Atglistatin can reduce the fatty acid level in the blood, which is causal for type II diabetes, non-alcoholic fatty liver or cardiac insufficiency. Researchers from the University of Graz and TU Graz are going one step further and make the active substance fit for use in the human organism.
An international research team has successfully developed and tested a concept in which nerves are stimulated with light pulses. The method provides considerable advantages for medicine and opens up a wide range of possible applications.
Study led by TU Graz shows that apple trees inherit their microbiome to the same extent as their genes. The results lay the foundation for new breeding strategies for healthy and climate-robust fruit and vegetables.
For the first time ever, the intention of a continuous movement was able to be read out from non-invasive brain signals at TU Graz. This success enables more natural and non-invasive control of neuroprostheses to be carried out in real time.
Graz was instrumental in the birth of biomedical engineering in Austria 50 years ago – a step that laid the foundations for a long record of research successes. Today, numerous institutes work at the intersection between medicine and technology.
The computer model, developed under the lead management of researchers at TU Graz, simulates the cyclical changes in the membrane potential of a cancer cell using the example of human lung adenocarcinoma and opens up completely new avenues in cancer research.
The extent to which the composition of the microbiome of apples and oil pumpkins depends on the geographical location and what insights can be derived from this for breeding, health and shelf life of the fruits is shown in two recent publications by researchers at TU Graz.
With their expertise in microbiome research, the researchers at the Institute of Environmental Biotechnology were able to demonstrate how a specific bacterium inside the seeds of rice plants effectively and in an eco-friendly way inhibits destructive plant pathogens.
A multi-channel recording device developed at TU Graz for pathological lung sounds and associated automatic lung sound analysis could support existing screening methods for early detection of, for example, Covid-19 infections. This now requires clinical data and interdisciplinary collaboration.
The role of the enzyme dipeptidyl peptidase 3 in the blood pressure-regulating renin-angiotensin system was investigated in the inter-university cooperation project BioTechMed-Graz. The results could pave the way for new therapies for cardio-renal diseases.
Researchers from TU Graz and Ruhr University Bochum show in the journal ACS Catalysis how the catalytic activity of cyanobacteria, also known as blue-green algae, can be significantly increased. This brings biotechnological and thus eco-friendly application a big step closer.
Researchers from Graz, Austria, are developing a ground-breaking method that uses biomarkers to detect sepsis 2 to 3 days before the first clinical symptoms appear. This can significantly increase the chances of survival in cases of blood poisoning by bacteria or fungi.
Over the last two decades researchers have been working on a contrast-agent free magnetic resonance imaging (MRI) method called Arterial Spin Labeling (ASL) for detecting blood flow changes within the brain and other organs. Recent improvements in imaging hardware, new strategies for efficient data...
Spectators will experience the fascinating power of thought-controlled systems on 17 September, as teams from all over the world go head to head in the CYBATHLON BCI Series 2019 at TU Graz. ‘Pilots’ who are paralysed from the neck down control avatars using brain-computer interfaces in a specially...
TU Graz researchers managed for the first time ever to ‘retrain’ an enzyme to build ring-shaped molecular structures instead of performing its natural task of reducing double bonds. The work was published in Angewandte Chemie, and is relevant for the production of pharmaceuticals and plant...
Illnesses such as cancer and multiple sclerosis may also be associated with lipids. Disorders are difficult to assess due to the diversity of lipids. Graz scientists present a new tool for the analysis of lipids in Nature Methods.
The agent Atglistatin can reduce the level of fatty acid in the blood. Funded by the Austrian Research Promotion Agency, researchers at the University of Graz and TU Graz want to further develop the agent into a medicine to treat metabolic disorders.
For the first time ever, researchers at TU Graz and the Medical University of Graz have managed to functionally characterise the three-dimensional interaction between red-light receptors and enzymatic effectors. The results, with implications for optogenetics, have been published in Science...
Researchers with ERC Grants within the Field of Expertise:
CD lab within the Field of Expertise:
The Field of Expertise is involved in the following lead projects at TU Graz:
from left to right:
Univ.-Prof. Dipl.-Ing. Dr.techn.
Institute of Neural Engineering
Univ.-Prof. Dipl.-Biol. Dr.rer.nat.
Institute of Environmental Biotechnology
Univ.-Prof. Dipl.-Ing. Dr.techn.
Institute of Biotechnology and Biochemical Engineering