ORGC/News und Veranstaltungen/GÖCH Vorträge

Iminosugar-Based Galactoside Mimics as Pharmacological Chaperones for Lysosomal b-Galactosidases

Prof. Estelle Galienne,  Institut de Chimie Organique et Analytique (ICOA), Université d’Orléans

Date: 26.04.2017
Time: 17:00
Place: HS H "Ulrich Santner", NTEG230E, Technische Universität Graz, Kopernikusgasse 24, 8010 Graz, Erdgeschoß

As part of our research program dedicated to the design of new iminosugars as therapeutic agents for lysosomal storage disorders, we synthesized a diversity of iminosugar-based galactoside mimics and investigated them as pharmacological chaperones for mutant forms of lysosomal b-galactosidases, responsible for such devastating diseases as GM1-gangliosidosis, Morquio B and Krabbe diseases. The synthesis and biological evaluation of C-alkylated iminosugars in the l-arabino, d-galacto and l-ribo series will be presented, as well as recent results concerning the synthesis and the remarkable chaperone activity of C-alkylated derivatives of 4-epi-isofagomine.

Green nanotechnology- implications in nanomedicine for the creation of holistic integrative medicine (him)

Prof. Kattesh V Katti

Date: 28.04.2017
Time: 10:15
Place: HS 10.01, Heinrichstraße 28, Karl Franzens Universität Graz

Electro-organic Synthesis - Disruptive, Sustainable and Scalable

Prof. Siegfried Waldvogel, Universität Mainz

Datum: 21.06.2017
Uhrzeit: 17:15 Uhr
Ort: HS H "Ulrich Santner", NTEG230E, Technische Universität Graz, Kopernikusgasse 24, Erdgeschoß, 8010 Graz