangger, Rolf Breinbauer, Karl Gruber and Peter Macheroux NAD(P)H:quinone oxidoreductase 1 as a crucial enzyme in human cancer development and treatment Show publication in PURE
Nicole Mayer, Martina Schweiger, Matthias Romauch, Jakov Ivkovic, Elisabeth Fuchs, Carina Julia Doler, Achim Lass, Gerhard Höfler, Rudolf Zechner, Robert Zimmermann and Rolf Breinbauer Discovery and Characterization of Atglistatin – The First Inhibitor of ATGL (Adipose Triglyzeride Lipase) Show publication in PURE
Jakob Pletz, Matthias Mentel, Christina Diederich, Wulf Blankenfeldt and Rolf Breinbauer Synthesis of chemical probes to investigate the Mechanism of PhzA/B Show publication in PURE
Chaitanya Tabib, Eveline Brodl, Thomas Bergner, Jakov Ivkovic, Silvia Wallner, Rolf Breinbauer and Peter Macheroux A luciferous surprise: A new natural aldehyde substrate for bacterial bioluminescence Show publication in PURE
Wolf-Dieter Lienhart, Emilia Sofia Strandback, Venugopal Gudipati, Michael Karl Uhl, Alexandra Binter, Klaus Zangger, Rolf Breinbauer, Karl Gruber and Peter Macheroux NAD(P)H:quinone oxidoreductase 1 as a crucial enzyme in human cancer development and treatment Show publication in PURE
Melanie Trobe, Martin Peters, Sebastian Grimm, Bernhard Wölfl and Rolf Breinbauer A modular synthesis of teraryl-based alpha-helix mimetics for inhibition of protein-protein-interactions Show publication in PURE
Kateryna Lypetska (Fesko), Gernot Strohmeier and Rolf Breinbauer Threonine Aldolases as Catalysts for the Synthesis of a-Quaternary a-Amino Acids Show publication in PURE
Melanie Trobe, Martin Peters, Sebastian Grimm, Bernhard Wölfl and Rolf Breinbauer A modular synthesis of teraryl-based α-helix mimetics for inhibition of protein-protein interactions Show publication in PURE
Nikolaus Guttenberger, Rolf Breinbauer and Wulf Blankenfeldt Development of Inhibitors of PhzE - A New Target for Antibiotic Intervention Show publication in PURE
Jakov Ivkovic, Prashant Kumar, Karl Gruber, Peter Macheroux and Rolf Breinbauer Design and Synthesis of Inhibitors of DPP3 Show publication in PURE
2014
Book Chapter
Jana Rentner, Rolf Breinbauer and Mandana Gruber Enzymes in Organic SynthesisKirk-Othmer Encyclopedia1-43 Show publication in PURE
Journal Article
Jana Rentner, Marko Kljajic, Lisa Offner and Rolf Breinbauer Recent advances and applications of reductive desulfurization in organic synthesis Tetrahedron 70, 8983-9027, 2014 Show publication in PURE
Georg Schneditz, Jana Rentner, Sandro Roier, Jakob Pletz, Kathrin A. T. Herzog, Roland Brücker, Hanno Tröger, Stefan Schild, Hansjörg Weber, Rolf Breinbauer, Gregor Gorkiewicz, Christoph Högenauer and Ellen L. Zechner Enterotoxicity of a nonribosomal peptide causes antibiotic-associated colitis Proceedings of the National Academy of Sciences of the United States of America 111, 13181-13186, 2014 Show publication in PURE
Melanie Trobe, Martin Peters, Sebastian H. Grimm and Rolf Breinbauer The Development of a Modular Synthesis of Teraryl-based alpha-Helix Mimetics as Potential Inhibitors of Protein-Protein Interactions Synlett 25, 1202-1214, 2014 Show publication in PURE
Christina Diederich, Mario Leypold, Rolf Breinbauer and Wulf Blankenfeldt Biosynthese der Phenazine Nachrichten aus der Chemie 62, 975-980, 2014 Show publication in PURE
Kateryna Lypetska, Gernot Strohmeier and Rolf Breinbauer Exploring the new threonine aldolases with broad donor specificity New Biotechnology 31, S87-S87, 2014 Show publication in PURE
Michael Toesch, Markus Schober, Rolf Breinbauer and Kurt Faber Stereochemistry and Mechanism of Enzymatic and Non-Enzymatic Hydrolysis of Benzylic sec-Sulfate Esters European Journal of Organic Chemistry , 3930-3934, 2014 Show publication in PURE
Rolf Breinbauer Festphasensynthese (Trendberichte Organische Chemie 2013) Nachrichten aus der Chemie 62, 273-274, 2014 Show publication in PURE
Sarah M. Pratter, Jakov Ivkovic, Ruth Birner-Gruenberger, Rolf Breinbauer, Klaus Zangger and Grit Daniela Straganz More than just a halogenase: modification of fatty acyl moieties by a trifunctional metal enzyme ChemBioChem 15, 567-574, 2014 Show publication in PURE
Alexander Gutmann, Linda Bungaruang, Hansjörg Weber, Mario Leypold, Rolf Breinbauer and Bernd Nidetzky Towards the synthesis of glycosylated dihydrochalcone natural products using glycosyltransferase-catalysed cascade reactions Green Chemistry 16, 4417-4425, 2014 Show publication in PURE
Other Article
Xuepu Yu, Elisabeth Fuchs and Rolf Breinbauer Diversity-Oriented Synthesis of a 2H-Imidazolidine Library Show publication in PURE
Kateryna Lypetska (Fesko) and Rolf Breinbauer Exploring the new Threonine Aldolases with broad donor specificity Show publication in PURE
Jakob Pletz, Matthias Mentel, Christina Diederich, Wulf Blankenfeldt and Rolf Breinbauer Synthesis of chemical probes to investigate the mechanism of PhzA/B Show publication in PURE
Melanie Trobe, Martin Peters, Sebastian Grimm, Bernhard Wölfl and Rolf Breinbauer A Modular Approach for the Synthesis of Teraryls – a-Helix Mimetics for the Inhibition of Protein-Protein-Interactions Show publication in PURE
Jakob Pletz, Matthias Mentel, Christina Diederich, Wulf Blankenfeldt and Rolf Breinbauer Synthesis of chemical probes to investigate the mechanism of PhzA/B Show publication in PURE
Mario Leypold, Hilmar Schroeder, Gernot Strohmeier, Timo Nuijens, Peter J. L. M. Quaedflieg and Rolf Breinbauer Racemization-Free Chemoenzymatic Peptide Synthesis Enabled via a Combination of Transition Metal and Enzyme Catalysis Show publication in PURE
Bernhard Wölfl, Melanie Trobe, Sebastian H. Grimm, Martin Peters and Rolf Breinbauer A Modular Synthesis of Teraryl-based α-Helix Mimetics for the Inhibition of Protein-Protein-Interactions Show publication in PURE
Patrick S. Dobrounig and Rolf Breinbauer A Modular Synthesis of an Amphiphilic Oligoaryl-based ApoA1 Mimetic as a Potential Drug Carrier Show publication in PURE
2013
Journal Article
N. Mayer, M. Schweiger, M. Romauch, G.F. Grabner, T.O. Eichmann, E. Fuchs, J. Ivkovic, C. Heier, I. Mrak, A. Lass, G. Höfler, C. Fledelius, Rudolf Zechner, Robert Zimmermann and R. Breinbauer Development of small-molecule inhibitors targeting adipose triglyceride lipase Nature Chemical Biology 9, 785-787, 2013 Show publication in PURE
Rolf Breinbauer Chemical Synthesis of Hormones, Pheromones and Other Bioregulators (by K. Mori) Synthesis 45, 978-978, 2013 Show publication in PURE
Georg Schneditz, Jana Rentner, Kathrin A. Herzog, Georg Gorkiewicz, Sandro Roier, Stefan Schild, Rolf Breinbauer, Ellen Zechner and Christoph Högenauer It takes two to tango: Klebsiella oxytoca overgrowth and production of Tilivalline, a cytotoxin, are the key events causing Antibiotic-Associated Hemorrhagic Colitis Zeitschrift für Gastroenterologie 51, A50-A50, 2013 Show publication in PURE
Martin Peters, Melanie Trobe and Rolf Breinbauer A Modular Synthesis of Teraryl-Based α-Helix Mimetics, Part 2: Synthesis of 5-Pyridine Boronic Acid Pinacol Ester Building Blocks with Amino Acid Side Chains in 3-Position Chemistry - a European Journal 19, 2450-2456, 2013 Show publication in PURE
Martin Peters, Melanie Trobe, Hao Tan, Rolf Kleineweischede and Rolf Breinbauer A Modular Synthesis of Teraryl based alpha-Helix Mimetics, Part 1: Synthesis of Core Fragments with two Electronically Differentiated Leaving Groups Chemistry - a European Journal 19, 2442-2449, 2013 Show publication in PURE
Rolf Breinbauer Festphasensynthese (Trendberichte Organische Chemie 2012) Nachrichten aus der Chemie 61, 280-281, 2013 Show publication in PURE
Srinivasan Rengachari, Philipp Aschauer, Matthias Schittmayer, Nicole Mayer, Karl Gruber, Rolf Breinbauer, Ruth Birner-Gruenberger, Ingrid Dreveny and Monika Oberer Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase The Journal of Biological Chemistry 288, 31093-31104, 2013 Show publication in PURE
Kateryna Fesko, Kerstin Steiner, Rolf Breinbauer, Helmut Schwab, Martin Schürmann and Gernot Strohmeier Investigation of one-enzyme systems in the w-transaminase-catalyzed synthesis of chiral amines Journal of Molecular Catalysis B 96, 103-110, 2013 Show publication in PURE
Hilmar Schröder, Gernot A. Strohmeier, Mario Leypold, Timo Nuijens, Peter J. L. M. Quaedflieg and Rolf Breinbauer Racemization-Free Chemoenzymatic Peptide Synthesis Enabled by the Ruthenium-Catalyzed Synthesis of Peptide Enol Esters via Alkyne-Addition and Subsequent Conversion Using Alcalase-Cross-Linked Enzyme Aggregates Advanced Synthesis & Catalysis 355, 1799-1807, 2013 Show publication in PURE
Elisabeth Brehm and Rolf Breinbauer Investigation of the origin and synthetic application of the pseudodilution effect for Pd-catalyzed macrocyclisations in concentrated solutions with immobilized catalysts Organic & biomolecular chemistry 11, 4750-4756, 2013 Show publication in PURE
Nicole Mayer, Martina Schweiger, Matthias Romauch, Gernot F. Grabner, Thomas F. Eichmann, Elisabeth Fuchs, Jakov Ivkovic, Christoph Heier, Irina Mrak, Achim Lass, Gerald Höfler, Christian Fledelius, Rudolf Zechner, Robert Zimmermann and Rolf Breinbauer Development of small molecule inhibitors for adipose triglyceride lipase Nature Chemical Biology 9, 785-787, 2013 Show publication in PURE
Kateryna Lypetska (Fesko), Kerstin Steiner, Rolf Breinbauer, Helmut Schwab, Martin Schuermann and Gernot Strohmeier Investigation of one-​enzyme systems in the ω-​transaminase-​catalyzed synthesis of chiral amines Journal of Molecular Catalysis B 96, 103-110, 2013 Show publication in PURE
Other Article
Melanie Trobe, Martin Peters, Sebastian Grimm and Rolf Breinbauer A Modular Synthesis of Teraryl-based α-Helix Mimetics for the Inhibition of Protein-Protein-Interactions Show publication in PURE
Nicole Mayer, Martina Schweiger, Matthias Romauch, Jakov Ivkovic, Elisabeth Fuchs, Achim Lass, Gerald Höfler, Rudolf Zechner, Robert Zimmermann and Rolf Breinbauer Discovery and Characterization of Atglistatin – The First Inhibitor of ATGL (Adipose Triglyzeride Lipase) Show publication in PURE
Hilmar Schröder, Gernot Strohmeier, Mario Leypold, Timo Nuijens, Peter J. L. M. Quaedflieg and Rolf Breinbauer Racemization-Free Chemoenzymatic Peptide Synthesis via a Combination of Transition Metal and Enzyme Catalysis Show publication in PURE
Nikolaus Guttenberger, Rolf Breinbauer and Wulf Blankenfeldt Development of Inhibitors of PhzE- A New Target for Antibiotic Intervention Show publication in PURE
Melanie Trobe, Martin Peters, Sebastian Grimm and Rolf Breinbauer A Modular Synthesis of Teraryl-based α-Helix Mimetics for the Inhibition of Protein-Protein-Interactions Show publication in PURE
Jakov Ivkovic, Prashant Kumar, Karl Gruber, Peter Macheroux and Rolf Breinbauer Design and synthesis of inhibitors of dipeptidyl peptidase-III Show publication in PURE
Jakob Pletz, Matthias Mentel, Christina Diederich, Wulf Blankenfeldt and Rolf Breinbauer Synthesis of chemical probes to investigate the mechanism of PhzA/B Show publication in PURE
Marko Kljajic and Rolf Breinbauer Investigation of the palladium catalyzed C-allylation of phenols Show publication in PURE
Kateryna Lypetska (Fesko), Herfried Griengl and Rolf Breinbauer Biocatalytic access to a,a-dialkyl-a-amino acids Show publication in PURE
Melanie Trobe, Hilmar Schröder and Rolf Breinbauer Pd-Catalyzed Allylation – a Powerful Tool for Post-Translational Modification of Proteins Show publication in PURE
Xuepu Yu, Elisabeth Fuchs and Rolf Breinbauer Diversity-Oriented Synthesis of a 2H-Imidazolidine Library Show publication in PURE
Mario Leypold and Rolf Breinbauer Phenazine Biosynthesis - Novel Enzyme Mechanism in Nature? Show publication in PURE
Jakov Ivkovic, Gustavo Arruda Bezerra, Karl Gruber and Rolf Breinbauer Design and synthesis of inhibitors of dipeptidyl peptidase-III Show publication in PURE
Martina Geier, Manuela Killinger, Birgit Wiltschi, Mandana Gruber-Khadjawi, Kateryna Lypetska, Gernot Strohmeier, Rolf Breinbauer, Nikolaus Turrini, Kurt Faber and Anton Glieder ACIB and CHEM21: Towards greener and more sustainable pharmaceutical manufacturing processes Show publication in PURE
2012
Book Chapter
Joanna Krysiak and Rolf Breinbauer Activity-Based Protein Profiling for Natural Product Target DiscoveryTopics Current Chemistry43-84 Show publication in PURE
Journal Article
Jana Rentner and Rolf Breinbauer An efficient labelling strategy of drug like molecules with functionalized alkyl linkers using CH-activation Chemical Communications 48, 10343-10345, 2012 Show publication in PURE
Rolf Breinbauer Festphasensynthese (Trendberichte Organische Chemie 2011) Nachrichten aus der Chemie 60, 286-286, 2012 Show publication in PURE
Joanna M. Krysiak, Johannes Kreuzer, Peter Macheroux, Albin Hermetter, Stephan A. Sieber and Rolf Breinbauer Activity-Based Probes for Studying the Activity of Flavin-Dependent Oxidases and for the Protein Target Profiling of Monoamine Oxidase Inhibitors Angewandte Chemie - International Edition 51, 7035-7040, 2012 Show publication in PURE
Joanna Maria Krysiak, Johannes Kreuzer, Peter Macheroux, Albin Hermetter, Stephan A. Sieber and Rolf Breinbauer Aktivitätsbasierte Sondenmoleküle zur Untersuchung der Aktivität Flavin-abhängiger Oxidasen und zum Zielprotein-Profiling von Monoaminooxidase-Inhibitoren Angewandte Chemie 124, 7142-7147, 2012 Show publication in PURE
Other Article
Joanna Maria Krysiak, Johannes Kreuzer, Stephan A. Sieber and Rolf Breinbauer Novel activity-based probes for studying the activity of flavin-dependent oxidases and for the protein target profiling of MAO-inhibitors Show publication in PURE
Joanna Maria Krysiak, Johannes Kreuzer, Stephan A. Sieber and Rolf Breinbauer Novel activity-based probes for studying the activity of flavin-dependent oxidases and for the protein target profiling of MAO-inhibitors Show publication in PURE
Melanie Trobe, Martin Peters and Rolf Breinbauer A Modular Approach for the Synthesis of Teraryls: a-Helix Mimetics for the Inhibition of Protein-Protein-Interaction Show publication in PURE
J. M. Krysiak, J. M. Kreuzer, S. A. Sieber and Rolf Breinbauer Novel activity-based probes for studying the activity of flavin-dependent oxidases and for the protein target profiling of MAO-inhibitors Show publication in PURE
2011
Journal Article
Rolf Breinbauer Festphasensynthese (Trendberichte Organische Chemie 2010) Nachrichten aus der Chemie 59, 275-275, 2011 Show publication in PURE
Matthias Mentel, Martin Peters, Jörg Albering and Rolf Breinbauer The Witkop–Winterfeldt oxidation converts tetrahydropyridoindoles into pyrroloquinolones and cinnolines by an unprecedented scaffold rearrangement Tetrahedron 67, 965-970, 2011 Show publication in PURE
Other Article
Jana Rentner and Rolf Breinbauer Innovative Synthetic Approaches for Covalent Drug Immobilization Show publication in PURE
Jana Rentner and Rolf Breinbauer Synthetic stategies for the covalent immobilization of drug molecules Show publication in PURE
Joanna Maria Krysiak and Rolf Breinbauer Novel pargyline-derived probes as effective proteomic tools for the active-site labelling of flavin-dependent oxidases Show publication in PURE
Martin Peters, Melanie Trobe and Rolf Breinbauer A Modular Approach for the Synthesis of Teraryl alpha-Helix Mimetics Show publication in PURE
2010
Book Chapter
Rolf Breinbauer Combinatorial Chemistry and the Synthesis of Compound LibrariesLigand-Macromolecular Interactions in Drug Discovery: Methods and Protocols, Methods in Molecular Biology, Vol. 57273-80 Show publication in PURE
Journal Article
Dirk Weinrich, Maja Köhn, Pascal Jonkheijm, Ulrika Westerlind, Leif Dehmelt, Hans Engelkamp, Peter C. M. Christianen, Jürgen Kuhlmann, Jan C. Maan, Dirk Nüsse, Hendrik Schröder, Ron Wacker, Edgar Voges, Rolf Breinbauer, Horst Kunz, Christof M. Niemeyer and Herbert Waldmann Preparation of Biomolecule Microstructures and Microarrays by Thiol-ene Photoimmobilization ChemBioChem 11, 235-247, 2010 Show publication in PURE
Rolf Breinbauer Festphasensynthese (Trendberichte Organische Chemie 2009) Nachrichten aus der Chemie 58, 282-282, 2010 Show publication in PURE
Martin Peters and Rolf Breinbauer A simple synthesis of functionalized 3-methyl-1-pyridinyl-1H-imidazolium salts as bidentate N-heterocyclic-carbene precursors and their application in Ir-catalyzed arene borylation Tetrahedron letters 51, 6622-6625, 2010 Show publication in PURE
Other Article
Rolf Breinbauer and Christian Slugovc Metalle verknüpfen Kohlenstoff - Chemienobelpreis 2010 Show publication in PURE
Joanna Maria Krysiak and Rolf Breinbauer Towards an extension of chemical biology toolbox – design and synthesis of novel activity-based probes targeting flavin-dependent oxidases Show publication in PURE
Joanna Maria Krysiak and Rolf Breinbauer Novel pargyline-derived probes as effective proteomic tools for the active-site labeling of monoamine oxidases Show publication in PURE
2009
Book Chapter
Rolf Breinbauer and Matthias Mentel The Use of Photoaffinity Labeling for the Identification of the Binding Site of the Antibiotic LinezolidChemical Biology – Learning through Case Studies79-88 Show publication in PURE
Rolf Breinbauer and M. Mentel The Introduction of Chemical Reporter Groups by Bioorthogonal Ligation Reactions for the Imaging of Cell-Surface GlycansChemical Biology – Learning through Case Studies221-232 Show publication in PURE
Rolf Breinbauer Solid-Phase Synthesis of BiomoleculesPost-translational modifications to regulate protein function to Xenobiotic metabolism354-361 Show publication in PURE
Journal Article
Matthias Mentel, Axel M. Schmidt, Michael Gorray, Peter Eilbarcht and Rolf Breinbauer Polystyrene Sulfonyl Chloride: A Highly Orthogonal Linker Resin for the Synthesis of Nitrogen-Containing Heterocycles Angewandte Chemie - International Edition 48, 5841-5844, 2009 Show publication in PURE
Matthias Mentel, Matthias J. Beier and Rolf Breinbauer An Environmentally Benign Electrochemical Process for the Reduction of Carboxylic Acid Hydrazides to Amides Synthesis , 1463-1468, 2009 Show publication in PURE
Rolf Breinbauer The Power of Functional Resins (Eds.J. Tulla-Puche, F. Albericio) Angewandte Chemie - International Edition 48, 3560-3561, 2009 Show publication in PURE
Rolf Breinbauer Classics in Stereoselective Synthesis (By E. M. Carreira, L. Kvaerno) Synthesis , 1760-1760, 2009 Show publication in PURE
Matthias Mentel, Wulf Blankenfeldt and Rolf Breinbauer The Active Site of an Enzyme Can Host Both Enantiomers of a Racemic Ligand Simultaneously Angewandte Chemie - International Edition 48, 9084-9087, 2009 Show publication in PURE
Rolf Breinbauer Festphasensynthese (Trendberichte Organische Chemie 2008) Nachrichten aus der Chemie 57, 266-266, 2009 Show publication in PURE
Matthias Mentel, Ekta G. Ahuja, Dmitri V. Mavrodi, Rolf Breinbauer, Linda S. Thomashow and Wulf Blankenfeldt Of Two Make One: The Biosynthesis of Phenazines ChemBioChem 10, 2295-2304, 2009 Show publication in PURE
Matthias Mentel, Wulf Blankenfeldt and Rolf Breinbauer Gleichzeitige Bindung beider Enantiomere eines racemischen Wirkstoffs durch das aktive Zentrum eines Enzyms Angewandte Chemie 121, 9248-9251, 2009 Show publication in PURE
Matthias Mentel, Axel M. Schmidt, Michael Gorray, Peter Eilbracht and Rolf Breinbauer Polystyrolsulfonylchlorid – ein hochorthogonales Linkerharz für die Synthese von Stickstoffheterocyclen Angewandte Chemie 121, 5955-5958, 2009 Show publication in PURE
2008
Book
Rolf Breinbauer Neuberufungen - Rolf Breinbauer978-3-902465-96-2 Show publication in PURE
Journal Article
Rolf Breinbauer The Way of Synthesis: Evolution of Design and Methods for Natural Products Synthesis , 330-330, 2008 Show publication in PURE
E. G. Ahuja, P. Janning, M. Mentel, A. Graebsch, Rolf Breinbauer, W. Hiller, B. Costisella, L. S. Tomashow, D. V. Mavrodi and W. Blankenfeldt PhzA/B Catalyzes the Formation of the Tricycle in Phenazine Biosynthesis Journal of the American Chemical Society 130, 17053-17061, 2008 Show publication in PURE
Rolf Breinbauer Festphasensynthese (Trendberichte Organische Chemie 2007) Nachrichten aus der Chemie 56, 286-287, 2008 Show publication in PURE
Pascal Jonkheijm, Dirk Weinrich, Maja Köhn, Hans Engelkamp, Peter C. M. Christianen, Jürgen Kuhlmann, Jan C. Maan, Dirk Nüsse, Hendrik Schroeder, Ron Wacker, Rolf Breinbauer, Christof M. Niemeyer and Herbert Waldmann Photochemical Surface Patterning by Thiol-Ene Reaction Angewandte Chemie - International Edition 120, 4493-4496, 2008 Show publication in PURE
Rolf Breinbauer The Synthetic Organic Chemist’s Companion (by M.C. Pirrung) Synthesis , 1486-1486, 2008 Show publication in PURE
Rolf Breinbauer Angewandte homogene Katalyse (by A. Behr) Synthesis , 3012-3012, 2008 Show publication in PURE
2007
Book Chapter
M Mentel and Rolf Breinbauer Combinatorial Solid Phase Natural Product ChemistryTopics Current Chemistry209-241 Show publication in PURE
Rolf Breinbauer, A Hillisch and H Waldmann Reverse Chemical Genetics – An Important Strategy for the Study of Protein Function in Chemical Biology and Drug DiscoveryChemical Biology355-384 Show publication in PURE
Journal Article
Rolf Breinbauer Domino Reactions in Organic Synthesis Synthesis , 794-794, 2007 Show publication in PURE
M Mentel and Rolf Breinbauer Electrons as a Reagent in Solid-Phase Organic Synthesis European Journal of Organic Chemistry , 4283-4292, 2007 Show publication in PURE
Rolf Breinbauer Festphasensynthesen (Trendbericht, Organische Chemie 2006) Nachrichten aus der Chemie 55, 266-267, 2007 Show publication in PURE
Rolf Breinbauer The Investigation of Organic Reactions and their Mechanisms Synthesis , 1438-1438, 2007 Show publication in PURE
M Köhn, M. Gutierrez-Rodriguez, P. Jonkheijm, S. Wetzel, R Wacker, Hendrik Schroeder, H Prinz, Christof M. Niemeyer, Rolf Breinbauer, S. E. Szedlacsek and Herbert Waldmann A Microarray Strategy for Mapping the Substrate Specificity of Protein Tyrosine Phosphatase Angewandte Chemie - International Edition 46, 7700-7703, 2007 Show publication in PURE
Rolf Breinbauer Organic Reactions in Water. Principles, Strategies, and Applications Synthesis , 3094-3094, 2007 Show publication in PURE
Rolf Breinbauer and M Mentel The Witkop-Winterfeldt-Oxidation of Indoles Current Organic Chemistry 11, 159-176, 2007 Show publication in PURE
Other Article
Rolf Breinbauer and Matthias Mentel Recent Research Highlights Show publication in PURE
2006
Journal Article
A Watzke, M Köhn, M Gutierrez-Rodriguez, R Wacker, H Schröder, Rolf Breinbauer, J Kuhlmann, K Alexandrov, C Niemeyer, R S Goody and H Waldmann Site Selective Protein Immobilization by Staudinger-Ligation Angewandte Chemie - International Edition 45, 1408-1412, 2006 Show publication in PURE
A Watzke, M Gutierrez-Rodriguez, M Köhn, R Wacker, Hendrik Schröder, Rolf Breinbauer, J Kuhlmann, K Alexandrov, C M Niemeyer, R S Goody and H Waldmann A generic building block for C- and N-terminal protein-labeling and protein immobilization Bioorganic & Medicinal Chemistry 14, 6288-6306, 2006 Show publication in PURE
S Nad, S Roller, R Haag and Rolf Breinbauer Electrolysis as an Efficient Key Step in the Homogeneous Polymer-Supported Synthesis of N-Substituted Pyrroles Organic letters 8, 403-406, 2006 Show publication in PURE
Rolf Breinbauer Festphasensynthesen (Trendbericht, Organische Chemie 2005) Nachrichten aus der Chemie 54, 245-245, 2006 Show publication in PURE
2005
Journal Article
S Nad and Rolf Breinbauer Electroorganic Synthesis of 2,5-Dialkoxydihydrofurans and Pyridazines on Solid Phase using Polymer Beads as Supports Synthesis , 3654-3665, 2005 Show publication in PURE
E Gonthier and Rolf Breinbauer Solid-supported Reagents and Catalysts for the Preparation of Large Ring Compounds Molecular diversity 9, 51-62, 2005 Show publication in PURE
2004
Book Chapter
Rolf Breinbauer, M Köhn and C Peters Small molecule arraysHighlights in Bioorganic Chemistry485-500 Show publication in PURE
Rolf Breinbauer and H Waldmann Introduction: Chemical Biology – A New Science at the Crossroads of Chemistry and BiologyChemical Biology - A Practical Course1-15 Show publication in PURE
Journal Article
M Köhn and Rolf Breinbauer The Staudinger Ligation - A Gift to Chemical Biology Angewandte Chemie - International Edition 43, 3106-3116, 2004 Show publication in PURE
S Nad and Rolf Breinbauer Electroorganic Synthesis on Solid Phase using Polymer Beads as Supports Angewandte Chemie - International Edition 43, 2297-2299, 2004 Show publication in PURE
M Westhus, E Gonthier, D Brohm and Rolf Breinbauer An efficient and inexpensive scavenger resin for Grubbs' catalyst Tetrahedron letters 45, 3141-3142, 2004 Show publication in PURE
2003
Book Chapter
Rolf Breinbauer, I R Vetter and H Waldmann From Protein Domains to Drug Candidates – Natural Products as Guiding Principles in Compound Library Design and SynthesisSmall Molecule – Protein Interactions (Ernst Schering Research Foundation, Workshop 42167-188 Show publication in PURE
Journal Article
Rolf Breinbauer Chemical Genetics Goes (Zebra) Fishing Angewandte Chemie - International Edition 42, 1116-1118, 2003 Show publication in PURE
E Gonthier and Rolf Breinbauer An easily accessible resin-supported palladium catalyst for Sonogashira coupling Synlett , 1049-1051, 2003 Show publication in PURE
Rolf Breinbauer and M Köhn Azide-alkyne Coupling - A Powerful Reaction for Bioconjugate Chemistry ChemBioChem 4, 1147-1149, 2003 Show publication in PURE
M Köhn, R Wacker, C Peters, H Schröder, L Soulere, Rolf Breinbauer, C M Niemeyer and H Waldmann Staudinger-Ligation: A new Immobilization Strategy for the Preparation of Small Molecule Arrays Angewandte Chemie - International Edition 42, 5830-5834, 2003 Show publication in PURE
M A Koch, Rolf Breinbauer and H Waldmann Protein Structure Similarity as Guiding Principle for Combinatorial Library Design Biological Chemistry 384, 1265-1272, 2003 Show publication in PURE
2002
Book Chapter
Rolf Breinbauer, S Sommer and H Waldmann Polymer-supported synthesis of non-oligomeric natural productsOrganic Synthesis Highlights V395-408 Show publication in PURE
Journal Article
Rolf Breinbauer, M Manger, M Scheck and H Waldmann Natural Product Guided Compound Library Development Current Medicinal Chemistry 9, 2129-2145, 2002 Show publication in PURE
Rolf Breinbauer, I R Vetter and H Waldmann From protein domains to drug candidates – natural products as guiding principles in Angewandte Chemie - International Edition 41, 2878-2890, 2002 Show publication in PURE
2001
Journal Article
M T Reetz, M Winter, Rolf Breinbauer, T Thurn-Albrecht and W Vogel Size-selective electrochemical preparation of surfactant-stabilized Pd- Ni- and Pt/Pd Chemistry - a European Journal 7, 1084-1094, 2001 Show publication in PURE
2000
Journal Article
E N Jacobsen and Rolf Breinbauer Nickel comes full cycle Science 287, 437-438, 2000 Show publication in PURE
Rolf Breinbauer and E N Jacobsen Cooperative asymmetric catalysis with dendrimer bound [Co(salen)] catalysts Angewandte Chemie - International Edition 39, 3604-3607, 2000 Show publication in PURE
1998
Journal Article
M T Reetz, Rolf Breinbauer, P Wedemann and P Binger Nanostructured nickel-clusters as catalysts in [3+2]-cycloaddition reactions Tetrahedron 54, 1233-1240, 1998 Show publication in PURE
1996
Journal Article
M T Reetz, Rolf Breinbauer and K Wanninger Suzuki and Heck reactions catalyzed by preformed palladium clusters and palladium/ Tetrahedron letters 37, 4499-4502, 1996 Show publication in PURE
1995
Journal Article
M T Reetz, S A Quaiser, Rolf Breinbauer and B Tesche A new strategy in heterogenous catalysis: the design of cortex-catalysts Angewandte Chemie - International Edition 34, 2728-2730, 1995 Show publication in PURE