2018
Engineered bidirectional promoters enable rapid multi-gene co-expression optimization
Nature Communications
9,
3589,
2018
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Production of Hydroxynitrile Lyase from Davallia tyermannii (DtHNL) in Komagataella phaffii and Its Immobilization as a CLEA to Generate a Robust Biocatalyst
ChemBioChem
19,
312-316,
2018
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Bio-based α,ω functionalized hydrocarbons from multi-step reaction sequences with bio- and metallo-catalysts based on the fatty acid decarboxylase OleTJE
ChemCatChem
10,
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2018
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Construction of a cellulose-metabolizing Komagataella phaffii (Pichia pastoris) by co-expressing glucanases and β-glucosidase
Applied Microbiology and Biotechnology
102,
1297-1306,
2018
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Localization of Cholesterol within Supported Lipid Bilayers Made of a Natural Extract of Tailor-Deuterated Phosphatidylcholine
Langmuir
34,
472-479,
2018
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Recombinant expression, purification and biochemical characterization of kievitone hydratase from Nectria haematococca
PLoS ONE
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2018
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Perdeuteration of cholesterol for neutron scattering applicatioins using recombinant Pichia pastoris
Chemistry and Physics of Lipids
212,
80-87,
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Identification of key residues for enzymatic carboxylate reduction
Frontiers in Microbiology
9,
2018
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Modification of Membrane Lipid Compositions in single-celled organisms–from Basics to Applications
Methods
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50 - 65,
2018
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The Impact of Deuteration on Natural and Synthetic Lipids: a Neutron Diffraction Study
Colloids and Surfaces B: Biointerfaces
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Small molecule Aldehydes from Carboxylic acid bioreduction
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Library growth and protein expressionMethods in Molecular Biology145-156
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Biocatalytic oxidation reactions - a Chemist's perspective
Angewandte Chemie - International Edition
57,
9238-9261,
2018
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Enzymatic Decarboxylation as a Tool for the Enzymatic Defunctionalization of Hydrophobic Bio-based Organic AcidsLipid Modification by Enzymes and Engineered Microbes89-118
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On the current role of hydratases in biocatalysis
Applied Microbiology and Biotechnology
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5841-5858,
2018
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MICROBIAL INDUCED ACID CORROSION FROM A FIELD PERSPECTIVE – ADVANCES IN PROCESS UNDERSTANDING AND CONSTRUCTION MATERIAL DEVELOPMENTProceedings of final conference of RILEM TC 253-MCI3-10
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Whole-cell (+)-ambrein production in the yeast Pichia pastoris
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Screening for new plant hydroxynitrile lyases
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Fatty Alcohols: enzymatically from Free fatty Acids
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The ABAO assay, a new tool for Carboxylic Acid Reductase engineering
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Fragrance synthesis via a chemo- & multi enzyme cascade
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Whole-cell (+)-ambrein production in the yeast Pichia pastoris
Metabolic Engineering Communications
7,
2018
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A novel assay for the detection of carboxylic acid reductase (CAR) activity in whole cells
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Aliphatic hydroxylation and epoxidation of capsaicin by Cytochrome P450 CYP505X
Tetrahedron
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6199-6204,
2018
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Discovery and characterization of the tubercidin biosynthetic pathway from Streptomyces tubercidicus NBRC 13090
Microbial Cell Factories
17,
2018
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Alternative Binding Mode impairs Enantioselectivity of Arylmalonate Decarboxylase
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Hetero- and Autotrophically Driven Biotransformations in C.Necator
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Hybrid CARs (carboxylate reductases)
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The Extreme Structural Plasticity in the CYP153 Subfamily of P450s Directs Development of Designer Hydroxylases
Biochemistry
57,
6701-6714,
2018
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Phylogenomics uncovers early hybridization and adaptive loci shaping the radiation of Lake Tanganyika cichlid fishes
Nature Communications
9,
2018
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Combinatorial optimization strategies to increase Human P450 catalytic Activity in whole cell
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Substrate independent high-throughput assay for the quantitative assessment of carboxylic acid reductase activity in living cells
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Synthesis of fragrance aldehydes by the combination of chemo and biocatalysis in microbial cell factories
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Whole-cell (+)-ambrein production in the yeast Pichia pastoris
Metabolic Engineering Communications
7,
2018
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A light-driven enzyme cascade reaction for the synthesis of lactones
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A light-driven enzyme cascade reaction for the synthesis of lactones.
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Cloning and characterization of a new delta-specific L-leucine dioxygenase from Anabaena variabilis
Journal of Biotechnology
284,
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2018
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Raman Microspectroscopic Evidence for the Metabolism of a Tyrosine Kinase Inhibitor, Neratinib, in Cancer Cells
Angewandte Chemie - International Edition
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7250-7254,
2018
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Phosphorylation by the stress-activated MAPK Slt2 down-regulates the yeast TOR complex 2
Genes and Development
32,
1576-1590,
2018
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Parallelized biocatalytic scanning probe lithography for the additive fabrication of conjugated polymer structures
Nanoscale
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Practical considerations regarding the choice of the best high-throughput assayMethods in Molecular Biology189-208
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Cytochrome P450 CYP505 mutants for biooxidations of active pharmaceutical ingredients
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New “old yellow enzyme”: a reductive C-C bond formation using engineered enoate reductase
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Cytochrome P450 CYP505 mutants for biooxidations of active pharmaceutical ingredients
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Small molecule Aldehydes from Carboxylic acid bioreduction
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Identification of key residues in Neurospora crassa Carboxylate reductase (CAR)
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Enzymatic alkene cleavage to Aldehydes and ketones
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Photosynthesis-driven Asymmetric reduction of c=c double bonds
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A ‘COMBINATORIAL EXPLOSION’ OF PRODUCTS THROUGH PHOTO-CHEMO-ENZYMATIC CASCADES
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SETUP AND CHARACTERIZATION OF A CASCADE TRANSFORMING ARYL ALCOHOLS INTO Β-NITRO-ARYL ALCOHOLS
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Photobiocatalytic Nicotinamide Recycling
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Cascade reactions for aldehyde generation in vivo
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Catalytic Cascades – ‘En Route’ to Applied Biochemical Cell Factories
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Reconstruction of mitochondrial genotypes from diverse next generation sequencing datasetsProceedings of the 10th International joint conference on Biomedical Engineering Systems and Technologiesin press
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S620A Mutation in Neurospora crassa Carboxylic acid Reductase abolishes Function
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Plant Defense as a Biotech Tool
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How to prepare flavors and fragrances by enzymes
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Practical Considerions Regarding the Choice of High-Throughput-AssaysProtein Engineering- Methods and Protocols189-208
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Pichia pastoris Alcohol Oxidase 1 (AOX1) Core Promoter Engineering by High Resolution Systematic Mutagenesis
Biotechnology Journal
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2017
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Expanding the CRISPR/Cas9 toolkit for Pichia pastoris with efficient donor integration and alternative resistance markers
Journal of Cellular Biochemistry
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2017
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Cloning and upscale production of monoamine oxidase N (MAO-N D5) by Pichia pastoris
Biotechnology Letters
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2017
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Synthetic Core Promoters as Universal Parts for Fine-Tuning Expression in Different Yeast Species
ACS Synthetic Biology
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471-484,
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Application of hydratases for flavour and fragrance synthesis
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Application of hydratases for flavor and fragrance synthesis
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Enhancing cytochrome P450-mediated conversions in P. pastoris
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Enhancing (+)-nootkatone production in Pichia pastoris and Saccharomyces cerevisiae through cytochrome P450-mediated conversions
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Chemicals made by Pichia pastoris
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Heme Enzymes for Biocatalysis
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Protein expression: Yeast or E. coli
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Enhancing (+)-nootkatone production in P. pastoris and S. cerevisiae through CYP450-mediated conversions
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Crystal structure of a novel (R)-selective amine transaminase and approaches to broaden its substrate scope by rational engineering
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NR4A3 Suppresses Lymphomagenesis through Induction of Proapoptotic Genes
Cancer Research
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2375-2386,
2017
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Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis
Molecular Cancer
16,
2017
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Transcriptome Profiling of the Australian arid-land Plant Eremophila serrulata for the Identification of Monoterpene synthases
Phytochemistry
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15-22,
2017
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Evolving Enzymes for BiocatalysisConsequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids: Production of Fuels and Chemicals1-17
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Four distinct types of E.C. 1.2.1.30 enzymes can catalyze the reduction of carboxylic acids to aldehydes
Journal of Biotechnology
257,
222-232,
2017
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Crystal Structure and Catalytic Mechanism of CouO, a Versatile C-Methyltransferase from Streptomyces rishiriensis
PLoS ONE
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1-14,
2017
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In Vivo Synthesis of Polyhydroxylated Compounds from a “Hidden Reservoir” of Toxic Aldehyde Species
ChemCatChem
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2919-2923,
2017
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Circulating Nucleic Acids as Early Diagnostic Markers for Sepsis
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Structure-based reaction mechanism of oleate hydratase from Elizabethkingia meningoseptica
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Circulating Nucleic Acids as Early Diagnostic Markers
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Exploring the Substrate Scope of a Phenolic Acid Decarboxylase Variant
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Stabilization of a cancer associated variant of human NQO1 by the use of small-molecular chaperones
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Whole Cell Substrate Screening of Carboxylic acid Reductases
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Rescuing the stability and activity of a cancer associated variant of human NQO1 by small molecular chaperones
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Combinatorial optimization strategies to increase Human P450 catalytic Activity in whole cell Biotransformations
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Rescuing the stability and activity of a cancer associated variant of human NQO1 by small molecular chaperones
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Substrate funnelling complements flux optimization tools to maximize product titers of in vivo cascades
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Concurrent optimization strategies for high level protein production: Process, strain and expression engineering
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Substrate specificity of CYP505X from Aspergillus fumigatus
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Towards improve expression of Neurospora crassa CAR to create efficient whole cell catalysts for aldehyde preparation
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Identification of key residues in Neurospora crassa Carboxylate reductase (CAR)
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Carboxylic Acid Reductase mediated Biotransformations
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Phase Separated Bicomponent Biopolymer Thin Films - Enzymatic Patterning and Protein Interaction
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Enzymatic Patterning of Phase Separated Bicomponent Biopolymer Thin Films
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Exploring the Substrate Scope of a Phenolic Acid Decarboxylase Variant
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Overcoming the incompatibility challenge in chemo-enzymatic and multi-catalytic cascade reactions.
Chemistry - a European Journal
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2017
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Enzymatic Oxyfunctionalization Driven by Photosynthetic Water-Splitting in the Cyanobacterium Synechocystis sp. PCC 6803
Catalysts
7,
2017
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An alternative approach towards poly-epsilon-caprolactone through a chemoenzymatic synthesis: combined hydrogenation, bio-oxidations and polymerization without the isolation of intermediates
Green Chemistry
19,
2017
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Photobiocatalytic alcohol oxidation using LED light sources
Green Chemistry
19,
376-379 ,
2017
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Towards environmentally acceptable synthesis of chiral alpha-hydroxy ketones via oxidase-lyase cascades
Green Chemistry
19,
2017
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Process Development through Solvent Engineering in the Biocatalytic Synthesis of the Heterocyclic Bulk Chemical ε-Caprolactone
Journal of heterocyclic chemistry
54,
391-396,
2017
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2016
Selective preparation of Aldehydes using carboxylate reductases
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Towards API Metabolite Synthesis by Fungal Cytochrome P450 variants
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Chemo-, regio- and stereoselectivity of carboxylic acid reductases
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Biotechnological advances towards an enhanced peroxidase production in Pichia pastoris
Journal of Biotechnology
233,
181-9,
2016
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Combinatorial optimization of CRISPR/Cas9 expression enables precision genome engineering in the methylotrophic yeast Pichia pastoris
Journal of Biotechnology
235,
139-49,
2016
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Synergism of proteomics and mRNA sequencing for enzyme discovery
Journal of Biotechnology
235,
132-8,
2016
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Recombinant production of a peroxidase-protein G fusion protein in Pichia pastoris
Journal of Biotechnology
219,
24-27,
2016
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Production of aromatic plant terpenoids in recombinant baker´s yeastBiotechnology of Plant Secondary Metabolism79-89
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Lipid Data Analyzer: Automated Identification of Lipid Structures in High-Throughput LC-MS<sup>n</sup> Data
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Comprehensive (epi)genome characterisation of CHO cells in response to evolutionary pressures
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Integrative Analysis of OMICS Data
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Enzymes as Biodevelopers for Nano- And Micropatterned Bicomponent Biopolymer Thin Films.
Biomacromolecules
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2016
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Aberrant gene expression in human lung cancer cells after loss of ATGL
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Towards understanding the structural destabilization of a cancer associated variant of human NQO1
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Discovery and structural characterisation of new fold type IV-transaminases exemplify the diversity of this enzyme fold
Scientific Reports
6,
2016
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Structure of a Berberine Bridge Enzyme-Like Enzyme with an Active Site Specific to the Plant Family Brassicaceae
PLoS ONE
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2016
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Whole genome sequence-based serogrouping of Listeria monocytogenes isolates
Journal of Biotechnology
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2016
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Semiempirical QM/MM calculations reveal a step-wise proton transfer and an unusual thiolate pocket in the mechanism of the racemizing mutant G74C of arylmalonate decarboxylase
Catalysis Science & Technology
6,
4937-4944,
2016
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Oil sands tailings ponds harbour a small core prokaryotic microbiome and diverse accessory communities
Journal of Biotechnology
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2016
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An Esterase from Anaerobic Clostridium hathewayi Can Hydrolyze Aliphatic−Aromatic Polyesters
Environmental Science & Technology
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2016
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A new family of R-selective Hydroxynitrile lyases
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Aldehyde preparation with new fungal carboxylate reductases
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Convergent Carbon Flux via Substrate Funelling for the In Vivo Production of Reactive Aldehyde Species
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New “old yellow enzyme”: Reductive C-C bond formation using an engineered enoate reductase
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Light-driven whole cell biotransformation with recombinant cyanobacteria
Biospektrum
22,
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2016
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Special Issue on acib, Dedicated to the Occasion of Prof. Dr. Helmut Schwab's 65th Birthday
Journal of Biotechnology
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Carnivorous Nutrition in Pitcher Plants (Nepenthes spp.) via an Unusual Complement of Endogenous Enzymes
Journal of Proteome Research
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Optimization of Peptide Secretion in P. pastoris
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The family of berberine bridge enzyme-like proteins from <i>Arabidopsis thaliana</i>
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Sterol-modified P. pastoris: Membrane Protein Expression and Cell Physiology
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Berberine bridge enzyme-like proteins: a multi-gene family from vascular plants
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TRAMETES VERSICOLOR CARBOXYLATE REDUCTASE UNCOVERED
Monatshefte für Chemie - Chemical Monthly
147,
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2016
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Enhancing cytochrome P450-mediated conversions in P. pastoris
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CNA-based Markers for the detection of chronic diseases
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Structure-based reaction mechanism of oleate hydratase from Elizabethkingia meningoseptica
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Addressing proteolytic efficiency in enzymatic degradation therapy for celiac disease
Scientific Reports
6,
30980,
2016
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Metabolic engineering of Pichia pastoris for ginsenoside production
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Pichia pastoris mutants as host strains for efficient secretion of recombinant Branched Chain Aminotransferase (BCAT)
Journal of Biotechnology
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2016
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Sterol and terpenoid engineering in yeasts
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Berberine bridge enzyme-like proteins: From characterization to application
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Selective Enzymatic Transformation to Aldehydes in vivo by Fungal Carboxylate Reductase from Neurospora crassa
Advanced Synthesis & Catalysis
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Chemo-, regio- and stereoselectivity of carboxylic acid reductases
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Draft Genome Sequence of a 94-Year-Old Listeria monocytogenes Isolate, SLCC208
Genome Announcements
4,
2016
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Tuning the expression of Neurospora crassa carboxylic acid reductase towards an efficient whole cell catalyst for aldehyde preparation
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Characterization of two novel alcohol short-chain dehydrogenases/reductases from Ralstonia eutropha H16 capable of stereoselective conversion of bulky substrates
Journal of Biotechnology
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A new fungal carboxylic acid reductase for the preparation of aldehydes from acids
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Systems biocatalysis: para-alkenylation of unprotected phenols
Catalysis Science & Technology
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Enhancing cytochrome P450-mediated conversions in P. pastoris through RAD52 over-expression and optimizing the cultivation conditions
Fungal genetics and biology
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Expression of fungal cytochrome P450 variants in E. coli and their validation for API metabolite synthesis
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Identification and Characterization of 5 new (R)-selective w-Transaminases
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(R)-Selective Nitroaldol Reaction Catalyzed by Metal-Dependent Bacterial Hydroxynitrile Lyases
ChemCatChem
8,
2214-2216,
2016
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Concurrent optimization strategies for high level protein production: Protein, strain and expression engineering
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Access and use of fern hydroxynitrile lyase for biocatalysis
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Creating gene models for high-value enzymes from plants and fungi
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Oleate hydratase - structure function relationships and applicationPower of microbes in industry and environment33
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Oleate hydratases - structure function relationship and application
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Molecular profiling of phagocytic immune cells in Anopheles gambiae reveals integral roles for hemocytes in mosquito innate immunity
Molecular & Cellular Proteomics
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2016
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Inferring expressed genes by whole-genome sequencing of plasma DNA
Nature Genetics
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Curation of the genome annotation of Pichia pastoris (Komagataella phaffii) CBS7435 from gene level to protein function
FEMS Yeast Research
16,
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Human xanthine oxidase recombinant in E. coli: A whole cell catalyst for preparative drug metabolite synthesis
Journal of Biotechnology
235,
3-10,
2016
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Characterisation of Candida within the Mycobiome/Microbiome of the Lower Respiratory Tract of ICU Patients
PLoS ONE
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2016
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The flavodoxin-like proteins Pst2 and Ycp4 from Saccharomyces cerevisiae belong to the FMN-dependent NAD(P)H:quinone oxidoreductases
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Translin and Trax differentially regulate telomere-associated transcript homeostasis
OncoTarget
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33809-20,
2016
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Screening for improved isoprenoid biosynthesis in microorganisms
Journal of Biotechnology
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112–120,
2016
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Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time
Biotechnology and Bioengineering
113,
2241-53,
2016
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Dimension reduction techniques for the integrative analysis of multi-omics data
Briefings in Bioinformatics
17,
628-41,
2016
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A Toolbox of Diverse Promoters Related to Methanol Utilization
ACS Synthetic Biology
5,
172-86,
2016
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Scent of bitter almond and a pinch of –omics: discovering a novel hydroxynitrile lyase
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A Fed-Batch Synthetic Strategy for a Three-Step Enzymatic Synthesis of Poly-ϵ-caprolactone
ChemCatChem
8,
3446-3452,
2016
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Enzymatic Treatment for Patterning of Bicomponent Biopolymer Thin Films
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Comparison of SNP based and cgMLST based typing of Listeria monocytogenes isolates from Seeliger's historical "Special Culture Collection".
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Comparison of PFGE and NGS based typing of Listeria monocytogenes isolates
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Typing of Listeria monocytogenes - PFGE versus Whole Genome Sequencing
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Comparison of SNP based and cgMLST based typing of Listeria monocytogenes isolates from Seeliger's historical "Special Listeria Culture Collection"
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Selective preparation of Aldehydes using carboxylate reductases
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Biocatalytic Characterization of Human FMO5: Unearthing Baeyer-Villiger Reactions in Humans
ACS Chemical Biology
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2016
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A new family of R-selective Hydroxynitrile lyases
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The unique hydroxynitrile lyase from fern
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Improving the Properties of Bacterial R-selective Hydroxynitrile Lyases for Industrial Applications
ChemCatChem
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2015
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Complete switch from α-2,3- to α-2,6-regioselectivity in Pasteurella dagmatis β-D-galactoside sialyltransferase by active-site redesign
Chemical Communications
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3083-3086,
2015
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Bioprospecting for Hydroxynitrile Lyases by Blue Native PAGE Coupled HCN Detection
Current biotechnology
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Engineering Pichia pastoris for improved NADH regeneration
Beilstein Journal of Organic Chemistry
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1741-8,
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A toolbox of endogenous and heterologous nuclear localization sequences for the methylotrophic yeast Pichia pastoris
FEMS Yeast Research
15,
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Recombinant Expression of Trichoderma reesei Cel61A in Pichia pastoris
Molecular Biotechnology
57,
1010-7,
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Lipid Data Analyzer (LDA) 2: Flexible and Automatic Identification of Lipid Structures in High-Throughput LC-MSn Data from Various Instruments
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Non-homologous enzyme discovery: the hydroxynitrile lyases case
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Versatile plasmid-based expression systems for Gram-negative bacteria-General essentials exemplified with the bacterium Ralstonia eutropha H16.
New Biotechnology
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2015
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The regulatory network of yeast triacylglycerol lipases
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Roles of Thermophiles and Fungi in Bitumen Degradation in Mostly Cold Oil Sands Outcrops
Applied and Environmental Microbiology
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6825-6838 ,
2015
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Comparative analysis of metagenomes from three methanogenic hydrocarbon-degrading enrichment cultures with 41 environmental samples.
The ISME Journal
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7-Cyano-7-deazaguanine synthase: a reverse Nitrilase?
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Hydroxynitrile lyase from fern: A Unique Biocatalyst
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APPLYING CYTOCHROME P450 ENZYMES FOR FLAVOUR&FRAGRANCE BIOSYNTHESIS IN YEASTS
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Elucidation of the structure and mechanism of CouO, a small molecule C-Methyltransferase from streptomyces rishiriensis
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Fluoro amino acids: A rarity in nature, yet a prospect for protein engineering
Biotechnology Journal
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2015
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Complete switch from alpha2,3- to alpha2,6-regioselectivity in Pasteurella dagmatis beta-D-galactoside sialyltransferase by active-site redesign
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Oxidative Alkene Cleavage Catalysed by Manganese-Dependent Cupin TM1459 from Thermotoga maritima
Advanced Synthesis & Catalysis
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Complete switch from alpha2,3- to alpha2,6-regioselectivity in Pasteurella dagmatis beta-D-galactoside sialyltransferase by active-site redesign
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Over-expression of ICE2 stabilizes cytochrome P450 reductase levels in Saccharomyces cerevisiae and Pichia pastoris
Biotechnology Journal
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Transcriptome Profiling of Khat (Catha edulis) and Ephedra sinica Reveals Gene Candidates Potentially Involved in Amphetamine-Type Alkaloid Biosynthesis.
PLoS ONE
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Deriving patterns of gastrointestinal dysbiosis
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Design and Synthesis of Inhibitors of DPP3
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ON THE REACTION MECHANISM OF THE ELIZABETHKINGIA MENINGOSEPTICA OLEATE HYDRATASE
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The berberine bridge enzyme-like superfamily: A multi gene family involved in lignification, drought and pathogen response
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Expression of human sialyltransferase in yeast
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Optimizing cofactor availability for the production of recombinant heme peroxidase in Pichia pastoris.
Microbial Cell Factories
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Structure-based mechanism of oleate hydratase from Elizabethkingia meningoseptica
ChemBioChem
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Biochemical investigations on the human dimethylglycine dehydrogenase
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Identification and characterization of Tth-X and Pho-Y, novel members of the OYE family
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Expression of enantioselective enzymes in cyanobacteria
Microbial Cell Factories
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A New Class of Enzymes Discovered: A Non-Heme Oxidase Produces Medium-Chain 1-Alkenes
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Structural and biochemical characterization of a monolignol oxidoreductase from A. thaliana implies a link between the berberine bridge enzyme-like family and cell wall metabolism
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A combined bioinformatics and functional metagenomics approach to discovering lipolytic biocatalysts
Frontiers in Microbiology
6,
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Photobiocatalytic decarboxylation for olefin synthesis
Chemical Communications
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Rhizobiales as functional and endosymbiontic members in the lichen symbiosis of Lobaria pulmonaria L.
Frontiers in Microbiology
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Engineered hydrophobic pocket of (S)-selective arylmalonate decarboxylase variant by simultaneous saturation mutagenesis to improve catalytic performance
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α/β Hydrolase Domain-Containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate
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Biotransformations for drug metabolite synthesis
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Drug Metabolizing Enzymes: From Heterologous Expression to Drug Metabolite Synthesis
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Sphingolipids regulate telomere clustering by affecting transcriptional levels of genes involved in telomere homeostasis
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Enzyme catalyzed reduction of carboxylic acids
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Oxidation of monolignols by members of the berberine bridge enzyme family suggests a role in plant cell wall metabolism
The Journal of Biological Chemistry
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ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6
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Biot Number Effects on the Local Heat and Mass Transfer Rate in Fixed and Fluidized Beds
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Restriction site free cloning (RSFC) plasmid family for seamless, sequence independent cloning in Pichia pastoris
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1-15,
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Human FMO2-based microbial whole-cell catalysts for drug metabolite synthesis
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An updated view on horseradish peroxidases: recombinant production and biotechnological applications.
Applied Microbiology and Biotechnology
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Functioning of lichen symbioses is supported by a diversified bacterial microbiome
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Design and Synthesis of Inhibitors of Dipeptidyl Peptidase-III
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LincRNA-p21 acts as a mediator of ING1b-induced apoptosis
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The Nitrile forming Enzyme 7-Cyano-7-deazaguanine Synthase from Geobacillus kaustophilus: A reverse Nitrilase?
ChemBioChem
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Drug Metabolite Synthesis with Human Enzymes
International pharmaceutical industry
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Deciphering functional roles and beneficial contributions of the lichen-associated bacterial microbiome
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Compact multi-enzyme pathways in P. pastoris
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Decontaminator: detection and removal of contaminating sequences of unknown source
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Biotechnology of Cellular Membranes - Biosynthesis, Interactions and Functions of Hydrophobic Compounds
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Transcriptome analysis of 20 taxonomically related benzylisoquinoline alkaloid-producing plants.
BMC Plant Biology
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Eine Enzymkaskade zur Synthese von ε-Caprolacton und dessen Oligomeren
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Oxidative alkene cleavage activities among proteins with cupin fold
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Engineering of cupin hydroxynitrile lyases
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MiR-200a regulates epithelial to mesenchymal transition-related gene expression and determines prognosis in colorectal cancer patients
British Journal of Cancer
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MuteinDB: a database of enzyme variants linked to substrates, products, and enzymatic reaction properties using a standardized input format
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miR-26a and miR-26b as key regulators of human white and brite adipocyte differentiation
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Discovery of a novel (R)-selective bacterial cupin HNL from Acidobacterium capsulatum ATCC 51196 by a sequence-based approach
Computational and Structural Biotechnology Journal
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The potential of enzymes with cupin fold in biocatalysis
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Characterizing microbial and mammalian acyl-transferases in a cholesterol-producing yeast strain
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Engineered bacterial hydroxynitrile lyases, a promising new source of sustainable biocatalysts
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Pichia pastoris with improved NADH regeneration: A novel platform strain for whole-cell biocatalysis
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NR4A1-mediated apoptosis suppresses lymphomagenesis and is associated with a favorable cancer-specific survival in patients with aggressive B-cell lymphomas
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Novel enzymes for Biocatalysis
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Preliminary characterization of hFMO5. A human Bayer-Villiger Monooxygenase?
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NOVEL OXIDATIVE ACTIVITIES AMONG PROTEINS WITH CUPIN FOLD
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Human Xanthin Oxidase: Expression In E. coli and Drug Metabolite Synthesis
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MicroRNA-26 family is required for human adipogenesis and drives characteristics of brown adipocytes
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Synergistic modular promoter and gene optimization to push cellulase secretion by Pichia pastoris beyond existing benchmarks
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Generating a Platform of Human Non-CYP Drug Metabolizing Enzymes for API Modification
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Purification and basic biochemical characterization of 19 recombinant plant peroxidase isoenzymes produced in Pichia pastoris.
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Production of the sesquiterpenoid (+)-nootkatone by metabolic engineering of Pichia pastoris
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18-29,
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Hunting the needle in the haystack - A guide to obtain biologically meaningful microRNA targets
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Protein expression in Pichia pastoris: recent achievements and perspectives for heterologous protein production
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Generation of a neuro-specific microarray reveals novel differentially expressed noncoding RNAs in mouse models for neurodegenerative diseases
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High-quality production of human α-2,6-sialyltransferase in Pichia pastoris requires control over N-terminal truncations by host-inherent protease activities
Microbial Cell Factories
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2014
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Homologous and heterologous expression of dehydrogenases and oxidoreductases of Ralstonia eutropha H16
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Cofactor Specificity Engineering of Streptococcus mutans NADH Oxidase 2 for NAD (P)+ Regeneration in Biocatalytic Oxidations
Computational and Structural Biotechnology Journal
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Heterologous expression of membrane proteins in engineered yeasts - (+)-nootkatone production in yeasts
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A newly discovered multifunctional α2,3-sialyltransferase from Pasteurella dagmatis carries a natural Ser-to-Thr substitution
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New promoters and terminators for Pichia pastoris
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Human flavin monooxygenase 2: Heterologous expression in E. coli and API modification
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Longevity and sustainability of lichen symbioses are supported by a stable and versatile microbiome
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Analysis of microRNA transcription and post-transcriptional processing by Dicer in the context of CHO cell proliferation
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Unconventional Enzymatic Reductions: Nitriles and Carboxylates as Substrates
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Structural and biochemical characterization of two novel enzymes with promiscuous ene-reductase activity
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Thermostability improvement of endoglucanase Cel7B from Hypocrea pseudokoningii
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Mechanistic study of CMP-Neu5Ac hydrolysis by α2,3-sialyltransferase from Pasteurella dagmatis
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Versatile and stable vectors for efficient gene expression in Ralstonia eutropha H16
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Towards improved membrane protein production in Pichia pastoris: general and specific transcriptional response to membrane protein overexpression
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Extracellular transaminases for biocatalysis
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Production of macrocyclic sesqui‐and diterpenes in heterologous microbial hosts: A systems approach to harness Nature’s molecular diversity
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miR-26a and miR-26b as key regulators of human white and brite adipocyte differentiation
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(+)-Nootkatone production in yeasts
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Characterizing the Sterol Specificity of Microbial and Mammalian Acyltransferases
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Enzymatic decarboxylation—an emerging reaction for chemicals production from renewable resources
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(+)-Nootkatone production in yeasts
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Carbon source dependent promoters in yeasts
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Lipases as Sustainable Biocatalysts for the Sustainable Industrial Production of Fine Chemicals and Cosmetics
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PRODUCTION OF RECOMBINANT HUMAN ALDEHYDE OXIDASE IN E. COLI AND OPTIMIZATION OF ITS APPLICATION FOR PREPARATIVE SYNTHESIS OF OXIDIZED DRUG METABOLITES
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Methyltransferases in biocatalysisCascade Biocatalysis: Stereoselective and Environmentally Friendly Reactions
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Enzymatic Reductions of unconventioal substrates: Carboxylates and Nitriles
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Bioprospecting for new hydroxynitrile lyases using blue native PAGE coupled in-gel activity assay
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Identification of promiscuous ene-reductase activity by mining structural databases using active site constellations
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New tools for pathway generation employing the concepts of synthetic biology
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MicroRNA-26 family is required for human adipogenesis and drives brown adipocytes characteristics
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Pichia pastoris for efficient production of extracellular transaminases
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Microbial Lactone Synthesis Based on Renewable Resources
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Generation of a neuro-specific microarray reveals novel differentially expressed noncoding RNAs in mouse models for neurodegenerative diseases.
RNA
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Characterization of a multifunctional α2,3-sialyltransferase from Pasteurella dagmatis, carrying a natural Ser-to-Thr substitution
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Microbials for the production of monoclonal antibodies and antibody fragments
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Synthetic promoters enabling novel gene co-expression strategies
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Improved selectivity of an engineered multi-product terpene synthase
Organic & biomolecular chemistry
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Overexpression of membrane proteins from higher eukaryotes in yeasts
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Blue Native PAGE: bioprospecting for new hydroxynitrile lyases
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Purification and basic biochemical characterization of 19 recombinant plant peroxidase isoenzymes produced in Pichia pastoris
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Peroxidase gene discovery from the horseradish transcriptome
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MicroRNA-26 family is required for human adipogenesis and drives brown adipocyte characteristics
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Unconventional Enzymatic Reductions: Nitriles and Carboxylates as SubstratesNew BiotechnologyS1-S2
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Co-expressed genes prepositioned in spatial neighborhoods stochastically associate with SC35 speckles and RNA polymerase II factories
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Characterization of recombinant horseradish peroxidase isoenzymes from Pichia pastoris
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Human flavin monooxygenase 2: Heterologous expression in E. coli and API modificationNew BiotechnologyS82-S82
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MicroRNA functions in brite/brown fat - novel perspectives towards anti-obesity strategies
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Collapse of the native structure caused by a single amino acid exchange in human NAD(P)H:quinone oxidoreductase1
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MicroRNA functions in human fat cell development - Novel perspectives towards anti-obesity strategiesBIT´s Annual World Congress of Molecular & Cell Biology - 2014124-124
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Enantioselective trans-dihydroxylation of aryl olefins by cascade biocatalysis with recombinant escherichia coli coexpressing monooxygenase and epoxide hydrolase
ACS Catalysis
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Engineering of cupin hydroxynitrile lyases
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Characterization of recombinant horseradish peroxidase isoenzymes from Pichia pastoris
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Deciphering a functional network of symbiotic sustain with the microbiome of lichens by comparative omics
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Crystal structure of an (R)-selective ω-transaminase from Aspergillus terreus
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Synthetic Core Promoters for Pichia pastoris
ACS Synthetic Biology
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MiR-200a regulates epithelial to mesenchymal transition-related gene expression and determines prognosis in colorectal cancer patients
British Journal of Cancer
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2014
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Identification of microRNAs specific for high producer CHO cell lines using steady-state cultivation
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Novel mono- and bidirectional promoters in three different yeasts
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Discovery of fungal enzymes and pathwaysFungal Bio-Molecules: Sources, Applications and Recent Developments51-61
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Secretion of transaminase in Pichia pastoris
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Biocatalytic reduction of carboxylic acids
Biotechnology Journal
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Characterization of recombinant horseradish peroxidase isoenzymes from Pichia pastoris
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Structural studies on the hydroxynitrile lyase from Davallia tyermanii
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Crystal structure of an (R)-selective ω-transaminase from Aspergillus terreus (R)-selective ω-transaminase from Aspergillus terre
PLoS ONE
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Human Flavin Monooxygenases as a Tool for Drug Metabolite Synthesis
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Regulation of Pichia pastoris promoters and its consequences for protein production
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Carboxylate reductase - a novel route for 3-hydroxytyrosol production
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Enzymatic Nitrile Reduction
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Biochemical and structural characterization of a novel bacterial manganese-dependent hydroxynitrile lyase
The FEBS Journal
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Towards drug metabolite production on the multi-miligram scale: Generation of an efficient aldehyde oxidase (AOX1) based biocatalyst
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Increasing polyesterase activity towards synthetic polymers by diverse molecular approaches
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Fusion of binding-domains to Thermobifida cellulosilytica cutinase to tune sorption characteristics and enhancing PET hydrolysis
Biomacromolecules
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2013
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Cupins, a versatile family of metalloenzymes
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Double site saturation mutagenesis of the human cytochrome P450 2D6 results in regioselective steroid hydroxylation
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The role of surface amino acids on cutinases is a key to tune hydrolysis of polyethylene terephthalate
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Mannitol dehydrogenase as a tool for enzymatic oxidation of lipophilic substrates: alcohols and sugar alcohols
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A newly discovered multifunctional α2,3-sialyltransferase from Pasteurella dagmatis PdST carries a natural Ser-to-Thr substitution
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Knockout of an endogenous mannosyltransferase increases the homogeneity of glycoproteins produced in Pichia pastoris
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A new hydroxynitrile lyase from fern: from the plant to the sequence
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Functional expression of human Na,K-ATPase α3β1 isoform in a cholesterol producing Pichia pastoris strain
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The natural way to a natural product - microbial production of 3-hydroxytyrosol
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ACIB and CHEM21: Towards greener and more sustainable pharmaceutical manufacturing processes
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Homologous and heterologous expression of dehydrogenases and oxidoreductases of Ralstonia eutropha H16
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Discovery of new and improved hydroxynitrile lyases belonging to the cupin superfamily
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Integrative expression vectors for stable pathway construction in the yeast Schizosaccharomyces pombe
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Artificial Multi-Enzyme Networks for the Asymmetric Amination of sec-Alcohols
Chemistry - a European Journal
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4030-4035,
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Thermally driven asymmetric domino reaction catalyzed by a thermostable esterase and its variants
Tetrahedron Letters
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Sterol specificity of homologous and heterologous acyltransferases expressed in S. cerevisiae
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Functional expression of a human membrane transporter in a cholesterol-producing Pichia pastoris strain
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Enzymatic aerobic alkene cleavage catalyzed by a Mn3+-dependent proteinase A homologue
ChemBioChem
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A novel cholesterol-producing Pichia pastoris strain is an ideal host for functional expression of human Na,K-ATPase α3β1 isoform
Applied Microbiology and Biotechnology
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2013
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Bacterial transaminases for chiral amine synthesis - Expression and Secretion in Pichia pastoris
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De novo production of flavor compounds by engineered yeasts
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Characterization of a multifunctional alpha2,3-sialyltransferase from Pasteurella dagmatis, carrying a natural Ser-to-Thr substitution
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Cupins as scaffolds for novel activities
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Biocatalytic Thiol Alkylation
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Characterization of a multifunctional α2,3-sialyltransferase from Pasteurella dagmatis
Glycobiology
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Exploiting recombinant Pichia pastoris for drug metabolite synthesis: Towards an efficient CYP3A4-based whole-cell catalyst
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Secretion of transaminases in Pichia pastoris: a basic module for efficient synthesis of chiral amines
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A medium-throughput-screening method for the detection of the conversion of ketones by omega-transaminases
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New horseradish peroxidase isoenzymes and their production in Pichia pastoris
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Development of small-molecule inhibitors targeting adipose triglyceride lipase
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2013
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Metagenome analyses reveal the influence of the inoculant Lactobacillus buchneri CD034 on the microbial community involved in grass ensiling
Journal of Biotechnology
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Yarrowia lipolytica dehydrogenase/reductase: An enzyme tolerant for lipophilic compounds and carbohydrate substrates
Bioorganic & Medicinal Chemistry Letters
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Biocatalytic Thiol Alkylation
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Methyltransferase NovO - a Versatile Catalyst for Enzymatic Friedel-Crafts Alkylation
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Surface engineering of a cutinase from Thermobifida cellulosilytica for improved polyester hydrolysis
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Protein Engineering Using Eukaryotic Expression SystemsProtein Engineering Handbook - Volume 347-72
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Characterization of a multifunctional α2,3-sialyltransferase from Pasteurella dagmatis, carrying a natural Ser-to-Thr substitution
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Probing the secretory pathway of the yeast Pichia pastorisBook of abstracts38-38
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Targeting the Substrate Binding Site of E. coli Nitrile Reductase QueF by Modeling, Substrate and Enzyme Engineering
Chemistry - a European Journal
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Biocatalytic Thiol Alkylation
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RECENT DEVELOPMENTS IN HYDROXYNITRILE LYASES FOR INDUSTRIAL BIOTECHNOLOGY
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Recombinant hydroxynitrile lyase: high level expression in Pichia pastoris
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New opportunities by synthetic biology for biopharmaceutical production in Pichia pastoris
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Rec. ST6Gal-I variants to control enzymatic activity in processes of in vitro glycoengineering
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Investigation of one-enzyme systems in the w-transaminase-catalyzed synthesis of chiral amines
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A newly discovered multifunctional alpha2,3-sialyltransferase from Pasteurella dagmatis carries a natural Ser-to-Thr substitution
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Novel enone-reductases identified by database mining for catalytic promiscuity
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Functional expression of a human membrane transporter in a cholesterol-producing Pichia pastoris strains
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A newly discovered multifunctional α2,3-sialyltransferase from Pasteurella dagmatis PdST carries a natural Ser-to-Thr substitution
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First functional expression of cytochrome P450 3A4 in Pichia pastoris
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Pichia pastoris as whole-cell biocatalyst for (+)-nootkatone production
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Engineering of the yeast Pichia pastoris for high-level production of (+)-nootkatone
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Organaktivitäten im Schüttelkolben: Rekombinante menschliche Enzyme für die Pharmaindustrie
TU Graz Research
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Friedel-Crafts Alkylation catalyzed by Methyltransferases
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Insights into the completely annotated genome of Lactobacillus buchneri CD034, a strain isolated from stable grass silage
Journal of Biotechnology
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Friedel-Crafts Alkylation catalyzed by Methyltransferases
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NEW ENZYMATIC APPROACHES FOR POLYMER MODIFICATION
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Characterisation of bacterial hydroxynitrile lyases with a cupin fold
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(+)-Nootkatone production in yeasts
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Deletion of the Pichia pastoris KU70 homologue facilitates platform strain generation for gene expression and synthetic biology
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Expression of lignocellulolytic enzymes in Pichia pastoris
Microbial Cell Factories
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Sensitive high-throughput screening for the detection of reducing sugars
Biotechnology Journal
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Friedel-Crafts Alkylation catalyzed by Methyltransferases
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Alternative Cofactors for AdoMet-dependent Methyltransferases
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Enzymatic Nitrile Reduction
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Two-step enzymatic functionalisation of polyamide with phenolics
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High-Throughput Characterization of Fungal Communities
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Friedel-Crafts Alkylation catalyzed by Methyltransferases
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Recent advances in rational approaches for enzyme engineerings in rational approaches for enzyme engineering
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Investigations of the substrate scope of nitrile reductase queF
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Characterization of two bacterial hydroxynitrile lyases with high similarity to cupin superfamily proteins
Applied and Environmental Microbiology
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S. cerevisiae as Whole-Cell Biocatalyst for Terpenoid Production
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Yeast membrane engineering for improved protein expression
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The yeast Pichia pastors as whole cell biocatalyst for the production of terpenoid compounds
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Molecular Approaches to Increase Polyesterase Activity of Cutinase
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Molecular characterization of the C-Methyltransferase NovO of Streptomyces spheroides, a valuable enzyme for performing Friedel-Crafts alkylation
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Characterisation of bacterial hydroxynitrile lyases
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Expression of mammalian glycosyltransferases in yeast
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A novel multifunctional sialyltransferase PdST from Pasteurella dagmatis
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Organ Function in Shake Flasks: Recombinant Human Enzymes for the Pharmaceutical Industry
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Enzymatic functionalization of synthetic polymers via double enzymatic reaction
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Structure and mechanism of an inverting alkylsulfatase from Pseudomonas sp. DSM6611 specific for secondary alkyl sulfates
The FEBS Journal
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4374-4384,
2012
, DOI
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Recombinant protein expression in Pichia pastoris strains with an engineered methanol utilization pathway
Microbial Cell Factories
11,
22-35,
2012
, DOI
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Host cell and expression engineering for development of an E. coli ketoreductase catalyst: Enhancement of formate dehydrogenase activity for regeneration of NADH
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The short form of the recombinant CAL-A-type lipase UM03410 from the smut fungus Ustilago maydis exhibits an inherent trans-fatty acid selectivity
Applied Microbiology and Biotechnology
94,
141-50,
2012
, DOI
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Asymmetric decarboxylation of arylmalonates and racemization of profens by arylmalonate decarboxylase and its variants
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100% double site saturation by individual expression of 400 muteins in Pichia pastoris
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Characterization of a new cutinase from Thermobifida alba regarding PET-surface hydrolysis
Biocatalysis and Biotransformation
30,
2-9,
2012
, DOI
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MuteinDB: the mutein database linking substrates, products and enzymatic reactions directly with genetic variants of enzymes
Database - The Journal of Biological Databases and Curation
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bas028-bas028,
2012
, DOI
, Link
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A robust multi-enzymatic assay for in vivo transaminase high-throughput screening
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Creation of a lipase highly selective for trans fatty acids by protein engineering
Angewandte Chemie - International Edition
51,
412-4,
2012
, DOI
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High-throughput characterization and comparison of microbial communitiesComputational Medicine37-57
, Link
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Pseudomonas putida esterase contains a GGG(A)X-motif confering activity for the kinetic resolution of tertiary alcohols
Applied Microbiology and Biotechnology
93,
1119-26,
2012
, DOI
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Synthesis of Fluorinated Neurotransmitter AnaloguesFluorine in Pharmaceutical and Medicinal Chemistry : From Biophysical Aspects to Clinical Applications299-331
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Extracellular serine proteases from Stenotrophomonas maltophilia: screening, isolation and heterologous expression in E.coli.
Journal of Biotechnology
157,
140-147,
2012
, DOI
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C–X Bond Formation: Hydroxynitrile lyases: From Nature to ApplicationComprehensive Chirality350-371
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A New Esterase from Thermobifida halotolerans Hydrolyses Polyethylene Terephthalate (PET) and Polylactic Acid (PLA)
e-Polymers
4,
617-629,
2012
, DOI
, Link
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Recombinant expression and characterization of a zinc-dependent alcohol dehydrogenase from Yarrowia lipolytica
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Steroid biotransformations in biphasic systems with Yarrowia lipolytica expressing human liver cytochrome P450 genes
Microbial Cell Factories
11,
106,
2012
, DOI
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Expression of recombinant human flavin monooxygenase and moclobemide-N-oxide synthesis on multi-mg scale
Chemical Communications
48,
6001-6003,
2012
, DOI
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Saccharomyces cerevisiae as whole-cell biocatalyst for terpenoid production
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NITRILE REDUCTASE FROM GEOBACILLUS KAUSTOPHILUS: A POTENTIAL CATALYST FOR A NEW NITRILE BIOTRANSFORMATION REACTION
Advanced Synthesis & Catalysis
354,
2191-2198,
2012
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Identification and isolation of GPI anchored proteins from Pichia pastoris and their potential for surface display of recombinant proteins
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Expression of Recombinant Human Flavin Monooxygenases and application for N-oxidation of Moclobemide
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Recombinant expression and characterization of a zinc-dependent alcohol dehydrogenase from Yarrowia lipolytica.
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Crystallisation of the novel S-adenosyl-L-methionine dependent C-methyltransferase CouO from Streptomyces rishiriensis and preliminary diffraction data analysis. Acta Crystallogr., Sect. F: Struct. Biol. Cryst. Commun.
Acta Crystallographica / F
F68,
698-700,
2012
, DOI
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Pichia pastoris as whole-cell biocatalyst for (+)-nootkatone productionPichia 201248-48
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A NOVEL MULTI-ENZYMATIC ASSAY FOR TRANSAMINASE ACTIVITY: HIGH THROUGHPUT SCREENING APPLICATIONS IN PICHIA PASTORIS
Tetrahedron
68,
7586-7590,
2012
Show publication in PURE
Synthesis of 7-deazaguanine analogues including a novel biotransformation step
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Production of human cytochrome P450 2D6 drug metabolites with recombinant microbes--a comparative study
Biotechnology Journal
7,
1346-1358,
2012
, DOI
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Recombinant Human Flavin Monooxygenases: Expression and Moclobemide N-oxide Synthesis on Semi-Preparative ScaleNew BiotechnologyS236-S237
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Random mutagenesis in Pichia pastoris by resistance cassette transformation
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The role of surficial aminoacids on polyester hydrolysis by cutinases
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Identification, cloning, expression and characterization of a novel multifunctional sialyltransferase from Pasteurella dagmatis
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Crystallization of a novel metal-containing cupin from Acidobacterium sp. and preliminary diffraction data analysis
Acta Crystallographica / F
68,
451-454,
2012
, DOI
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Enzymatic Nitrile Reduction
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Recombinant Human Flavin Monooxygenases: Expression and Moclobemide N-oxide Synthesis on Semi-Preparative Scale
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Enzymatic functionalization of synthetic polymers via two-step enzymatic functionalisation
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Simple and efficient expression of Agaricus meleagris pyranose dehydrogenase in Pichia pastoris
Applied Microbiology and Biotechnology
94,
695-704,
2012
, DOI
, Link
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Phl p 4, an exciting allergen
Show publication in PURE
2011
Identification of the alpha mating factor from the improved draft genome sequence of Pichia pastoris CBS7435 and investigating its ability for secretory heterologous protein expression
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PLE - reintroducing a valuable biocatalyst into industrial processes
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Catalophore: Mining of structural databases using 3D-templates
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Hydrolysis of polyethyleneterephthalate by para-nitrobenzylesterase from Bacillus subtilis
Biotechnology Progress
27,
951-960,
2011
, DOI
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Methyltransferase NovO - a Versatile Catalyst for Enzymatic Friedel-Crafts Alkylation
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Nitrile Reduction using Nitrile Reductase
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High-quality genome sequence of Pichia pastoris CBS7435
Journal of Biotechnology
154,
312-320,
2011
, DOI
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Enzymatic Nitrile Reduction
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HIGH LEVEL EXPRESSION OF RHODOTORULA GRACILIS D-AMINO ACID OXIDASE IN PICHIA PASTORIS
Biotechnology Letters
33,
557-563,
2011
, DOI
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One-step enzyme extraction and immobilization for biocatalysis applications.
Molecular Biotechnology
6,
463-469,
2011
, DOI
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Comparative analysis of tertiary alcohol esterase activity in bacterial strains isolated from enrichment cultures and from screening strain libraries.
Applied Microbiology and Biotechnology
90,
929-939,
2011
, DOI
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Biocatalytic synthesis of optically active tertiary alcohols
Applied Microbiology and Biotechnology
91,
505-17,
2011
, DOI
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Biocatalytic strategies for the asymmetric synthesis of profens – recent trends and developments
Green Chemistry
,
2607-2618,
2011
, DOI
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Enzymatic Nitrile Reduction using wild type and mutant Nitrile Reductase QueF
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Protein engineering of arylmalonate decarboxylase G74C, an artificial racemase
Biotechnology International
23,
6-9,
2011
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Dramatically improved catalytic activity of an artificial (S)-selective arylmalonate decarboxylase by structure-guided directed evolution.
Chemical Communications
47,
7503-7505,
2011
, DOI
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Identification of novel esterases for the synthesis of sterically demanding chiral alcohols by sequence-structure guided genome mining
Journal of Molecular Catalysis B
70,
88-94,
2011
, DOI
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Enzymatic Surface Hydrolysis of PET. Effect of Structural Diversity on Kinetic Properties of Cutinases from Thermobifida
Macromolecules
44,
4632-4640,
2011
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The cadherin switch in melanoma instigated by HGF is mediated through epithelial-mesenchymal transition regulators.
Pigment cell & melanoma research
24,
382-385,
2011
, DOI
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A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistance
Metabolic Engineering
13,
555-569,
2011
, DOI
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Creation of a generally applicable NAD(P)+ regeneration system from a NADH specific NADH oxidase
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Characterization and engineering of cupin dioxygenases
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Production of a hypothetical sialyltransferase from P. dagmatis: Cloning, expression, purification and setup of a screening assay
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Old Yellow Enzyme catalyzed dehydrogenation of saturated ketones
Advanced Synthesis & Catalysis
252,
268-274,
2011
, DOI
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PREPARATION OF AN ENANTIOENRICHED TAXOL SIDECHAIN PRECURSOR BY NITRILASE AND NITRILE HYDRATASE
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Hydroxylation of polypropylene using the monooxygenase mutant 139-3 from Bacillus megaterium BM3
Biocatalysis and Biotransformation
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1-6,
2011
, DOI
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Identification of two enone-reductases by database mining using 3D active site templates
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Characterisation of bacterial hydroxynitrile lyases with high homology to cupin superfamily proteins
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Pichia pastoris as Whole-Cell Biocatalyst for (+)-Nootkatone Production
, Link
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Heterologous Expression of CYP71D55 in S. cerevisiae for (+)-Nootkatone Production
, Link
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Biocatalytic Friedel-Crafts Alkylation
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Development of a Bioinformatic Analytical Approach to Identify Novel Cancer Testis Antigens Involved in Meiosis
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Cupins as scaffolds for novel activities
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Transcriptional Activation of ZEB1 by Slug Leads to Cooperative Regulation of the EMT like Phenotype in Melanoma
The Journal of Investigative Dermatology
131,
1877-1885,
2011
, DOI
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Expression of a branched chain aminotransferase (BCAT) in Pichia pastoris: high throughput screening and process development
Show publication in PURE
2010
Biocatalytic Friedel-Crafts Alkylation
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Development of a Bioinformatic Analytical Approach to Identify and Characterise Novel Cancer Testis Antigens.
Show publication in PURE
Converting enzyme function and enantioselectivity of enzymes
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Engineering the Pichia pastoris methanol oxidation pathway for improved NADH regeneration during whole-cell biotransformation
Metabolic Engineering
12,
8-17,
2010
, DOI
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Hydroxynitrile lyases: Converting enzyme function and enantioselectivity
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Insights into the Secretory System of the Yeast Pichia pastoris
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Enantioselective kinetic resolution of phenylalkyl carboxylic acids using metagenome-derived esterases.
Microbial Biotechnology
3,
59-64,
2010
, DOI
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Directed evolution of Alcaligenes faecalis nitrilase
Enzyme and Microbial Technology
47,
140-146,
2010
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Engineering of choline oxidase from Arthrobacter nicotianae for potential use as biological bleach in detergents.
Applied Microbiology and Biotechnology
87,
1743-1752,
2010
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The role of the GGGX motif in determining the activity and enantioselectivity of pig liver esterase towards tertiary alcohols
Biocatalysis and Biotransformation
28,
201-208,
2010
, DOI
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Real time PCR based determination of gene copy numbers in Pichia pastoris
Biotechnology Journal
5,
10-10,
2010
, DOI
Show publication in PURE
Protein engineering and discovery of lipases
European Journal of Lipid Science and Technology
112,
64-74,
2010
, DOI
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The alpha/beta-hydrolase fold 3DM database (ABHDB) as a tool for protein engineering
ChemBioChem
11,
1635-1643,
2010
, DOI
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An Enzymatic Toolbox for the Kinetic Resolution of 2-(Pyridin- x -yl)but-3-yn-2-ols and Tertiary Cyanohydrins
European Journal of Organic Chemistry
,
2753-2758,
2010
, DOI
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Formation of chiral tertiary homoallylic alcohols via Evans aldol reaction or enzymatic resolution and their influence on the Sharpless asymmetric dihydroxylation
Tetrahedron
66,
3814-3823,
2010
, DOI
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Characterization of two Methyltransferases for Novel Biocatalytic C-C Bond Formation
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Changing the cofactor specificity of an NADH oxidase for efficient NADP+ recycling
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Identification of horseradish peroxidase isoenzymes and their heterologous expression in Pichia pastoris
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Characterization of two Methyltransferases for Novel Biocatalytic C-C Bond Formation
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Stepwise engineering of a Pichia pastoris D-amino acid whole cell catalyst
Microbial Cell Factories
9,
24-24,
2010
, DOI
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PRODUCTION, CHARACTERIZATION AND ENGINEERING OF HORSERADISH PEROXIDASE ISOENZYMES
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HGF-promoted motility in primary human melanocytes depends on CD44v6 regulated via NF-kappa B, Egr-1, and C/EBP-beta
The Journal of Investigative Dermatology
,
1893-1903,
2010
, DOI
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Development of a tailored D-Amino Acid Oxidase Expressing Whole Cell Biocatalyst
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IMPROVED FITNESS OF ARABIDOPSIS THALIANA NITRILASE 2
ChemCatChem
2,
263-267,
2010
, DOI
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C-terminal truncation of a metagenome-derived detergent protease for effective expression in E. coli.
Journal of Biotechnology
150,
408-416,
2010
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Perspectives on synthetic promoters for biocatalysis and biotransformation
ChemBioChem
11,
761-765,
2010
, DOI
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Characterisation of two bacterial hydroxynitrile lyases with high homology to cupin superfamily proteins
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Microbial PHA Production from Waste Raw MaterialsPlastics from Bacteria: Natural Functions and Applications85-119
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Engineered Alcaligenes faecalis nitrilases
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Monooxygenases as biocatalysts: classification, mechanistic aspects and biotechnological applications
Journal of Biotechnology
146,
9-24,
2010
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Expression and Characterization of Cytochrome P450 2D6 Variants in Pichia pastoris
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Hydroxynitrile lyases: Converting enzyme function and enantioselectivity
Show publication in PURE
Biocatalytic Friedel-Crafts Alkylation
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Optimisation of internal cofactor regeneration by host and expression engineering for the whole-cell bioreduction of carbonyl substrates
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Pig Liver Esterase - Re-introducing a Valuable Biocatalyst into Industrial Processes
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Biotransformation of Purine and Pyrimidine Carbonitriles
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