2016
Arnold Stütz, Michael Schalli, Martin Simon Thonhofer and Patrick Weber Synthesis of C-5a-chain extended derivatives of 4-epi-isofagomine: Powerful beta-galactosidase inhibitors and low concentartion activators of GM1-gangliosidosis related human lysosomal beta-galactosidase Bioorganic & Medicinal Chemistry Letters 2016, 1438-1442, 2016
Arnold Stütz, Michael Schalli, Martin Simon Thonhofer and Patrick Weber Synthesis of C-5a-substituted derivatives of 4-epi-isofagomine: notable β-galactosidase inhibitors and activity promotors of GM1-gangliosidosis related human lysosomal β-galactosidase mutant R201C. Carbohydrate research 2016, 71-80, 2016
Arnold Stütz, Michael Schalli, Martin Simon Thonhofer and Patrick Weber Synthesis of C-5a-chain extended derivatives of 4-epi-isofagomine: Powerful β-galactosidase inhibitors and low concentration activators of GM1-gangliosidosis-related human lysosomal β-galactosidase. Bioorganic & Medicinal Chemistry Letters 2016, 1438-1442, 2016
2013
Rolf Breinbauer and Mario Leypold Racemization-Free Chemoenzymatic Peptide Synthesis Enabled by the Ruthenium-Catalyzed Synthesis of Peptide Enol Esters via Alkyne-Addition and Subsequent Conversion Using Alcalase-Cross-Linked Enzyme Aggregates Advanced Synthesis & Catalysis 2013, 1799-1807, 2013
Rolf Breinbauer Investigation of the origin and synthetic application of the pseudodilution effect for Pd-catalyzed macrocyclisations in concentrated solutions with immobilized catalysts Organic & biomolecular chemistry 2013, 4750-4756, 2013
2012
Mario Leypold Racemization-Free Chemoenzymatic Peptide Synthesis Enabled by the Ru-Catalyzed Synthesis of Peptide Enolesters via Alkyne-Addition and Subsequent Conversion Using Alcalase-CLEA
Crystallisation of the novel S-adenosyl-L-methionine dependent C-methyltransferase CouO from Streptomyces rishiriensis and preliminary diffraction data analysis. Acta Crystallogr., Sect. F: Struct. Biol. Cryst. Commun. Acta Crystallographica / F 2012, 698-700, 2012
2010
Rolf Breinbauer A simple synthesis of functionalized 3-methyl-1-pyridinyl-1H-imidazolium salts as bidentate N-heterocyclic-carbene precursors and their application in Ir-catalyzed arene borylation Tetrahedron letters 2010, 6622-6625, 2010
2008
Hansjörg Weber Characterization of recombinant Aspergillus fumigatus mannitol-1-phosphate 5-dehydrogenase and its application for the stereoselective synthesis of protio and deuterio forms of D-mannitol 1-phosphate Carbohydrate research 2008, 1414-1423, 2008
Tanja Wrodnigg Novel N-Modified Derivatives of 1-Deoxygalactonojirimycin are Powerful Inhibitors of Galactosidases and Restore Mutant Galactosidase Activity in a GM1-Gangliosidosis Cell Line
Tanja Wrodnigg Regioselective Intramolecular Ring Closure of 2-Amino-6-bromo-2,6-dideoxyhexono-1,4-lactones to 5- or 6-Membered Iminuronic Acid Analogues: Synthesis of 1-Deoxymannojirimycin and of 2,5-Dideoxy-2,5-imino-D-glucitol" Organic & biomolecular chemistry 2008, 1779-1786, 2008
Tanja Wrodnigg Helping Glycosidases with Glycosidase Inhibitors: Design and Evaluation of Inhibitors as Potential Chemical Chaperones Based on Active Site Structure Data of Lysosomal Glycosidases
2007
Herfried Griengl Überwindung der thermodynamischen und kinetischen Limitierungen Aldolase-katalysierter Reaktionen durch multienzymatische dynamische kinetische asymmetrische Umwandlungen Angewandte Chemie / International Edition 2007, 1648-1651, 2007
2005
Herfried Griengl and Anna De Raadt Chiral Auxiliaries as Docking/Protecting Groups in Biohydroxylation: (S)-Specific Hydroxylation of Enantiopure tert-Butyl-Substituted Spirooxazolidines Derived from Cyclopentanone European journal of organic chemistry 2005, 793-796, 2005
2004
Arnold Stütz and Tanja Wrodnigg Probing the aglycon binding site of β–glucosidase: a collection of C-1-modified 2,5-dideoxy-2,5-imino-D-mannitol derivatives and their structure-activity relationships as competitive inhibitors Bioorganic & Medicinal Chemistry 2004, 3485-3495, 2004
2003
Herfried Griengl Novel Acess to Chiral 1,1'-Disubstituted Ferrocene Derivatives via Doubled Stereoselecitive Cyanohydrin Synthesis Exploiting the Hydroxy Nitrile Lyase from Hevea brasiliensis Tetrahedron / Asymmetry 2003, 355-362, 2003
2002
Arnold Stütz and Tanja Wrodnigg A simple five step synthesis from maltulose of the endomannosidase inhibitor 3-O-(alpha-D-glucopyranosyl)-1-deoxynojirimycin allows convenient access to a range of applications
2000
Hansjörg Weber, Herfried Griengl, Anna De Raadt and Peter Plachota Chiral Auxiliaries as Docking/protecting groups in Biohydroxylation: The Hydroxylation of Enantiopure Spiroooxyzolidines Derived from Cyclopentanone Using Beauveria bassiana ATCC 7159, European journal of organic chemistry 2000, 3835-3847, 2000
1999
Herfried Griengl Induction and Functional Role of Cytochrome P450 in the Filamentous Fungi Mortierella alpina ATCC 8979 and Cunninghamella blakesleeana DSM 1906 During Hydroxylation of Cycloalkylbenzoxzoles Applied Microbiology and Biotechnology 1999, 516-522, 1999
1998
Arnold Stütz Synthesis of regio- and stereospecifically C-deuterated derivatives of glycosidase inhibitors 1-deoxymannojirimycin and 2,5-dideoxy-2,5-imino-D-mannitol by intramolecular reductive amination employing deuterium gas Carbohydrate research 1998, 367-374, 1998
1997
Tanja Wrodnigg Modellierung des Bindungsverhaltens von zuckerähnlichen Glycosidasenhemmern mit basischem Stickstoff statt Sauerstoff im Ring am Enzym Glucoamylase anhand von Strukturdaten
Arnold Stütz and Tanja Wrodnigg Synthesis of 1-amino-1,2,5-trideoxy-2,5-imino-D-mannitol, a novel analogue of the powerful glucosidase inhibitor 2,5-dideoxy-2,5-imino-D-mannitol, via an Amadori rearrangement of 5-azido-5-deoxy-D-glucofuranose Tetrahedron letters 1997, 5463-5466, 1997
Arnold Stütz and Tanja Wrodnigg Two isosteric fluorinated derivatives of the powerful glucosidase inhibitors 1-deoxynojirimycin and 2,5-dideoxy-2,5-imino-D-mannitol: Syntheses and glucosidase inhibitory activities of 1,2,5-trideoxy-2-fluoro-1,5-imino-D-glucitol and of.... Carbohydrate research 1997, 155-166, 1997
1996
Arnold Stütz and Tanja Wrodnigg New Results on the Substrate-Tolerance of Glucose-Isomerase (EC 5.3.1.5): Chemo-Enzymatic Preparation of Enantiomerically Pure Chiral Building Blocks and Intermediates in Natural Products Synthesis
1994
Arnold Stütz and Anna De Raadt Glucose isomerase (EC 5.3.1.5) as a reagent in carbohydrate synthesis: Success and failures with the isomerisation of non-natural derivatives of D-glucose into the corresponding 2-ketoses Catalysis today 1994, 549-561, 1994
1993
Arnold Stütz 2,5-dideoxy-2,5-imino-D-mannitol and -D-glucitol. Two step bio-organic syntheses from 5-azido-5-deoxy-D-glucofuranose and -L-idofuranose, respectively, evaluation as glucosidase inhibitors and an application in affinity purification and.... Carbohydrate research 1993, 67-77, 1993