HCE/Research & Working Groups/Research Groups/Research Groups
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Research group Computational and Experimental Physiology

The research group Computational and Experimental Physiology deals with the analysis, modeling and simulation in the fields of cardiovascular and neurophysiology, cellulr and systemic pathophysiology and the experimental electrophysiology and sensor technology as well as their clinical translation.

Members

David Benedict Baumgartner
Sonja Langthaler
Dipl.-Ing. BSc

Institute of Health Care Engineering with European Testing Center of Medical Devices
Stremayrgasse 16/II
8010 Graz

Phone
+43 (316) 873 - 7895
Fax
+43 (316) 873 - 107895
Theresa Margarethe Rienmüller
Ass.Prof. Dipl.-Ing. Dr.techn.

Institute of Health Care Engineering with European Testing Center of Medical Devices
Stremayrgasse 16/II
8010 Graz

Phone
+43 (316) 873 - 7396
Fax
+43 (316) 873 - 107396
Sara Stoppacher
Dipl.-Ing. BSc

Institute of Health Care Engineering with European Testing Center of Medical Devices
Stremayrgasse 16/II
8010 Graz

Phone
+43 (316) 873 - 7397
Fax
+43 (316) 873 - 107397
Daniel Ziesel
Dipl.-Ing. BSc

Institute of Health Care Engineering with European Testing Center of Medical Devices
Stremayrgasse 16/II
8010 Graz

Phone
+43 (316) 873 - 4464
Fax
+43 (316) 873 - 104464

Research Projects

FWF - LOGOS-TBI - Light-controlled organic semiconductor implants for regeneration after TBI
Background: Traumatic brain injury (TBI) is a leading cause of death and disability among young adults. The impairment of the often very young patients in daily life is a heavy burden for the affected person and leads to high healthcare costs. In recent years, electrostimulation of neurons has been suggested a promising approach to induce functional recovery of injured neuronal connections. However, standard electrode stimulation techniques require invasive methods and wiring of the patient. Purpose: We aim to combat TBI-induced disabilities by re-establishing neuronal connectivity. We will use light-sensitive semiconductors (photocaps) made from industrial colorants. They are easily available, stable, and non-toxic. Photocaps enable electrical stimulation of neurons with safe light intensities without the need for external wiring. Hypothesis: We suppose that the stimulation of neuronal cells via light-activated photocaps fosters functional recovery after TBI. Approach: In a multidisciplinary research approach we investigate the photocaps’ performance and effects on living systems. Cultured cells are an invaluable tool to develop optimal stimulation parameters before progressing to healthy and injured brain tissue. We will investigate the optimal time window after TBI in which stimulation yields the most extensive regenerative results. Our interdisciplinary research program brings together young independent researchers with backgrounds from neuroscience (Dr. Muammer Ücal), structural biology (Dr. Karin Kornmüller), electrophysiology (Dr. Susanne Scherübel) and electrical engineering (Dr. Theresa Rienmüller). Experiments will be conducted at the Medical University of Graz and Graz University of Technology.
Start: 30.04.2019
STEP - Conceptual design of a validation environment for the standardized examination of defibrillator pads
The aim of this project is to develop a test environment for defibrillation electrode pads which allows examining the electrodes in accordance with applicable standards and regulations regarding their function and safe usage.
Start: 28.02.2016
Cardiovascular Engineering
This interdisciplinary research project is concerned with the quantitative determination of myocardial perfusion based on dynamic CT-scans, particularly in terms of physiological determinants and patophysiological changes as well as after administration of drug therapy or cardiovascular surgery.
Start: 31.10.2015
Contact
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Institute of Health Care Engineering with European Testing Center of Medical Devices
Stremayrgasse 16/II
8010 Graz

Tel.: +43 (0) 316 / 873 - 7378
Fax: +43 (0) 316 / 873 - 107378
petra.schmiednoSpam@tugraz.at
hce.tugraz.at

Head
Univ.-Prof. Dr. Christian Baumgartner