2019
Arnold Stütz, Tanja Wrodnigg, Michael Schalli, Patrick Weber and Andreas Wolfsgruber Synthesis of modified 1,5‑imino‑d‑xylitols as ligands for lysosomal β‑glucocerebrosidase Monatshefte für Chemie = Chemical monthly 2019, 831-842, 2019
2018
Arnold Stütz, Tanja Wrodnigg and Patrick Weber Potent GH20 N-Acetyl-β-d-hexosaminidase Inhibitors: N-Substituted 3-acetamido-4-amino-5-hydroxymethyl-cyclopentanediols Molecules 2018, 2018
2017
Arnold Stütz, Michael Schalli, Martin Simon Thonhofer and Andreas Wolfsgruber C-5a-substituted validamine type glycosidase inhibitors. Carbohydrate research 2017, 1-9, 2017
Arnold Stütz, Michael Schalli and Martin Simon Thonhofer N-Substituted 5-amino-1-hydroxymethyl-cyclopentanetriols: A new family of activity promotors for a GM1-gangliosidosis related human lysosomal β-galactosidase mutant. Carbohydrate research 2017, 15-22, 2017
Arnold Stütz, Michael Schalli, Martin Simon Thonhofer and Patrick Weber A Morita-Baylis-Hillman based route to C-5a-chain-extended 4-epi-isofagomine type glycosidase inhibitors. Carbohydrate research 2017, 31-40, 2017
Arnold Stütz, Michael Schalli, Martin Simon Thonhofer and Patrick Weber A new type of pharmacological chaperone for GM1-gangliosidosis related human lysosomal β-galactosidase: N-Substituted 5-amino-1-hydroxymethyl-cyclopentanetriols. Bioorganic & Medicinal Chemistry Letters 2017, 3431-3435, 2017
2016
Arnold Stütz, Michael Schalli, Martin Simon Thonhofer and Patrick Weber Synthesis of C-5a-chain extended derivatives of 4-epi-isofagomine: Powerful beta-galactosidase inhibitors and low concentartion activators of GM1-gangliosidosis related human lysosomal beta-galactosidase Bioorganic & Medicinal Chemistry Letters 2016, 1438-1442, 2016
Arnold Stütz, Michael Schalli, Martin Simon Thonhofer and Patrick Weber Synthesis of C-5a-substituted derivatives of 4-epi-isofagomine: notable β-galactosidase inhibitors and activity promotors of GM1-gangliosidosis related human lysosomal β-galactosidase mutant R201C. Carbohydrate research 2016, 71-80, 2016
Arnold Stütz, Michael Schalli, Martin Simon Thonhofer and Patrick Weber Synthesis of C-5a-chain extended derivatives of 4-epi-isofagomine: Powerful β-galactosidase inhibitors and low concentration activators of GM1-gangliosidosis-related human lysosomal β-galactosidase. Bioorganic & Medicinal Chemistry Letters 2016, 1438-1442, 2016
Arnold Stütz and Tanja Wrodnigg Carbohydrate Processing Enzyme of the Lysosome: Diseases Caused by Missfolded Mutants and Sugar Mimetics as Correcting Pharmacological Chaperones Advances in Carbohydrate Chemistry and Biochemistry 2016, 225-302, 2016
Arnold Stütz, Michael Schalli and Martin Simon Thonhofer 5-Fluoro derivatives of 4-epi-isofagomine as D-galactosidase inhibitors and potential pharmacological chaperones for GM1-gangliosidosis as well as Fabry's disease Carbohydrate research 2016, 6-12, 2016
Arnold Stütz, Hansjörg Weber, Michael Schalli, Martin Simon Thonhofer and Andreas Wolfsgruber From secondary alcohols to tertiary fluoro substituents: A simple route to hydroxymethyl branched sugars with a fluorine substituent at the branching point Carbohydrate research 2016, 11-19, 2016
2013
Arnold Stütz and Tanja Wrodnigg Positive attitude, shape, flexibility, added-value accessories or "just being different": How to attract a glycosidasePositive attitude, shape, flexibility, added-value accessories or "just being different": How to attract a glycosidase120-149
2012
Tanja Wrodnigg and Arnold Stütz Fluorous Iminoalditols act as Effective Pharmacological Chaperones against Gene Products from GLB1 Alleles causing GM1-Gangliosidosis and Morquio B Disease Journal of inherited metabolic disease 2012, 495-503, 2012
Arnold Stütz and Tanja Wrodnigg Two Faces of Iminoalditols: Powerful Inhibitors Trigger Glycosidase Activation Current enzyme inhibition 2012, 47-99, 2012
Arnold Stütz and Tanja Wrodnigg Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase Proceedings of the National Academy of Sciences of the United States of America 2012, 781-786, 2012
Arnold Stütz and Tanja Wrodnigg The Amadori Rearrangement as Glycoconjugation Method: Synthesis of Non-natural C-Glycosyl Type Glycoconjugates Beilstein Journal of Organic Chemistry 2012, 1619-1629, 2012
Arnold Stütz and Tanja Wrodnigg The Two Faces of Iminoalditols: Powerful Inhibitors Trigger Glycosidase Activation Current enzyme inhibition 2012, 47-99, 2012
2011
Arnold Stütz and Tanja Wrodnigg Iminosugars and glycoside hydrolases: Historic context, current aspects, emerging trends Advances in Carbohydrate Chemistry and Biochemistry 2011, 187-298, 2011
Tanja Wrodnigg and Arnold Stütz A Fluorescent Probe for GM1 Gangliosidosis Related -Gal: N-(Dansylamino)hexylaminocarbonyl- pentyl-1,5-dideoxy-1,5-imino-D-galactitol Bioorganic & Medicinal Chemistry Letters 2011, 6872-6875, 2011
Tanja Wrodnigg and Arnold Stütz 1-Deoxy-D-galactonojirimycins with Dansyl Capped N-Substituents as -Galactosidase Inhibitors and Potential Probes for GM1 Gangliosidosis Affected Cell Lines Carbohydrate research 2011, 1592-1598, 2011
2010
Arnold Stütz, Tanja Wrodnigg and Martin Simon Thonhofer Synthesis of Lipophilic 1-Deoxygalactonojirimycin Derivatives as Galactosidase Inhibitors Beilstein Journal of Organic Chemistry 2010, 2010
Tanja Wrodnigg and Arnold Stütz DLHex-DGJ, a Novel Derivative of 1-Deoxygalactonojirimycin with Pharmalogical Chaperone Activity in Human GM1-Gangliosidosis Fibroplasts Molecular genetics and metabolism 2010, 262-268, 2010
Tanja Wrodnigg and Arnold Stütz Fluorescent-tagged sp2-iminosugars with potential b-glucosidase inhibitory activity Bioorganic & Medicinal Chemistry 2010, 7439-7445, 2010
Arnold Stütz and Tanja Wrodnigg 1-Deoxynojirimycins with Dansyl Capped N-Substituents as Probes for Morbus Gaucher Affected Cell Lines Carbohydrate research 2010, 1371-1376, 2010
Arnold Stütz, Tanja Wrodnigg, Martin Simon Thonhofer and Carina Illaszewicz-Trattner Fluorous Iminoalditols: A New Family of N-Modified Glycosidase Inhibitors ChemBioChem 2010, 2026-2033, 2010
Arnold Stütz and Tanja Wrodnigg Biotin-Iminoalditol Conjugates: Molecular Probes for Glycosylhydrolases Bioorganic & Medicinal Chemistry Letters 2010, 4077-4079, 2010
2009
Arnold Stütz Synthesis and biological evaluation of 1,5-dideoxy-1,5-iminoxylitol-amino acid hybrids as xylosidase inhibitors Australian Journal of Chemistry 2009, 553-557, 2009
Arnold Stütz and Tanja Wrodnigg 2-Acetamino-1,2-dideoxynojirimycin-lysine hybrids as hexosaminidase inhibitors Tetrahedron / Asymmetry 2009, 832-835, 2009
2008
Tanja Wrodnigg and Arnold Stütz Glycosidase Profiling with Immobilised Glycosidase Inhibiting Iminoalditols – A Proof-of-Concept Study Bioorganic & Medicinal Chemistry Letters 2008, 1922-1925, 2008
Arnold Stütz 1-Deoxygalactonojirimycin-lysine hybrids as potent beta-galactosidase inhibitors Bioorganic & Medicinal Chemistry 2008, 10216-10220, 2008
2007
Arnold Stütz and Tanja Wrodnigg Iminoalditol-amino acid hybrids: synthesis and evaluation as glycosidase inhibitors Carbohydrate research 2007, 1850-1858, 2007
Arnold Stütz 1,5-Anhydro-D-fructose from D-fructose Carbohydrate research 2007, 1249-1253, 2007
2006
Arnold Stütz Synthesis of 1,4-anhydro-D-fructose and 1,4-anhydro-D-tagatose Carbohydrate research 2006, 1737-1742, 2006
Tanja Wrodnigg and Arnold Stütz Fluorescent glycosidase inhibiting 1,5-dideoxy-1,5-iminoalditols Bioorganic & Medicinal Chemistry Letters 2006, 2067-2070, 2006
Arnold Stütz and Tanja Wrodnigg L-Idoseptanosides: substrates of D-glucosidases Tetrahedron / Asymmetry 2006, 234-239, 2006
Arnold Stütz and Tanja Wrodnigg Sugars with Endocyclic Heteroatoms Other than OxygenSugars with Endocyclic Heteroatoms Other than Oxygen
Arnold Stütz and Tanja Wrodnigg Fine Tuning of b-Glucosidase Inhibitory Activity in the 2,5-Dideoxy-2,5-imino-D-mannitol (DMDP) System Carbohydrate research 2006, 1717-1722, 2006
Arnold Stütz and Tanja Wrodnigg Fluorescent glycosidase inhibiting 1,5-iminoalditols Bioorganic & Medicinal Chemistry Letters 2006, 2067-2070, 2006
Arnold Stütz and Tanja Wrodnigg Synthesis of N-Protected Galactosamine Building Blocks from D-Tagatose via the Heyns Rearrangement Journal of carbohydrate chemistry 2006, 33-41, 2006
Tanja Wrodnigg and Arnold Stütz Fluorescently tagged iminoalditol glycosidase inhibitors as novel biological probes and diagnostics Bioorganic & Medicinal Chemistry 2006, 1737-1742, 2006
2005
Tanja Wrodnigg and Arnold Stütz Non-natural aldofuranosides as substrates of a beta-glucosidase Tetrahedron / Asymmetry 2005, 159-165, 2005
Arnold Stütz and Tanja Wrodnigg Sugar with endocyclic heteroatoms other than oxygenSugar with endocyclic heteroatoms other than oxygen383-424
2004
Arnold Stütz Simple syntheses of 4-O-glucosylated 1-deoxynojirimycins from maltose and cellobiose Carbohydrate research 2004, 2615-2619, 2004
Arnold Stütz and Tanja Wrodnigg Probing the aglycon binding site of β–glucosidase: a collection of C-1-modified 2,5-dideoxy-2,5-imino-D-mannitol derivatives and their structure-activity relationships as competitive inhibitors Bioorganic & Medicinal Chemistry 2004, 3485-3495, 2004
Arnold Stütz Golgi endomannosidase inhibitor, alpha-D-glucopyranosyl-(1-3)-1-deoxynojirimycin: A five step synthesis from maltulose and examples of N-modified derivatives Carbohydrate research 2004, 1823-1827, 2004
2003
Arnold Stütz and Tanja Wrodnigg Iminosugars and relatives as antiviral and potential antiinfective agents Current topics in medicinal chemistry 2003, 513-523, 2003
Arnold Stütz, Tanja Wrodnigg and Carina Illaszewicz-Trattner An exceptionally simple chemical synthesis of O-glycosylated D-glucosamine derivatives by Heyns rearrangement of the corresponding O-glycosyl fructoses Journal of carbohydrate chemistry 2003, 253-265, 2003
2002
Arnold Stütz Timely research perspectives in carbohydrate chemistry
Arnold Stütz A simple method for the preparation of 1-deoxynojirimycin from D-fructose Carbohydrate research 2002, 183-186, 2002
Tanja Wrodnigg and Arnold Stütz A Simple Access to the D-Mannosidase Inhibitor 1-Deoxynojirimycin Carbohydrate research 2002, 183-186, 2002
Arnold Stütz N-Alkylated Derivatives of 1,5-Dideoxy-1,5-iminoxylitol as beta-Xylosidase and beta-Glucosidase Inhibitors Monatshefte für Chemie = Chemical monthly 2002, 555-560, 2002
2001
Tanja Wrodnigg and Arnold Stütz Novel lipophilic derivatives of 2,5-dideoxy-2,5-imino-D-mannitol (DMDP) are powerful beta-glucosidase inhibitors Bioorganic & Medicinal Chemistry Letters 2001, 1063-1064, 2001
Arnold Stütz and Hansjörg Weber D-Xylose (D-glucose) isomerase: Some observations and comments concerning structural requirements of substrates as well as mechanistic features Journal of carbohydrate chemistry 2001, 239-256, 2001
Arnold Stütz Epimerisation, isomerisation and rearrangement reactions of carbohydrates
Arnold Stütz and Tanja Wrodnigg Thia and other changes in the ring (glycomimetics)Thia and other changes in the ring (glycomimetics)2663-2678
Arnold Stütz and Tanja Wrodnigg Sulfur Containing GlycomimeticsSulfur Containing Glycomimetics2663-2678
Arnold Stütz and Tanja Wrodnigg Powerful probes for glycosidases: Novel fluorescently tagged glycosidase inhibitors Bioorganic & Medicinal Chemistry Letters 2001, 1339-1342, 2001
Arnold Stütz D-Xylose (D-glucose) isomerase and related enzymes in carbohydrate synthesis Topics in current chemistry 2001, 77-114, 2001
Arnold Stütz Ethambutol analogues as potential antimycobacterial agents Bioorganic & Medicinal Chemistry Letters 2001, 1679-1681, 2001
Arnold Stütz and Tanja Wrodnigg Enzymatic O-galactosylation of selected free and partially protected ketohexoses Journal of carbohydrate chemistry 2001, 647-657, 2001
2000
Arnold Stütz and Tanja Wrodnigg Sugar analogues with basic nitrogen in the ring as anti-infectives Journal of carbohydrate chemistry 2000, 435-449, 2000
Arnold Stütz and Tanja Wrodnigg Olefin metathesis in carbohydrate synthesis Current organic chemistry 2000, 565-588, 2000
Tanja Wrodnigg and Arnold Stütz Biologically active 1-aminodeoxy derivatives of the powerful glucosidase inhibitor 2,5-dideoxy-2,5-imino-D-mannitol Journal of carbohydrate chemistry 2000, 975-990, 2000
Arnold Stütz Synthesis of 5,6-dimodified open-chain D-fructose derivatives and their properties as substrates of bacterial polyol dehydrogenase Tetrahedron / Asymmetry 2000, 607-620, 2000
Arnold Stütz Syntheses of sugar related trihydroxyazepanes from simple carbohydrates and their activities as reversible glycosidase inhibitors Carbohydrate research 2000, 22-33, 2000
1999
Arnold Stütz Synthetic application of glucose isomerase: Isomerisation of C-5 modified (2R,3R,4R)-configured hexoses into the corresponding 2-ketoses Carbohydrate research 1999, 55-62, 1999
Arnold Stütz Steroselective olefin metathesis of omega-enosugars Synlett 1999, 1787-1789, 1999
Arnold Stütz Iminosugars as glycosidase inhibitors3-527-29544-5
Arnold Stütz and Tanja Wrodnigg Sophisticated products from cheap renewable sources: glucuronic acid, sucrose, and D-mannitol in natural products synthesis Recent research developments in organic chemistry 1999, 319-342, 1999
Arnold Stütz Chemical and chemo-enzymatic approaches to unnatural ketoses and glycosidase inhibitors with basic nitrogen in the sugar ring Current organic chemistry 1999, 235-251, 1999
Arnold Stütz Some reflections on structure-activity relationships in glycosidase inhibiting iminoalditols and iminosugarsSome reflections on structure-activity relationships in glycosidase inhibiting iminoalditols and iminosugars157-187
Arnold Stütz Binding energy and specificity in the catalytic mechanism of yeast aldose reductases Biochemical Journal 1999, 101-108, 1999
Arnold Stütz and Tanja Wrodnigg Tables of glycosidase inhibitors with basic nitrogen in the sugar ring and their inhibitory activitiesTables of glycosidase inhibitors with basic nitrogen in the sugar ring and their inhibitory activities254-390
Arnold Stütz and Tanja Wrodnigg The Heyns Rearrangement Revisited: An Exceptionally Simple Two-Step Chemical Synthesis of N-Acetyl-D-lactosamine from Lactulose Angewandte Chemie / International Edition 1999, 827-828, 1999
Arnold Stütz Unnatural 5,6-dimodified D-glucose derivatives are superior substrates of microbial aldose reductases Bioorganic & Medicinal Chemistry Letters 1999, 1683-1686, 1999
Anna De Raadt and Arnold Stütz Iminoalditols as affinity ligands for the isolation of glycosidasesIminoalditols as affinity ligands for the isolation of glycosidases207-215
Arnold Stütz and Tanja Wrodnigg Sophisticated Products from Cheap Renewable Sources: Glucuronic Acid, Sucrose, and D-Mannitol in Natural Product Synthesis Recent research developments in organic chemistry 1999, 319-342, 1999
1998
Arnold Stütz Nickel(II) catalysed reactions of free D-fructose derivatives modified at positions five and/or six Journal of carbohydrate chemistry 1998, 1259-1267, 1998
Arnold Stütz Synthesis of regio- and stereospecifically C-deuterated derivatives of glycosidase inhibitors 1-deoxymannojirimycin and 2,5-dideoxy-2,5-imino-D-mannitol by intramolecular reductive amination employing deuterium gas Carbohydrate research 1998, 367-374, 1998
Arnold Stütz Glucose isomerase catalysed isomerisation reactions of (2R,3R)-configured aldoses to the corresponding ketoses Carbohydrate research 1998, 331-336, 1998
Arnold Stütz Nickel(II) catalysed transformations of 5-azido-5-deoxy-D-glucofuranose and of 5-azido-5-deoxy-L-idofuranose Journal of carbohydrate chemistry 1998, 241-247, 1998
1997
Arnold Stütz and Karl Dax Synthesis of a novel alpha-glucoside of the powerful glucosidase inhibitor 2,5-dideoxy-2,5-imino-D-mannitol via enzymatic glucosylation of 5-azido-5-deoxy-D-glucofuranose Tetrahedron letters 1997, 225-226, 1997
Arnold Stütz and Tanja Wrodnigg Synthesis of 1-amino-1,2,5-trideoxy-2,5-imino-D-mannitol, a novel analogue of the powerful glucosidase inhibitor 2,5-dideoxy-2,5-imino-D-mannitol, via an Amadori rearrangement of 5-azido-5-deoxy-D-glucofuranose Tetrahedron letters 1997, 5463-5466, 1997
Arnold Stütz A sucrose based approach to enantiomerically pure glycerol derivatives Journal of carbohydrate chemistry 1997, 1293-1303, 1997
Arnold Stütz and Tanja Wrodnigg Two isosteric fluorinated derivatives of the powerful glucosidase inhibitors 1-deoxynojirimycin and 2,5-dideoxy-2,5-imino-D-mannitol: Syntheses and glucosidase inhibitory activities of 1,2,5-trideoxy-2-fluoro-1,5-imino-D-glucitol and of.... Carbohydrate research 1997, 155-166, 1997
Arnold Stütz and Anna De Raadt Chemical and chemo-enzymatc approaches to glycosidase inhibitors with basic nitrogen in the sugar ring Topics in current chemistry 1997, 157-186, 1997
1996
Arnold Stütz A novel approach to the 1-deoxynojirimycin system: Synthesis, from sucrose, of 2-acetamido-1,2-dideoxynojirimycin as well as some 2-N-modified derivatives Carbohydrate research 1996, 49-57, 1996
Arnold Stütz A novel innovative approach aims to clarify the reaction mechanism of retaining glycoside hydrolases Angewandte Chemie / International Edition 1996, 1926-1928, 1996
1995
Arnold Stütz and Anna De Raadt A mechanistic look at some methods of metal ion catalysed chemical and enzymatic isomerisation of free sugars Advances in Detailed Reaction Mechanisms 1995, 175-211, 1995
Arnold Stütz Synthesis of 1,5-dideoxy-1,5-imino-D-arabinitol (5-nor-L-fuco-1-deoxynojirimycin) and its application for the affinity purification and characterisation of alpha-L-fucosidase Carbohydrate research 1995, 17-30, 1995
Arnold Stütz Synthesis of (1-13C)-1-deoxynojirimycin Tetrahedron letters 1995, 4989-4990, 1995
1994
Arnold Stütz and Anna De Raadt Glucose isomerase (EC 5.3.1.5) as a reagent in carbohydrate synthesis: Success and failures with the isomerisation of non-natural derivatives of D-glucose into the corresponding 2-ketoses Catalysis today 1994, 549-561, 1994
1993
Arnold Stütz 2,5-dideoxy-2,5-imino-D-mannitol and -D-glucitol. Two step bio-organic syntheses from 5-azido-5-deoxy-D-glucofuranose and -L-idofuranose, respectively, evaluation as glucosidase inhibitors and an application in affinity purification and.... Carbohydrate research 1993, 67-77, 1993
Arnold Stütz and Karl Dax The crystal and molecular structures of 1,2,3,4,5,6,7,8-octa-O-acetyl-L-threo-L-altro- and -L-threo-L-galacto-octitol Carbohydrate research 1993, 21-28, 1993
Arnold Stütz and Karl Dax Synthese von (+)-Castanospermin und 1-epi-Castanospermin aus D-Glucofuranurono-6,3-lacton durch Reformatsky-Reaktion Liebigs Annalen der Chemie (1979 - 1994) 1993, 379-390, 1993
Herfried Griengl, Anna De Raadt, Arnold Stütz and Norbert Klempier A mild and simple enzymatic conversion of aldono and aldurononitriles into the corresponding amides and/or carboxylic acids The journal of organic chemistry 1993, 3179-3184, 1993

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